1. A method for transmitting a pilot signal, comprising:
performing orthogonal frequency division multiplex modulation on the pilot signal; and
transmitting the modulated pilot signal in a first andor last orthogonal frequency division multiplex symbol of a sub-frame in which the pilot signal is transmitted.
2. The method according to claim 1, wherein performing orthogonal frequency division multiplex modulation on the pilot signal comprises:
mapping the pilot signal to a set of even sub-carriers of the first andor last orthogonal frequency division multiplex symbol to generate a frequency-domain pilot signal; or mapping the pilot signal to a set of odd sub-carriers of the first andor last orthogonal frequency division multiplex symbol to generate a frequency-domain pilot signal; and
modulating the frequency-domain pilot signal in the time domain.
3. The method according to claim 2, wherein modulating the frequency-domain pilot signal in the time domain comprises:
performing frequency domain to time domain conversion process on the frequency-domain pilot signal to generate a first time-domain signal, wherein the first time-domain signal is the modulated pilot signal, and the length of the first time-domain signal is less than the length of an orthogonal frequency division multiplex symbol for data transmission, and no less than half the length of data portion in the orthogonal frequency division multiplex symbol for data transmission;
wherein the performing frequency domain to time domain conversion process on the frequency-domain pilot signal to generate the first time-domain signal comprises:
performing frequency domain to time domain conversion on the frequency-domain pilot signal to generate a second time-domain signal, both a first half of the second time-domain signal and a second half of the second time-domain signal carry the pilot signal; and
intercepting a segment of continuous time-domain signal from the second time-domain signal to generate the first time-domain signal, wherein the first time-domain signal comprises the first half of the second time-domain signal or the second half of the second time-domain signal;
wherein the intercepting the segment of continuous time-domain signal from the second time-domain signal to generate the first time-domain signal comprises:
intercepting the segment of continuous time-domain signal from the second time-domain signal, and adding a cyclic prefix before the intercepted segment of continuous time-domain signal to generate the first time-domain signal, wherein the first time-domain signal further comprises the cyclic prefix; or
adding a cyclic prefix before the second time-domain signal, and intercepting the cyclic prefix, and the segment of continuous time-domain signal starting from the starting position of the second time-domain signal to generate the first time-domain signal, wherein the first time-domain signal further comprises the cyclic prefix.
4-6. (canceled)
7. The method according to claim 3, wherein the sub-frame comprises a guard period, and the sum of the length of the first time-domain signal and the length of the guard period is the length in the time domain of the first andor last orthogonal frequency division multiplex symbol of the sub-frame in which the pilot signal is transmitted;
wherein transmitting the modulated pilot signal in the first orthogonal frequency division multiplex symbol in the sub-frame comprises:
transmitting the first time-domain signal in a time domain range from an ending position of the guard period to an ending position of the first orthogonal frequency division multiplex symbol in the sub-frame, wherein a starting position of the guard period is a starting position of the first orthogonal frequency division multiplex symbol in the sub-frame; andor
wherein transmitting the modulated pilot signal in the last orthogonal frequency division multiplex symbol in the sub-frame comprises:
transmitting the first time-domain signal in a time domain range from a starting position of the last orthogonal frequency division multiplex symbol in the sub-frame to a starting position of the guard period, wherein an ending position of the guard period is an ending position of the last orthogonal frequency division multiplex symbol in the sub-frame.
8. (canceled)
9. (canceled)
10. The method according to claim 2, wherein modulating the frequency-domain pilot signal in the time domain comprises:
performing frequency domain to time domain conversion on the frequency-domain pilot signal to generate a second time-domain signal, wherein the second time-domain signal is the modulated pilot signal, and the length of the second time-domain signal is the length in the time domain of the first andlast orthogonal frequency division multiplex symbol in the sub-frame in which the pilot signal is transmitted.
11. A method for receiving a pilot signal, the method comprising:
receiving the modulated pilot signal in a first andor last orthogonal frequency division multiplex symbol of a sub-frame in which the pilot signal is transmitted; and
performing orthogonal frequency division multiplex demodulation on the modulated pilot signal to obtain the pilot signal.
12. The method according to claim 11, wherein performing orthogonal frequency division multiplex demodulation on the modulated pilot signal to obtain the pilot signal comprises:
performing time to frequency conversion on the modulated pilot signal to generate a frequency-domain pilot signal; and
de-mapping the frequency-domain pilot signal, and obtaining the pilot signal from a set of even sub-carriers; or de-mapping the frequency-domain pilot signal, and obtaining the pilot signal from a set of odd sub-carriers.
13. The method according to claim 12, wherein the length of the modulated pilot signal is less than the length of an orthogonal frequency division multiplex symbol for data transmission, and no less than half the length of data portion in the orthogonal frequency division multiplex symbol for data transmission; and the length of the modulated pilot signal is the length in the time domain of the first andor last orthogonal frequency division multiplex symbol in the sub-frame in which the pilot signal is transmitted.
14. (canceled)
15. The method according to claim 13, wherein the sub-frame comprises a guard period, and the sum of the length of the modulated pilot signal and the length of the guard period is the length in the time domain of the first andor last orthogonal frequency division multiplex symbol in the sub-frame in which the pilot signal is transmitted;
wherein receiving the modulated pilot signal in the first orthogonal frequency division multiplex symbol of the sub-frame comprises:
receiving the modulated pilot signal in a time domain range from an ending position of the guard period to an ending position of the first orthogonal frequency division multiplex symbol in the sub-frame, wherein a starting position of the guard period is a starting position of the first orthogonal frequency division multiplex symbol in the sub-frame; andor
wherein receiving the modulated pilot signal in the last orthogonal frequency division multiplex symbol of the sub-frame comprises:
receiving the modulated pilot signal in a time domain range from a starting position of the last orthogonal frequency division multiplex symbol in the sub-frame to a starting position of the guard period, wherein an ending position of the guard period is an ending position of the last orthogonal frequency division multiplex symbol in the sub-frame.
16. (canceled)
17. (canceled)
18. The method according to claim 15, wherein receiving the modulated pilot signal in the first orthogonal frequency division multiplex symbol in the sub-frame comprises:
receiving a modulated pilot signal corresponding to half a second time-domain signal in a time domain range between an ending position of the guard period and an ending position of the first orthogonal frequency division multiplex symbol in the sub-frame, wherein the modulated pilot signal corresponding to half the second time-domain signal is a channel response signal of a first half or second half of the second time-domain signal, the second time-domain signal is obtained by a transmitter performing frequency domain to time domain conversion on the frequency-domain pilot signal, and both the first half of the second time-domain signal and the second half of the second time-domain signal carry the pilot signal; andor
wherein receiving the modulated pilot signal in the last orthogonal frequency division multiplex symbol in the sub-frame comprises:
receiving a modulated pilot signal corresponding to half a second time-domain signal in a time domain range between a starting position of the last orthogonal frequency division multiplex symbol in the sub-frame and a starting position of the guard period, wherein the modulated pilot signal corresponding to half the second time-domain signal is a channel response signal of a first half or second half of the second time-domain signal, the second time-domain signal is obtained by a transmitter performing frequency domain to time domain conversion on the frequency-domain pilot signal, and both the first half of the second time-domain signal and the second half of the second time-domain signal carry the pilot signal.
19. (canceled)
20. (canceled)
21. A pilot signal transmitter, comprising:
a pilot signal modulating module configured to perform orthogonal frequency division multiplex modulation on a pilot signal; and
a pilot signal transmitting module configured to transmit the modulated pilot signal in a first andor last orthogonal frequency division multiplex symbol of a sub-frame in which the pilot signal is transmitted.
22. The transmitter according to claim 21, wherein the pilot signal modulating module is configured:
to map the pilot signal to a set of even sub-carriers of the first andor last orthogonal frequency division multiplex symbol to generate a frequency-domain pilot signal; or to map the pilot signal to a set of odd sub-carriers of the first andor last orthogonal frequency division multiplex symbol to generate a frequency-domain pilot signal; and
to modulate the frequency-domain pilot signal in the time domain.
23. The transmitter according to claim 22, wherein the pilot signal modulating module configured to modulate the frequency-domain pilot signal in the time domain is configured:
to perform frequency domain to time domain conversion on the frequency-domain pilot signal to generate a first time-domain signal, wherein the first time-domain signal is the modulated pilot signal, and the length of the first time-domain signal is less than the length of an orthogonal frequency division multiplex symbol for data transmission, and no less than half the length of data portion in the orthogonal frequency division multiplex symbol for data transmission;
wherein the pilot signal modulating module configured to perform frequency domain to time domain conversion on the frequency-domain pilot signal to generate the first time-domain signal is configured:
to perform frequency domain to time domain conversion on the frequency-domain pilot signal to generate a second time-domain signal, both a first half of the second time-domain signal and a second half of the second time-domain signal carry the pilot signal; and
to intercept a segment of continuous time-domain signal from the second time-domain signal to generate the first time-domain signal, wherein the first time-domain signal comprises the first half of the second time-domain signal or the second half of the second time-domain signal;
wherein the pilot signal modulating module configured to intercept the segment of continuous time-domain signal from the second time-domain signal to generate the first time-domain signal is configured:
to intercept the segment of continuos time-domain signal from the second time-domain signal, and to add a cyclic prefix before the intercepted segment of continuous time-domain signal to generate the first time-domain signal, wherein the first time-domain signal further comprises the cyclic prefix; or
to add a cyclic prefix before the second time-domain signal, and to intercept the cyclic prefix, and the segment of continuous time-domain signal starting from the starting position of second time-domain signal to generate the first time-domain signal, wherein the first time-domain signal further comprises the cyclic prefix.
24-26. (canceled)
27. The transmitter according to claim 23, wherein the sub-frame comprises a guard period, and the sum of the length of the first time-domain signal and the length of the guard period is the length in the time domain of the first andor last orthogonal frequency division multiplex symbol of the sub-frame in which the pilot signal is transmitted;
wherein the pilot signal transmitting module configured to transmit the modulated pilot signal in the first orthogonal frequency division multiplex symbol in the sub-frame is configured: to transmit the first time-domain signal in a time domain range from an ending position of the guard period to an ending position of the first orthogonal frequency division multiplex symbol in the sub-frame, wherein a starting position of the guard period is a starting position of the first orthogonal frequency division multiplex symbol in the sub-frame; andor
wherein the pilot signal transmitting module configured to transmit the modulated pilot signal in the last orthogonal frequency division multiplex symbol in the sub-frame is configured:
to transmit the first time-domain signal in a time domain range from a starting position of the last orthogonal frequency division multiplex symbol in the sub-frame to a starting position of the guard period, wherein an ending position of the guard period is an ending position of the last orthogonal frequency division multiplex symbol in the sub-frame.
28. (canceled)
29. (canceled)
30. The transmitter according to claim 22, wherein the pilot signal modulating module configured to modulate the frequency-domain pilot signal in the time domain is configured:
to perform frequency domain to time domain conversion on the frequency-domain pilot signal to generate a second time-domain signal, wherein the second time-domain signal is the modulated pilot signal, and the length of the second time-domain signal is the length in the time domain of the first andlast orthogonal frequency division multiplex symbol in the sub-frame in which the pilot signal is transmitted.
31. A pilot signal receiver, comprising:
a pilot signal receiving module configured to receive a modulated pilot signal in a first andor last orthogonal frequency division multiplex symbol of a sub-frame in which the pilot signal is transmitted; and
a pilot signal demodulating module configured to perform orthogonal frequency division multiplex demodulation on the modulated pilot signal to obtain the pilot signal.
32. The receiver according to claim 31, wherein the pilot signal demodulating module is configured:
to perform time to frequency conversion on the modulated pilot signal to generate a frequency-domain pilot signal; and
to de-map the frequency-domain pilot signal, and to obtain the pilot signal from a set of even sub-carriers; or to de-map the frequency-domain pilot signal, and to obtain the pilot signal from a set of odd sub-carriers.
33. The receiver according to claim 32, wherein the length of the modulated pilot signal is less than the length of an orthogonal frequency division multiplex symbol for data transmission, and no less than half the length of data portion in the orthogonal frequency division multiplex symbol for data transmission; and the length of the modulated pilot signal is the length in the time domain of the first andor last orthogonal frequency division multiplex symbol in the sub-frame in which the pilot signal is transmitted.
34. (canceled)
35. The receiver according to claim 33, wherein the sub-frame comprises a guard period, and the sum of the length of the modulated pilot signal and the length of the guard period is the length in the time domain of the first andor last orthogonal frequency division multiplex symbol in the sub-frame in which the pilot signal is transmitted;
wherein the pilot signal receiving module configured to receive the modulated pilot signal in the first orthogonal frequency division multiplex symbol of the sub-frame is configured: to receive the modulated pilot signal in a time domain range from an ending position of the guard period to an ending position of the first orthogonal frequency division multiplex symbol in the sub-frame, wherein a starting position of the guard period is a starting position of the first orthogonal frequency division multiplex symbol in the sub-frame; andor
the pilot signal receiving module configured to receive the modulated pilot signal in the last orthogonal frequency division multiplex symbol of the sub-frame is configured: to receive the modulated pilot signal in a time domain range from a starting position of the last orthogonal frequency division multiplex symbol in the sub-frame to a starting position of the guard period, wherein an ending position of the guard period is an ending position of the last orthogonal frequency division multiplex symbol in the sub-frame.
36. (canceled)
37. (canceled)
38. The receiver according to claim 35, wherein the pilot signal receiving module configured to receive the modulated pilot signal in the first orthogonal frequency division multiplex symbol in the sub-frame is configured:
to receive a modulated pilot signal corresponding to half a second time-domain signal in a time domain range between an ending position of the guard period and an ending position of the first orthogonal frequency division multiplex symbol in the sub-frame, wherein the modulated pilot signal corresponding to half the second time-domain signal is a channel response signal of a first half or second half of the second time-domain signal, the second time-domain signal is obtained by a transmitter performing frequency domain to time domain conversion on the frequency-domain pilot signal, and both the first half of the second time-domain signal and the second half of the second time-domain signal carry the pilot signal; andor
the pilot signal receiving module configured to receive the modulated pilot signal in the last orthogonal frequency division multiplex symbol in the sub-frame is configured:
to receive a modulated pilot signal corresponding to half a second time-domain signal in a time domain range between a starting position of the last orthogonal frequency division multiplex symbol in the sub-frame and a starting position of the guard period, wherein the modulated pilot signal corresponding to half the second time-domain signal is a channel response signal of a first half or second half of the second time-domain signal, the second time-domain signal is obtained by a transmitter performing frequency domain to time domain conversion on the frequency-domain pilot signal, and both the first half of the second time-domain signal and the second half of the second time-domain signal carry the pilot signal.
39. (canceled)
40. (canceled)
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound having the formula:
or a salt thereof.
2. The compound of having the formula:
3. The crystalline form of the compound claim 2, wherein the crystalline form is the N-1 Form.
4. The crystalline form of claim 3, wherein the N-1 Form is characterized by unit cell parameters substantially equal to the following:
Cell dimensions:
a=7.3085(6)
b=16.257(1)
c=22.688(2)
\u03b1\xb0=90
\u03b2\xb0=90
\u03b3\xb0=90
Space group P212121
Moleculesunit cell (Z): 1
Density, calc g-cm\u22123: 1.194
wherein said crystal is at a temperature of about \u221270\xb0 C.
5. The crystalline form as defined in claim 3 as characterized by a powder x-ray diffraction pattern substantially in accordance with that shown in FIG. 1.
6. The crystalline form as defined in claim 3 which is characterized by a differential scanning calorimetry thermogram substantially in accordance with that shown in FIG. 2, having an endothermic transition above ca. 205\xb0 C.
7. The crystalline form as defined in claim 3 which is characterized by a thermal gravimetric analysis curve in accordance with that shown in FIG. 3.
8. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable carrier.
9. The pharmaceutical composition of claim 8 further comprising at least one additional therapeutic agent.
10. A pharmaceutical composition comprising the compound of claim 2 and a pharmaceutically acceptable carrier.
11. The pharmaceutical composition of claim 10 further comprising at least one additional therapeutic agent.
12. A compound having the formula:
or a salt thereof.
13. A pharmaceutical composition comprising the compound of claim 12 and a pharmaceutically acceptable carrier.
14. The pharmaceutical composition of claim 13 further comprising at least one additional therapeutic agent.
15. A process for preparing N-((1R,2S,5R)-5-(tert-butylamino)-2((S)-3-(7-tert-butylpyrazolo 1,5-a1,3,5triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide comprising the process set forth in the following scheme: