1. A computer implemented method for associating an advertisement with a search result, comprising:
receiving from a search request user an activity keyword for performing a computer implemented search, wherein the search request user has a social network account that allows the social network user to form relationships by invitation with other social network users and to share private social network data on the social network through the relationships;
providing a first database stored on a tangible medium, the database storing activities associated with geographic locations, wherein the first database includes activity terms derived from private social network data having permission rules associated therewith that restrict access of the private social network data to particular members of the social network;
searching the first database using the activity keyword to identify an activity in the database related to the activity keyword;
generating a search result based on the identified activity;
identifying a geographic location associated with the identified activity;
using the identified geographic location associated with the identified activity to select one or more advertisements; and
sending the one or more selected advertisements with the search result to an electronic device of the search request user.
2. The method of claim 1, wherein the one or more advertisements relate to an activity different than the activity keyword.
3. The method of claim 1, wherein the social network data is from a social network having at least 1 million users.
4. The method of claim 1, wherein the association of at least a portion of the activities to the geographic locations in the first database is derived from social network data.
5. The method of claim 4, wherein the association derived from the social network data is derived from private social network data.
6. The method of claim 1, wherein the advertisement is selected at least in part based on private social network data.
7. The method of claim 6, wherein the social network data is from a social network having at least 1 million users.
8. The method of claim 1, further comprising receiving authentication data from the social network user for accessing the private social network data on the social network user account.
9. The method of claim 6, wherein the private social network data used to select the advertisement includes a social network relationship with the search request user.
10. The method of claim 6, wherein the private social network data used to select the advertisement is derived from text or pictures posted on the social network.
11. The method of claim 10, wherein the text or pictures are provided to the social network by the search request user.
12. The method of claim 1, further comprising providing a search results list to the search request user.
13. The method of claim 12, wherein the search results list includes selectable links to the first database andor a second database.
14. The method of claim 13, wherein the search results list includes selectable links to private social network data and to non-social network data publicly available on the World Wide Web.
15. The method of claim 1, wherein the activity keyword is a participle.
16. A system comprising one or more computers configured to perform the method of claim 1.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. Supra molecular self-assemblies of a polyelectrolyte for use in combination with a pharmacological ingredient, comprising:
at least one polyelectrolyte compound selected from the group consisting of diblock copolymers, multiblock copolymers and graft copolymers,
said diblock and multiblock copolymers including at least two blocks one of which is hydrophilic and essentially uncharged, and another of which contains at least one repeating unit selected from the group consisting of anionizable or permanently-negatively charged repeating units in combination with essentially hydrophobic repeating units,
said graft copolymers comprising grafted hydrophilic and essentially non-ionic oligomers or polymers, and including anionizable units, permanently-negatively charged units or mixtures of anionizable and permanently-negatively charged units, in combinaison with essentially hydrophobic repeating units,
wherein a polyelectrolyte segment forms a core of the assembly and chemically bears non-ionic hydrophobic repeating units.
2. The supramolecular self-assemblies of claim 1, wherein:
said anionizable units are repeating units that can be transformed from a non-ionic to a negatively charged state via an external stimulus.
3. The supramolecular self-assemblies of claim 2, wherein:
said external stimulus is selected from the group consisting of a change in pH, ionic strength, temperature or other physico-chemical changes.
4. The supramolecular self-assemblies of claim 1, wherein:
said anionizable or permanently-negatively charged block, bearing hydrophobic repeating units, is synthesized from at least one hydrophobic compound selected from the group consisting of vinyl monomers, vinyl oligomers, and vinyl polymers.
5. The supramolecular self-assemblies of claim 4, wherein:
said hydrophobic compound is at least one compound selected from the group consisting of acrylate, acrylamide, alkylacrylate, alkylacrylamide, arylacrylate and arylacrylamide derivatives.
6. The supramolecular self-assemblies of claim 5, wherein:
said alkyl or aryl derivatives include at least one aliphatic or aromatic moiety selected from the group consisting of acrylate, acrylamide, methacrylate and methacrylamide derivatives.
7. The supramolecular self-assemblies of claim 4, wherein:
said hydrophobic compound is at least one vinyl-terminated biodegradable polyester.
8. The supramolecular self-assemblies of claim 7, wherein:
said vinyl terminated biodegradable polyester is selected from the group consisting of vinyl-terminated poly(lactide) and vinyl-terminated poly \u03b5-caprolactone).
9. The supramolecular self-assemblies of claim 1, wherein:
said anionizable units include at least one functional group selected from carboxylate, phosphate and sulfate.
10. The supramolecular self-assemblies of claim 1, wherein:
said hydrophilic block is synthesized from at least one hydrophilic compound selected from vinyl monomers, vinyl oligomers and vinyl polymers.
11. The supramolecular self-assemblies of claim 10, wherein:
said hydrophilic compound is at least one compound selected from the group consisting of acrylate derivatives, acrylamide derivatives, alkylacrylate derivatives, alkylacrylamide, and N-vinyl-2-pyrrolidone derivatives.
12. The supramolecular self-assemblies of claim 1, wherein:
said hydrophilic block originates from a macroinitiator based on poly (ethylene glycol) or poly (N-vinyl-2-pyrrolidone).
13. A pharmaceutical formulation comprising supramolecular self-assemblies of claim 1 in combination with a effective amount of at least one pharmacological constituent.
14. The pharmaceutical formulation of claim 13, wherein the pharmacological constituent is a drug.
15. The pharmaceutical formulation of claim 13, wherein the pharmacological constituent is a peptide, protein or genetic material.
16. The pharmaceutical formulation of claim 13, including a targeting ligand.