1. A method for preparing a spherical support for olefin catalysts, which comprises reacting metal magnesium with an alcohol in the presence of a reaction initiator, characterized in that the reaction initiator is a halogenated nitrogen compound selected from the group consisting of the compounds represented by the following general formulas I-IV, wherein the halogenated nitrogen compound is used at the amount of 0.001-0.2 parts by weight, based on 1 part by weight of the metal magnesium, and the alcohol is used at the amount of 5-50 parts by weight, based on 1 part by weight of the metal magnesium:
wherein, X refers to halogen, and R1, R2, R3 and R4 are independently hydrogen, or alkyl or aryl having C1-12;
wherein, X refers to halogen;
wherein, x refers to halogen, and R1, R2, R3 and R4 are independently hydrogen, or alkyl or aryl having C1-12;
wherein, x refers to halogen, and R1 and R2 are independently hydrogen, or alkyl or aryl having C1-12.
2. The method for preparing a spherical support for olefin polymerization catalysts according to claim 1, wherein the alcohol is at least one selected from the group consisting of aliphatic alcohols represented by the general formula ROH, wherein R is an alkyl having 1-6 carbon atoms, and aromatic alcohols.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An implantable cardiac stimulation device comprising:
a first lead adapted to be implanted in or on the heart of a patient, wherein the first lead comprises a long axis and a first mechanical sensor positioned along the long axis, the first mechanical sensor configured to obtain measurements indicative of physical contraction and relaxation of the walls of the heart during systole and diastole, wherein the first lead is adapted to be implanted with its long axis at least partially around the basal region of the heart;
a second lead adapted to be implanted in or on the heart of a patient, wherein the second lead comprises a long axis and a second mechanical sensor positioned along the long axis, the second mechanical sensor configured to obtain measurements indicative of physical contraction and relaxation of the walls of the heart during systole and diastole, wherein the second lead is adapted to be implanted with its long axis at least partially around the apical region of the heart; and
a controller configured to receive signals from the first mechanical sensor and the second mechanical sensor indicative of contraction and relaxation of the walls of the heart, calculate a basal rotational velocity index based on the signals received from the first mechanical sensor, calculate an apical rotational velocity index based on the signals received from the second mechanical sensor, and derive a torsion index based on the basal rotational velocity index and the apical rotational velocity index.
2. The device of claim 1 wherein each of the first mechanical sensor and the second mechanical sensor comprises a cardiomechanical electric sensor material (CMES) configured to contact myocardial tissue at two points separated by a distance x.
3. The device of claim 2 wherein the controller is configured to calculate the basal velocity index based on the distance x and changes in the signals received from the first mechanical sensor as a function of time (dCMESdt).
4. The device of claim 1 wherein the first mechanical sensor is adapted to be positioned in one of the proximal to lateral portion of the main coronary sinus branch, the atrioventricular groove and the atrioventricular ring.
5. The device of claim 1 wherein the second mechanical sensor is adapted to be positioned in pericardial space around the apex of the heart.
6. The device of claim 2 wherein the controller is configured to calculate the apical velocity index based on the distance x and changes in the signals received from the second mechanical sensor as a function of time (dCMESdt).
7. The device of claim 1 wherein the torsion index is a summation of the basal rotational velocity index and the apical rotational velocity index.
8. The device of claim 1 wherein the at least one of the first mechanical sensor and the second mechanical sensor runs in a helical fashion along the long axis of the respective first lead or second lead.
9. The device of claim 1 wherein the at least one of the first mechanical sensor and the second mechanical sensor comprises a material embedded parallel to the long axis of the respective first lead or second lead.
10. The device of claim 1 wherein the controller is further configured to monitor changes in the torsion index over time as an indication of heart failure status.