1. An intraoral inspection apparatus comprising:
a light source unit which is provided with color-producing light sources capable of inducing fluorescent lights from diseased sites by irradiating an oral cavity;
a wavelength adjusting device which is provided with a first filter that transmits, among the fluorescent lights, a light having a wavelength of a fluorescent light from a predetermined diseased site and blocks or attenuates a light having a wavelength other than this wavelength, and provided with a second filter that transmits, among the fluorescent lights, a light having a wavelength of a fluorescent light from a diseased site different from the predetermined diseased site and blocks or attenuates a light having a wavelength other than this wavelength; and
an imaging device which receives the fluorescent light transmitted through the first filter and the fluorescent light transmitted through the second filter, and converts them into electrical signals.
2. The intraoral inspection apparatus according to claim 1, further comprising a white light source.
3. The intraoral inspection apparatus according to claim 1, wherein a first QLF mode and a second QLF mode are switched automatically or manually,
the first QLF mode being a mode in which the color-producing light sources are turned on and the first filter is disposed such that the light transmitted through the first filter is received by the imaging device, and
the second QLF mode being a mode in which the color-producing light sources are turned on and the second filter is disposed such that the light transmitted through the second filter is received by the imaging device.
4. A method for operating an intraoral inspection apparatus, wherein the intraoral inspection apparatus according to claim 1 is used;
the color-producing light source is turned on, a light from the color-producing light source is irradiated into the oral cavity, and the light from the oral cavity is received by the imaging device through the first filter;
the color-producing light source is turned on, a light from the color-producing light source is irradiated into the oral cavity, and the light from the oral cavity is received by the imaging device through the second filter.
5. A method for operating an intraoral inspection apparatus, wherein the intraoral inspection apparatus according to claim 2 is used;
the color-producing light source is turned on, a light from the color-producing light source is irradiated into the oral cavity, and the light from the oral cavity is received by the imaging device through the first filter;
the color-producing light source is turned on a light from the color-producing light source is irradiated into the oral cavity, and the light from the oral cavity is received by the imaging device through the second filter; and
the white light source is turned on and a light from the oral cavity is received by the imaging device.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. An automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof, the device comprising:
a housing assembly having an interior chamber, the interior chamber including a wet compartment containing a wet medicament component;
a seal structure placed at an orifice of the interior chamber, the seal structure being initially in a sealing condition that maintains the wet component within the interior chamber, the seal structure being converted to a mixing condition as a result of activation of the device;
a mixing assembly comprised of at least one microfluidic channel, in fluid communication with the interior chamber when the device is activated, and wherein a portion of the mixing assembly contains a dry medicament component configured to mix with the wet medicament component when the seal structure is converted to mixing condition;
a delivery assembly that dispenses the charge of medicament from the housing;
an activation assembly carried by the housing and including a stored energy source, wherein activation of the activation assembly releases the stored energy from the stored energy source, and wherein the release of the stored energy causes a) the seal structure to be converted from the sealing condition to the mixing condition and thereby permit the wet component to pass there through, b) the wet component to be forced through the mixing assembly to facilitate mixing of the wet and dry components, and c) force the mixed components through the delivery assembly.
2. The automatic injection device of claim 1, wherein the dry component is partially soluble in the wet component
3. The automatic injection device of claim 1, wherein the microfluidic channel of the mixing device includes a plurality of grooves formed therein, wherein said grooves facilitate chaotic flow when a wet component flows by said grooves.
4. The automatic injection device of claim 1, wherein the microfluidic channel of the mixing device includes a plurality of bends.
5. The automatic injection device of claim 1, wherein the microfluidic channel of the mixing device includes internal structures.
6. The automatic injection device of claim 1, further including a homogenizing region in fluid communication with the mixing device.
7. The automatic injection device of claim 1, wherein a portion of the microfluidic channel contains a lyophilized dry medicament.
8. The automatic injection device of claim 7, wherein the lyophilized dry medicament is an epinephrine component or any salt-based form thereof.
9. The automatic injection device of claim 1, wherein the mixing device further includes a plurality of microfluidic channels.
10. The automatic injection device of claim 1, further including a safety cap removably inserted into the housing assembly, wherein the device may not be activated until the safety cap is removed from the housing assembly.
11. The automatic injection device of claim 1, wherein the stored energy source is a compressed spring.
12. The automatic injection device of claim 1, wherein the interior chamber is configured to collapse upon activation.
13. The automatic injection device of claim 1, further including a trigger assembly configured to release the stored energy source when activated.
14. The automatic injection device of claim 1, wherein one-dimension of the cross-section of the microfluidic channel is less than two millimeters across.
15. The automatic injection device of claim 1, wherein one-dimension of the cross-section of the microfluidic channel is less than one millimeter across.
16. The automatic injection device of claim 1, wherein no dimension of the cross-section of the microfluidic channel is greater than a millimeter.
17. The automatic injection device of claim 9, further including a controllable valve configured to allow access to each microfluidic channel.
18. A method of administering a medicament comprising the steps of:
Activating a pre-loaded automatic injection device near a person, wherein the automatic injection device is comprised of:
a housing assembly having an interior chamber, the interior chamber including a wet compartment containing a wet medicament component,
a seal structure placed at an orifice of the interior chamber, the seal structure being initially in a sealing condition that maintains the wet component within the interior chamber, the seal structure being converted to a mixing condition as a result of activation of the device,
a mixing assembly comprised of at least one microfluidic channel, in fluid communication with the interior chamber when the device is activated, and wherein a portion of the mixing assembly contains a dry medicament component configured to mix with the wet medicament component when the seal structure is converted to mixing condition,
a delivery assembly that dispenses the charge of medicament from the housing,
an activation assembly carried by the housing and including a stored energy source, wherein activation of the activation assembly releases the stored energy from the stored energy source, and wherein the release of the stored energy causes a) the seal structure to be converted from the sealing condition to the mixing condition and thereby permit the wet component to pass there through, b) the wet component to be forced through the mixing assembly to facilitate mixing and dissolution of the dry medicament component in the liquid component, and c) force the mixed wet and dry components through the delivery assembly,
wherein a portion of the delivery assembly is inserted into the person upon activation, and
wherein the mixed components are injected into the person through the delivery assembly.
19. The automatic injection device of claim 18, wherein the microfluidic channel of the mixing device includes a plurality of grooves formed therein, wherein said grooves facilitate chaotic flow when a wet component flows by said grooves.
20. The automatic injection device of claim 18, wherein the microfluidic channel of the mixing device includes a plurality of bends.
21. The automatic injection device of claim 18, further including a homogenizing region in fluid communication with the mixing device.
22. The automatic injection device of claim 18, wherein a portion of the microfluidic channel contains a lyophilized dry medicament component.
23. The automatic injection device of claim 18, wherein the mixing device further includes a plurality of microfluidic channels.
24. The automatic injection device of claim 18, further including a safety cap removably inserted into the housing assembly, wherein the device may not be activated until the safety cap is removed from the housing assembly.
25. The automatic injection device of claim 18, wherein the stored energy source is a compressed spring.
26. The automatic injection device of claim 18, wherein the interior chamber is configured to collapse upon activation.
27. The automatic injection device of claim 18, further including a trigger assembly configured to release the stored energy source when activated.
28. The automatic injection device of claim 18, wherein one-dimension of the cross-section of the microfluidic channel is less than one millimeter across.
29. The automatic injection device of claim 18, wherein no dimension of the cross-section of the microfluidic channel is greater than a millimeter.
30. A method of assembling an automatic injection device comprising the steps of:
filling an interior chamber with a first wet component;
sealing the interior chamber with a seal;
inserting a dry component into a portion of a mixing assembly configured to be in fluid communication with the interior chamber upon activation of the seal;
and
attaching the interior chamber and mixing assembly to a delivery assembly.
31. The method of claim 30, wherein the inserting a dry component step is comprised of:
inserting a wet component to be dried into a portion of the mixing assembly; and
lyophilizing the wet component to be dried inside the mixing assembly, wherein the wet component to be dried becomes a dry component;
32. The method of claim 30, wherein the inserting a dry component step further comprises:
spray drying the dry component into a portion of the mixing assembly.
33. The method of claim 30, wherein the inserting a dry component step further comprises:
vacuum drying the dry component into a portion of the mixing assembly.
34. The method of claim 30, wherein the inserting a dry component step further comprises:
powder filling the dry component into a portion of the mixing assembly.
35. The method of claim 30, wherein the mixing assembly is comprised of at least one microfluidic channel.
36. A medicament mixing device comprising:
a housing assembly having at least one interior chamber, the interior chamber including a wet compartment containing a wet medicament component;
a seal structure placed at an orifice of the interior chamber, the seal structure being initially in a sealing condition that maintains the wet component within the interior chamber, the seal structure being converted to a mixing condition as a result of activation of the device;
a mixing assembly comprised of at least one microfluidic channel, in fluid communication with the interior chamber when the device is activated, and wherein a portion of the mixing assembly contains a dry medicament component configured to mix with the wet medicament component when the seal structure is converted to a mixing condition.
37. The mixing device of claim 36, further including internal structures contained within the microfluidic channel.