1. A method comprising:
receiving, via a mobile media device, a plurality of audio content from a plurality of channels obtained from a variety of content providers;
monitoring output of the plurality of audio content by the mobile media device; and
displaying in a user interface on a display device of the mobile media device, for each of the plurality of audio content that was previously output, a description of the previously output audio content, a description of the particular channel of the plurality of channels from which the previously output audio content was received, and a description of the particular content provider from which the particular channel was obtained.
2. A method as described in claim 1, wherein a portion of the user interface that describes a particular said audio content is selectable to initiate an operation to purchase the particular said audio content via a network connection.
3. A method as described in claim 2, wherein the particular said audio content once purchased is downloadable by another media device.
4. A method as described in claim 2, wherein the operation includes authenticating a user of the mobile media device using an authentication service.
5. A method as described in claim 4, wherein the authentication of the user by the authentication service provides access to a plurality of websites, at least one of which is configured to provide the particular said audio content for purchase.
6. A method as described in claim 4, wherein the authentication of the user by the authentication service is performed automatically and without user intervention using a token that is stored on the mobile media device.
7. A method as described in claim 1, wherein a first one of the plurality of channels is received using frequency modulation (FM) and a second one of the plurality of channels is received via satellite.
8. A method as described in claim 1, wherein the user interface describes each of the plurality of audio content using metadata received with respective said audio content.
9. A method as described in claim 1, wherein the user interface describes the plurality of audio content in reverse chronological order of when each of the plurality of audio content was output, respectively.
10. A mobile media device comprising:
a display device; and
one or more modules configured to perform operations comprising:
receiving wirelessly, via the mobile media device, a plurality of audio content from a plurality of channels obtained from a variety of sources;
outputting the plurality of audio content that has been wirelessly received via the plurality of channels obtained from the variety of sources; and
displaying a user interface in a single screen on the display device that includes one or more of the audio content that is an advertisement, the user interface configured to display a summary of user navigation among each of one or more channels of the plurality of channels by describing for each said audio content, the audio content, a particular channel of the one or more channels associated with the audio content, and a particular one of the variety of sources that provided the audio content.
11. The mobile media device as described in claim 10, wherein:
the one or more modules are configured to receive the one or more of the audio content that is an advertisement wirelessly via a one-way broadcast; and
the description of the advertisement is selectable in the user interface to navigate to the advertisement that is accessible by the one or more modules via a two-way network connection.
12. The mobile media device as described in claim 11, wherein the two-way network connection provides an Internet connection and the one-way broadcast is received via a radio broadcast in compliance with frequency modulation (FM).
13. The mobile media device as described in claim 11, wherein the description of the advertisement in the user interface includes metadata that was received with the advertisement.
14. The mobile media device as described in claim 10, wherein the description of the advertisement is selectable in the user interface to navigate to the advertisement via an Internet connection to purchase a good or service that pertains to the advertisement.
15. One or more computer-readable storage comprising instructions that are executable by a mobile media device to output a user interface that describes a plurality of content received via a plurality of channels from a plurality of sources and output by the mobile media device, the user interface having one or more options to purchase the plurality of content for download, the user interface configured to provide a summary of user-navigation by describing each of the plurality of channels and from which of the plurality of sources the content was received from, each associated with a respective one of a plurality of content described in the user interface in a single screen and output by the mobile media device.
16. The one or more computer-readable storage as described in claim 15, wherein the mobile media device is installed in a vehicle.
17. The one or more computer-readable storage as described in claim 15, wherein the plurality of sources includes a one-way broadcast and a two-way network connection, and the plurality of content includes audio content that was received via an FM broadcast and audio content that was received via a satellite broadcast.
18. The one or more computer-readable storage as described in claim 15, wherein the user interface describes the plurality of content in reverse chronological order of when each of the plurality of audio content was output, respectively, by the mobile media device.
19. The one or more computer-readable storage as described in claim 15, wherein the user interface describes the plurality of content in groups arranged by source.
20. The one or more computer-readable storage as described in claim 15, wherein the user interface has one or more options to purchase the plurality of content for download to and local storage by the mobile media device.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1-13. (canceled)
14. A contrast agent for MRI imaging comprising:
one cyclodextrin, whose truncated-cone-shaped structure defines a central axis, a first and a second openings along said axis,
one paramagnetic element, located on said cyclodextrin axis, outside said structure and proximate to the first opening,
one or several coordination ligand(s) of the paramagnetic element which coordinate(s) said paramagnetic element,
one arm of formula
-A
covalently bound to the cyclodextrin, proximate to the second opening,
wherein A is a carbon group able to form an inclusion complex with the cyclodextrin.
15. A bioactivable contrast agent for MRI imaging comprising:
one cyclodextrin, whose truncated-cone-shaped structure defines a central axis, a first and a second openings along said axis,
one paramagnetic element, located on said cyclodextrin axis, outside said structure and proximate to the first opening,
one or several coordination ligand(s) of the paramagnetic element which coordinate(s) said paramagnetic element,
one mobile arm of formula
-A-X
covalently bound to the cyclodextrin, proximate to the second opening,
wherein X is a cleavable biometabolizable moiety,
A is a spacer between the cyclodextrin and X, wherein A is a carbon group able to form an inclusion complex with the cyclodextrin.
16. The MRI contrast agent according to claim 14, wherein the cyclodextrin is selected in the group consisting of alpha-cyclodextrin, beta-cyclodextrin and gamma-cyclodextrin.
17. The MRI contrast agent according to claim 16, wherein the cyclodextrin is a beta-cyclodextrin.
18. The MRI contrast agent according to claim 14, wherein the paramagnetic element is selected from the group consisting of lanthanides such as gadolinium and dysprosium; transition metals such as manganese, iron, cobalt, and chromium; and magnesium.
19. The MRI contrast agent according to claim 18, wherein the paramagnetic element is gadolinium.
20. The MRI contrast agent according to claim 14, wherein the first opening is the smallest opening of the cyclodextrin.
21. The MRI contrast agent according to claim 14, wherein the coordination ligand(s) correspond(s) to formula V:
22. The MRI contrast agent according to claim 14, wherein the coordination ligand(s) correspond(s) to formula XI:
23. The MRI contrast agent according to claim 14, wherein the coordination ligand(s) correspond(s) to formula I:
wherein R and R\u2032 are independently hydrogen or an alkyl chain,
Z is NR or O,
Y is CO2\u2212, PO32\u2212 or SO32\u2212.
24. The MRI contrast agent according to claim 15, wherein the cleavable biometabolizable moiety X comprises a peptidic sequence.
25. Method of acquiring an image, comprising:
a) the administration of the contrast agent according to claim 14 to a tissue, cell or patient, and
b) the acquisition of a magnetic resonance image of said cell, tissue or patient.
26. The method according to claim 25, comprising administering a composition comprising said contrast agent and a pharmaceutically acceptable carrier.
27. The MRI contrast agent according to claim 15, wherein the cyclodextrin is selected in the group consisting of alpha-cyclodextrin, beta-cyclodextrin and gamma-cyclodextrin.
28. The MRI contrast agent according to claim 27, wherein the cyclodextrin is a beta-cyclodextrin.
29. The MRI contrast agent according to claim 15, wherein the paramagnetic element is selected from the group consisting of lanthanides such as gadolinium and dysprosium; transition metals such as manganese, iron, cobalt, and chromium; and magnesium.
30. The MRI contrast agent according to claim 29, wherein the paramagnetic element is gadolinium.
31. The MRI contrast agent according to claim 15, wherein the first opening is the smallest opening of the cyclodextrin.
32. The MRI contrast agent according to claim 15, wherein the coordination ligand(s) correspond(s) to formula V:
33. The MRI contrast agent according to claim 15, wherein the coordination ligand(s) correspond(s) to formula XI:
34. The MRI contrast agent according to claim 15, wherein the coordination ligand(s) correspond(s) to formula I:
wherein R and R\u2032 are independently hydrogen or an alkyl chain,
Z is NR or O,
Y is CO2\u2212, PO32\u2212 or SO32\u2212.
35. Method of acquiring an image, comprising:
a) the administration of the contrast agent according to claim 15 to a tissue, cell or patient, and
b) the acquisition of a magnetic resonance image of said cell, tissue or patient.
36. The method according to claim 35, comprising administering a composition comprising said contrast agent and a pharmaceutically acceptable carrier.