1. A compound having the formula
wherein:
A=counter-ion
a=1-3
b=0-3
X=1-6C alkyl or heteroalkyl
R1=1-6C alkyl
one of R2 and R3 is alkyl and the other is XN+Hb(R1)3-b, or R2 and R3 form a methylene dioxy group
one of R4 and R5 is halogen and the other is halogen substituted 1-6C alkyl,
one or both of R4 and R5 are XN+Hb(R1)3-b, or R4 and R5 are joined to form an aromatic or a hetero aromatic ring or a substituted aromatic ring
or substituted hetero aromatic ring.
2. The compound of claim 1 having the formula
wherein:
A=counter-ion
X=1-6C alkyl
a=1-3
b=0-3
R1=1-3C alkyl
one of R2 and R3 is 1-4C alkyl and the other is XN+Hb(R1)3-b, or R2 and R3 form a methylene dioxy group
R4\u2550CHF2
R5=Halogen.
3. The compound of claim 2, wherein
X is propyl
b is zero
R1 is methyl
R2 and R3 form a methylene dioxy group
R4 is CHF2
R5 is Cl.
4. The compound of claim 2, wherein
X is propyl
b is 1
R1 is methyl
R2 and R3 form a methylene dioxy group
R4 is CHF2
R5 is Cl.
5. The compound of claim 2, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methoxy
R4 is CHF2
R5 is Cl.
6. The compound of claim 1 having the formula
wherein:
a=1-3
A=counter-ion
X=1-6C alkyl
b=0-3
R1=1-3C alkyl
one of R2 and R3 is alkyl and the other is XN+Hb(R1)3-b, or R2 and R3 form a methylene dioxy group
one of R4 and R5 is halogen and the other is a halogen substituted 1-6C alkyl, or R4 and R5 are hydrogen
R6=1-4C alkoxy, hydrogen, or halogen.
7. The compound of claim 6, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methoxy.
R4, R5, and R6 are hydrogen.
8. The compound of claim 6, wherein
X is propyl
R1 is methyl
b is zero
R2 is trimethylammonium propyl
R3 is methyl
R4 and R5 form an aromatic ring
R6 is methoxy.
9. The compound of claim 6, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methyl
R4 and R5 are hydrogen
R6 is ethoxy.
10. The compound of claim 6, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methyl
R4 and R5 are hydrogen
R6 is bromine.
11. The compound of claim 1, wherein said at least one counter-ion is nitrite, phosphate, hydrogenphosphate, dihydrogen phosphate, hydrogen sulfate, sulfate, hydrogen carbonate, carbonate, methane sulfonate, fluoroborate, bromide, chloride, iodide, or combinations thereof.
12. A method of measuring an analyte contained in a biological fluid, the analyte adapted to produce a proportional color change upon a reaction, the method comprising the acts of:
providing a tetrazolium salt as an indicator, said tetrazolium salt having the formula of
wherein:
A=counter-ion
a=1-3
b=0-3
X=1-6C alkyl or heteroalkyl
R1=1-6C alkyl
one of R2 and R3 is alkyl and the other is XN+Hb(R1)3-b, or R2 and R3 form a methylene dioxy group
one of R4 and R5 is halogen and the other is a halogen substituted 1-6C alkyl, one or both of R4 and R5 are XN+Hb(R1)3-b, or R4 and R5 are joined to form an aromatic or a hetero aromatic ring or a substituted aromatic ring or substituted hetero aromatic ring; and
determining the concentration of said analyte in said biological fluid with the assistance of said tetrazolium salt as the indicator.
13. The method of claim 12, wherein said analyte is glucose.
14. The method of claim 13, wherein said biological fluid is whole blood.
15. The method of claim 13, wherein said tetrazolium salt has the formula
wherein:
A=counter-ion
X=1-6C alkyl
a=1-3
b=0-3
R1=1-3C alkyl
one of R2 and R3 is 1-4C alkyl and the other is XN+Hb(R1)3-b, or R2 and R3 form a methylene dioxy group
R4\u2550CHF2
R5\u2550Halogen.
16. The method of claim 15, wherein
X is propyl
b is zero
R1 is methyl
R2 and R3 form a methylene dioxy group R4 is CHF2
R5 is Cl.
17. The method of claim 15, wherein
X is propyl
b is 1
R1 is methyl
R2 and R3 form a methylene dioxy group
R4 is CHF2
R5 is Cl.
18. The method of claim 15, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methoxy
R4 is CHF2
R5 is Cl.
19. The method of claim 12 having the formula wherein:
a=1-3
A=counter-ion
X=1-6C alkyl
b=0-3
R1=1-3C alkyl
one of R2 and R3 is alkyl and the other is XN+Hb(R1)3-b, or R2 and R3 form a methylene dioxy group
one of R4 and R5 is halogen and the other is a halogen substituted 1-6C alkyl, or R4 and R5 are hydrogen
R6=1-4C alkoxy, hydrogen, or halogen.
20. The method of claim 19, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methoxy
R4, R5, and R6 are hydrogen.
21. The method of claim 19, wherein
X is propyl
R1 is methyl
b is zero
R2 is trimethylammonium propyl
R3 is methyl
R4 and R5 form an aromatic ring
R6 is methoxy.
22. The method of claim 19, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methyl
R4 and R5 are hydrogen
R6 is ethoxy.
23. The method of claim 19, wherein
X is propyl
b is zero
R1 is methyl
R2 is trimethylammonium propyl
R3 is methyl
R4 and R5 are hydrogen
R6 is bromine.
24. The method of claim 12, wherein said at least one counter-ion is nitrite, phosphate, hydrogenphosphate, dihydrogen phosphate, hydrogen sulfate, sulfate, hydrogen carbonate, carbonate, methane sulfonate, fluoroborate, bromide, chloride, iodide, or combinations thereof.
25. A method of increasing the solubility of thiazoyl tetrazolium salts having the thiazoyl group attached at the third nitrogen atom of the tetrazolium ring, the method comprising adding at least one trialkyl ammonium alkoxy group as a substituent to the thiazoyl tetrazolium salt.
26. The method of claim 25, wherein said thiazoyl tetrazolium salt has phenyl substituents at the third nitrogen atom and at the carbon atom of the tetrazolium ring.
27. The method of claim 26, wherein said at least one trialkyl ammonium alkoxy group is a trimethyl ammonium propoxy group.
28. The method of claim 26, wherein said at least one trialkyl ammonium alkoxy group is a substituent of said phenyl groups.
29. The method of claim 26, wherein at least one trialkyl ammonium alkoxy group is a substituent of both of said phenyl substituents.
30. The method of claim 25, wherein said thiazoyl group is a benzo thiazoyl group.
31. The method of claim 25, wherein said thiazoyl tetrazolium salt has counterions of nitrite, phosphate, hydrogen phosphate, dihydrogen phosphate, hydrogen sulfate, sulfate, hydrogen carbonate, carbonate, methane sulfonate, fluoroborate, bromode, chloride, iodide, or combinations thereof.
32. The method of claim 31, wherein said counterions are bromo nitrite, dibromo nitrite, or tribromide.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A personal armband storage device comprising:
a body portion having an opening for access to a storage compartment contained within the body portion;
a back plate attached to the body portion, the back plate including a plurality of layers of material arranged to mirror the musculature of a human upper arm in the region where the deltoid muscle, the triceps, muscle, and the bicep muscle meet; and
a strap attached to the back plate for securing the body portion to a user.
2. The personal armband storage device of claim 1, wherein the back plate includes a first region, a second region, and a third region, the second region being thicker than the first region, and the third region being thicker than the first region and the third region being thicker than the second region.
3. The personal armband storage device of claim 2, wherein the back plate further comprises, a first layer of material that extends across the first region, the second region, and the third region; a second layer of material the extends across the second region and the third region, and a third layer of material that extends across the third region.
4. The personal armband storage device of claim 3, wherein the third region is pie-shaped.
5. The personal armband storage device of claim 4, wherein the third region is wider near a top of the body portion and narrower near a bottom of the body portion.
6. The personal armband storage device of claim 1, wherein the back plate includes a plurality of channels adapted to direct moisture away from the back plate.
7. The personal armband storage device of claim 1, wherein the plurality of layers of material are covered by a layer of moisture wicking fabric.
8. The personal armband storage device of claim 1, wherein the strap has a V-shape, including separated end portions that are attached to the back plate.
9. The personal armband storage device of claim 1, wherein the back plate is wider than the body portion.
10. A personal armband storage device comprising:
a body portion having an opening for access to a storage compartment contained within the body portion;
a back plate attached to the body portion; and
a V-shaped strap attached to the back plate for securing the body portion to a user.
11. The personal armband storage device of claim 10, wherein the V-shaped strap includes two separated portions at one end, the two separated portions being attached to the body portion at one side, one separated portion being attached to the body portion proximate a top of the body portion and the other separated portion being attached to the body portion proximate a bottom of the body portion.
12. The personal armband storage device of claim 10, wherein the V-shaped strap includes a plurality of perforations.
13. The personal armband storage device of claim 12, wherein the V-shaped strap is lined with a moisture-wicking material.
14. The personal armband storage device of claim 10, further comprising a soft material flap extending from the back plate, the soft material flap being located between the V-shaped strap and a user’s arm when the personal armband storage device is attached to a user’s arm.
15. The personal armband storage device of claim 10, wherein the back plate includes a first region, a second region, and a third region, the second region being thicker than the first region, and the third region being thicker than the second region, the third region having a pie-shape with a wider portion near a top of the body portion and a narrower portion near a bottom of the body portion.
16. A personal armband storage device comprising:
a body portion having an opening for access to a storage compartment contained within the body portion;
a back plate attached to the body portion, the back plate being adapted to support the body portion on the upper arm of a user; and
a strap attached to the back plate for securing the body portion to a user,
wherein the body portion includes a first window along a first side of the body portion and a first illumination unit disposed within the storage compartment, the first illumination unit being adapted to project a first fan-shaped beam of electromagnetic radiation through the window.
17. The personal armband storage device of claim 16, wherein the body portion includes a second illumination unit disposed within the storage compartment, the second illumination unit being adapted to project a second fan-shaped beam of electromagnetic radiation through the window.
18. The personal armband storage device of claim 17, wherein the first fan-shaped beam and the second fan-shaped beam are symmetrical about a first projection axis and a second projection axis, respectively, the first projection axis being angled relative to the second projection axis.
19. The personal armband storage device of claim 16, wherein the body portion includes a second window along a second side of the body portion, and a second illumination unit disposed within the storage compartment, the second illumination unit being adapted to project a second fan-shaped beam of electromagnetic radiation through the second window.
20. The personal armband storage device of claim 16, wherein the window is tinted to absorb at least one frequency of electromagnetic radiation.