1. A fluorescence detection system comprising:
a substrate disk being rotatable and having a specimen-holding area on which one or more biological specimens are fixed, wherein the one or more biological specimens are fluorescence labeled;
a rotation unit which rotates the substrate disk;
an excitation-light irradiation unit which performs irradiation of each of said one or more biological specimens with excitation light;
a fluorescence-detection unit which detects fluorescence emitted from said each of the one or more biological specimens; and
a control unit which controls said rotation unit, said excitation-light irradiation unit, and said fluorescence-detection unit so that said each of the one or more biological specimens is irradiate with excitation light while the substrate disk is rotated by the rotation unit, and the fluorescence-detection unit detects said fluorescence emitted from said each of the one or more biological specimens when a predetermined time elapses since each of the one or more biological specimens is irradiated with the excitation light,
wherein the substrate disk is arranged in such a manner that the center of the substrate disk is positioned at the center of rotation of the rotation unit,
and wherein the excitation-light irradiation unit is arranged on the upper side of the substrate disk and irradiates a predetermined excitation-light irradiation position on the substrate disk with the excitation light from the upper side of the substrate disk,
and wherein the fluorescence-detection unit is arranged on the upper side of the substrate disk and detects the fluorescence in such a manner that a fluorescence detection position on the substrate disk and the predetermined excitation-light irradiation position are at identical distances from the center of rotation of the rotation unit and at angular positions that are different by angle \u03b8 with respect to the direction of rotation of the rotation unit, wherein \u03b8 is not equal to 0;
and wherein the angle \u03b8 changes based on the speed of rotation of the substrate disk by the rotation unit.
2. A fluorescence detection system according to claim 1, wherein said one or more biological specimens are labeled with a fluorescent material having a fluorescent lifetime on the order of microseconds to milliseconds.
3. A fluorescence detection system according to claim 1, wherein said specimen-holding area is realized by one or more grooves spirally or concentrically arranged on the substrate disk.
4. A fluorescence detection system according to claim 3, wherein each of said one or more grooves has a width which is greater than a diameter of a light spot which said excitation light forms on said substrate disk.
5. A fluorescence detection system according to claim 1, wherein said substrate disk is opaque to said excitation light.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A granular pesticide composition enabling dissolution control for each pesticidal active ingredient, having a granule size of 0.3 to 3 mm in diameter or of 0.6 to 3 mm in breadth and 2 to 10 mm in length, which comprises a non-disintegrable part in the form of granules being not disintegrated in water within 30 minutes and a disintegrable part being disintegrated in water within 30 minutes,
wherein the non-disintegrable part contains (a) first acidic pesticidal active ingredient selected from sulfonylurea-based compounds and difluoromethanesulfonylanilide compounds represented by the formula,
wherein R1 is a hydrogen atom, alkyl group or alkoxyalkyl group, and salts thereof, (b) a cationic surfactant which is gelled in water selected from dialkyldimethylammonium chlorides wherein the alkyl part has 8-22 carbon atoms, and (c) a basic substance having a pH of 7.5 or higher in a 1 wt % aqueous solution or a 1 wt % aqueous suspension, and
wherein the disintegrable part contains a second pesticidal active ingredient selected from compounds other than the first acidic pesticidal active ingredient (a).
2. The granular pesticide composition according to claim 1, wherein the basic substance is sodium hydrogen carbonate, sodium carbonate, calcium hydroxide, calcium carbonate, basic white carbon or basic Japanese acid clay.
3. The granular pesticide composition according to claim 1, wherein the cationic surfactant is dilaurydimethylammonium chloride, dioleyldimethylammonium chloride, dicocoyldimethylammonium chloride or distearyldimethylammonium chloride.
4. A process of preparing a granular pesticide composition enabling dissolution control for each pesticidal active ingredient according to claim 1, which process comprises the step of subjecting granules as the non-disintegrable part containing a first pesticidal active ingredient, a cationic surfactant and a basic substance, a second a pesticidal active ingredient, a nonionic or anionic surfactant and an extender to an extrusion granulation through a screen of which the mesh opening has a diameter larger than the granule size or granule length of the non-disintegrable part to form granules of the granular pesticidal composition enabling dissolution control for each pesticidal active ingredient having a granule size of 0.3 to 3 mm in diameter or of 0.6 to 3 mm in breadth and 2 to 10 mm in length, wherein the first acidic pesticidal active ingredient is selected from sulfonylurea-based compounds and difluoromethanesulfonylanilide derivatives represented by the formula,
wherein R1 is a hydrogen atom, alkyl group or alkoxyalkyl group, and salts thereof wherein the cationic surfactant which is gelled in water is selected from dialkyldimethylammonium chlorides wherein the alkyl part has 8-22 carbon atoms, wherein the basic substance has a pH of 7.5 or higher in a 1 wt. % aqueous solution or a 1 wt. % aqueous suspension, and
wherein the second pesticidal active ingredient is selected from compounds other than the first acidic pesticidal active ingredient.