1461130327-dad3c0fb-1520-43a9-86d7-3583a818b480

1. An in-line valve device comprising:
a housing that includes a proximal portion, a distal portion and a chamber therein extending between the proximal and distal portions, the proximal portion including a proximal opening that is fluidly coupled to the chamber;
a tubular member that is coupled to the housing distal portion such that a lumen thereof is fluidly coupled to the chamber;
a seal member that is disposed within the chamber to seal the proximal opening from the chamber, the proximal opening being selectively fluidly coupled to the chamber by moving a sealing portion of the seal member out of engagement with the proximal portion of the housing; and
a securing member positioned to secure a distal end of the seal member to the housing proximal portion such that the seal member is compressibly retained between a proximal end of the chamber and the securing member.
2. The in-line device of claim 1, wherein the securing member is an annular ring.
3. The in-line device of claim 2, further including a groove formed in the housing proximal portion dimensioned to receive and axially retain the annular ring.
4. The in-line device of claim 1, wherein the securing member includes a raised rib formed about an inner circumference of the proximal portion of the housing.
5. The in-line device of claim 1, wherein:
the seal member includes one or more through apertures extending between an inner cavity and an outside surface of the seal member; and
the seal member is arranged in the housing proximal portion so that the seal member inner cavity is fluidly coupled to a portion of the chamber disposed in the housing distal portion.
6. The in-line device of claim 1, wherein the seal member includes a septum in which an introducer needle is removably received.
7. The in-line device of claim 6, wherein:
the seal member includes a proximal end;
a portion of the seal member proximal end includes a sealing portion for sealing engagement with at least a portion of the chamber proximal end; and
the seal member septum is arranged so the septum lies in the same general axial plane as the sealing portion.
8. The in-line device of claim 6, wherein:
the seal member includes a proximal end; and
the seal member is configured so that the septum is spaced distally from the sealing portion.
9. The in-line device of claim 1, wherein the housing distal portion includes at least one axially extending fin extending from an inner surface of a portion of the inner chamber disposed within the housing distal portion.
10. The in-line device of claim 9, wherein the at least one axially extending fin is arranged so as to only contact the seal member during a high pressure fluid flow condition.
11. A vascular access device comprising:
a housing that includes a proximal portion, a distal portion and a chamber therein extending between the proximal and distal portions, the proximal portion including a proximal opening that is fluidly coupled to the chamber;
a tubular member that is coupled to the housing distal portion such that a lumen thereof is fluidly coupled to the chamber;
a seal member that is disposed within the chamber to seal the proximal opening from the chamber, the proximal opening being selectively fluidly coupled to the chamber by moving a sealing portion of the seal member out of engagement with the proximal portion of the housing; and
wherein the housing distal portion includes at least one axially extending fin extending from an inner surface of a portion of the inner chamber disposed within the housing distal portion.
12. The vascular access device of claim 11, wherein the at least one axially extending fin is arranged so as to only contact the seal member during a high pressure fluid flow condition.
13. A method for assembling an in-line IV catheter device comprising the steps of:
providing a proximal housing portion defining an internal cavity, the proximal housing portion having a proximal end and a distal end;
providing a distal housing portion defining an internal cavity, the distal housing portion having a proximal end and a distal end;
providing a seal member having a proximal end, a distal end, and including a septum;
positioning the seal member in the internal cavity of the proximal housing portion;
providing a needle having a sharpened distal end and a proximal end;
inserting the proximal end of the needle through the septum of the seal member such that the proximal end of the needle projects from the proximal end of the seal member; and
securing the proximal housing portion to the distal housing portion such that the internal cavities of the proximal and distal housing portions define a chamber.
14. The method of claim 13, wherein the step of positioning the seal member in the internal cavity of the proximal housing portion further includes the step of securing the seal member distal end to the proximal housing portion such that the seal member is sealingly and compressibly retained against the proximal end of the proximal housing portion inner cavity.
15. The method of claim 14, wherein the step of securing includes:
positioning a ring member on the proximal housing portion a predetermined distance from the proximal end of the proximal housing portion inner cavity; and
compressibly retaining the seal member between the proximal end of the proximal housing portion inner cavity and a surface of the ring member.
16. The method of claim 15, wherein the ring member is an annular plate like member.
17. The method of claim 16, wherein the step of positioning the ring member includes positioning the ring member in a groove formed in the proximal housing portion.
18. The method of claim 15, wherein the ring member is formed as a raised rib which extends at least partially about the circumference of the internal cavity of the proximal housing portion.
19. The method of claim 13, wherein the step of providing a seal member includes forming a resealable opening through the septum, and
the step of inserting the proximal end of the needle through the septum includes inserting the proximal end of the needle through the resealable opening.
20. The method of claim 13, wherein the seal member includes an inner cavity and at least one through aperture extending between the inner cavity and an outside surface of the seal member.
21. The method of claim 20, wherein the step of positioning the seal member includes the step of disposing the seal member in the proximal housing portion internal cavity such that the at least one through aperture is proximal the proximal end of the proximal housing portion inner cavity and such that the seal member inner cavity is fluidly coupled to the distal housing portion internal cavity after the proximal and distal housing portions are secured to each other.
22. The method of claim 13, further including the step of providing one or more radially extending fins within the distal housing portion, the one or more radially extending fins being positioned to limit axial travel of the seal member when the seal member is exposed to a high pressure fluid flow condition.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. In a photocatalytically active polysiloxane composition for coating a substrate comprising:
(a) from 0.5% to 20% by weight, based on the total weight of the composition, of photocatalytic titanium dioxide particles having a mean particle size between 2 nm and 100 nm;
(b) from 0.05% to 40% by weight of calcium carbonate particles, wherein the ratio of calcium carbonate particles to photocatalytic titanium dioxide particles is from 0.01 to 50; and
(c) a solvent selected from water, an organic solvent or a mixed solvent consisting of water and an organic solvent, the improvement comprising incorporating into said polysiloxane composition from 0.1% to 20% by weight (expressed in dry matter), based on the total weight of the composition, of hollow styrene resin microspheres having an outside diameter of from 0.1 \u03bcm to 10 \u03bcm whereby
(i) the opacity of a dry film coating formed from said polysiloxane composition is greater than the opacity of a dry film coating formed from the same polysiloxane composition that does not include said hollow styrene resin microspheres, and
(ii) percent weight loss of said dry film coating over a defined time period is less than percent weight loss of the same polysiloxane dry film coating over the same defined time period, but without having said hollow styrene resin microspheres present in the polysiloxane composition.
2. The coating composition of claim 1 wherein the styrene resin hollow microspheres are selected from the group consisting of polystyrene, poly-a-methylstyrene, and styrene-acrylic copolymer resins.
3. The coating composition of claim 2 wherein the styrene resin hollow microspheres are selected from styrene-acrylic copolymer resins.