What is claimed is:
1. A compound 8 to 80 nucleobases in length targeted to a nucleic acid molecule encoding BRCA2 region transcription unit CG005, wherein said compound specifically hybridizes with said nucleic acid molecule encoding BRCA2 region transcription unit CG005 (SEQ ID NO: 4) and inhibits the expression of BRCA2 region transcription unit CG005.
2. The compound of claim 1 comprising 12 to 50 nucleobases in length.
3. The compound of claim 2 comprising 15 to 30 nucleobases in length.
4. The compound of claim 1 comprising an oligonucleotide.
5. The compound of claim 4 comprising an antisense oligonucleotide.
6. The compound of claim 4 comprising a DNA oligonucleotide.
7. The compound of claim 4 comprising an RNA oligonucleotide.
8. The compound of claim 4 comprising a chimeric oligonucleotide.
9. The compound of claim 4 wherein at least a portion of said compound hybridizes with RNA to form an oligonucleotide-RNA duplex.
10. The compound of claim 1 having at least 70% complementarity with a nucleic acid molecule encoding BRCA2 region transcription unit CG005 (SEQ ID NO: 4) said compound specifically hybridizing to and inhibiting the expression of BRCA2 region transcription unit CG005.
11. The compound of claim 1 having at least 80% complementarity with a nucleic acid molecule encoding BRCA2 region transcription unit CG005 (SEQ ID NO: 4) said compound specifically hybridizing to and inhibiting the expression of BRCA2 region transcription unit CG005.
12. The compound of claim 1 having at least 90% complementarity with a nucleic acid molecule encoding BRCA2 region transcription unit CG005 (SEQ ID NO: 4) said compound specifically hybridizing to and inhibiting the expression of BRCA2 region transcription unit CG005.
13. The compound of claim 1 having at least 95% complementarity with a nucleic acid molecule encoding BRCA2 region transcription unit CG005 (SEQ ID NO: 4) said compound specifically hybridizing to and inhibiting the expression of BRCA2 region transcription unit CG005.
14. The compound of claim 1 having at least one modified internucleoside linkage, sugar moiety, or nucleobase.
15. The compound of claim 1 having at least one 2-O-methoxyethyl sugar moiety.
16. The compound of claim 1 having at least one phosphorothioate internucleoside linkage.
17. The compound of claim 1 having at least one 5-methylcytosine.
18. A method of inhibiting the expression of BRCA2 region transcription unit CG005 in cells or tissues comprising contacting said cells or tissues with the compound of claim 1 so that expression of BRCA2 region transcription unit CG005 is inhibited.
19. A method of screening for a modulator of BRCA2 region transcription unit CG005, the method comprising the steps of:
a. contacting a preferred target segment of a nucleic acid molecule encoding BRCA2 region transcription unit CG005 with one or more candidate modulators of BRCA2 region transcription unit CG005, and
b. identifying one or more modulators of BRCA2 region transcription unit CG005 expression which modulate the expression of BRCA2 region transcription unit CG005.
20. The method of claim 21 wherein the modulator of BRCA2 region transcription unit CG005 expression comprises an oligonucleotide, an antisense oligonucleotide, a DNA oligonucleotide, an RNA oligonucleotide, an RNA oligonucleotide having at least a portion of said RNA oligonucleotide capable of hybridizing with RNA to form an oligonucleotide-RNA duplex, or a chimeric oligonucleotide.
21. A diagnostic method for identifying a disease state comprising identifying the presence of BRCA2 region transcription unit CG005 in a sample using at least one of the primers comprising SEQ ID NOs 5 or 6, or the probe comprising SEQ ID NO: 7.
22. A kit or assay device comprising the compound of claim 1.
23. A method of treating an animal having a disease or condition associated with BRCA2 region transcription unit CG005 comprising administering to said animal a therapeutically or prophylactically effective amount of the compound of claim 1 so that expression of BRCA2 region transcription unit CG005 is inhibited.
24. The method of claim 16 wherein the disease or condition is a hyperproliferative disorder.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A digital camera which can communicate with a printer, composing:
a display unit adapted to display a printing condition;
a discrimination unit adapted to discriminate printable sizes by a printer; and
a display control unit adapted to cause said display unit to display a list of sizes in accordance with the printable sizes discriminated by said discrimination unit so that a user selects one of sizes,
wherein said display control unit cause said display unit to display an additional option, as a member of the list, for automatically resizing the size of an image to be printed so as to correspond to a size of a print medium actually set in the printer, based on the discriminated printable sizes and the size of the print medium actually set in the printer.
2. The digital camera according to claim 1, wherein a magnification ratio for resizing the image has a limiter.
3. The digital camera according to claim 2, wherein the limiter is determined in accordance with printing resolution of the printer.
4. The digital camera according to claim 1, further comprising a selection unit adapted to select one of options in the list displayed by said display unit.
5. A method for controlling a digital camera which can directly communicate with a printer using a communication unit, comprising:
a display step of displaying a printing condition;
a discrimination step of discriminating printable sizes by a printer; and
a display control step of controlling said display step to display a list of sizes in accordance with the printable sizes discriminated in said discrimination step so that a user selects one of the printable sizes,
wherein said display step displays an additional option, as a member of the list, for automatically resizing the size of an image to be printed so as to correspond to a size of a print medium actually set in the printer, based on the discriminated printable sizes and the size of the print medium actually set in the printer.
6. The method according to claim 5, wherein a magnification ratio for resizing the image has a limit.
7. The method according to claim 6, wherein the limit is determined in accordance with printing resolution of the printer.
8. The method according to claim 5, further comprising a selection step of selecting one of options in the list displayed in said display step.
9. A computer-readable medium storing a computer program for controlling a digital camera which can communicate with a printer, comprising:
a display step of displaying a printing condition;
a discrimination step of discriminating printable sizes by a printer; and
a display control step of causing said display step to display a list of sizes in accordance with the printable sizes discriminated in said discrimination step so that a user selects one of the printable sizes,
wherein said display step displays an additional option, as a member of the list, for automatically resizing the size of an image to be printed so as to correspond to a size of a print medium actually set in the printer, based on the discriminated printable sizes and the size of the print medium actually set in the printer.
10. A computer program stored on a computer-readable medium, the computer program controlling a digital camera which can communicate with a printer, comprising:
a display step of displaying a printing condition;
a discrimination step of discriminating printable sizes by a printer; and
a display control step of causing said display step to display a list of sizes in accordance with the printable sizes discriminated in said discrimination step so that a user selects one of the printable sizes,
wherein said display step displays an additional option, as a member of the list, for automatically resizing the size of an image to be printed so as to correspond to a size of a print medium actually set in the printer, based on the discriminated printable sizes and the size of the print medium actually set in the printer.