1. A method of generating location data for a mobile device, comprising:
initiating a voice call from a calling device to a called mobile device;
receiving a request from the calling device to capture location data of the called mobile device;
initiating a paging process to locate the called mobile device via a called device service provider;
identifying a cell sector location for the called mobile device based on a paging response of the called mobile device via the called device service provider;
generating called device location data for the called mobile device based on the cell sector location identified via the called device service provider;
transmitting the called device location data to the calling device; and
storing information related to the voice call between the calling device and the called mobile device, wherein the storing information includes storing at least one geographic location of the called device.
2. The method of claim 1, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
3. The method of claim 1, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
4. The method of claim 1, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
5. The method of claim 1, wherein the transmitting the called device location data to the calling device comprises at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
6. The method of claim 1, further comprising generating an update to the called device location data based on a change in position of the called mobile device.
7. A system for generating location data for a mobile device, comprising:
a server, communicating with a wireless interface to a called mobile device, the server being configured to:
initiate a voice call from a calling device to the called mobile device,
receive a request from the calling device to capture location data of the called mobile device,
initiate a paging process to locate the called mobile device via a called device service provider,
identify a cell sector location for the called mobile device based on a paging response of the called mobile device via the called device service provider,
generate called device location data for the called mobile device based on the cell sector location identified via the called device service provider,
transmit the called device location data to the calling device; and
store information related to the voice call between the calling device and the called mobile device, wherein the server configured to store information includes storing at least one geographic location of the called device.
8. The system of claim 7, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
9. The system of claim 7, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
10. The system of claim 7, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
11. The system of claim 7, wherein the called device location data is transmitted to the calling device via at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
12. The system of claim 7, wherein the server is further configured to generate an update to the called device location data based on a change in position of the called mobile device.
13. A system for generating location data for a mobile device, comprising:
means for serving data to a called mobile device, the means for serving data being configured to:
initiate a voice call from a means for calling to the called mobile device,
receive a request from the means for calling to capture location data of the called mobile device,
initiate a paging process to locate the called mobile device via a called device service provider,
identify a cell sector location for the called mobile device based on a paging response of the called mobile device via the called device service provider,
generate called device location data for the called mobile device based on the cell sector location identified via the called device service provider,
transmit the called device location data to the means for calling; and
store information related to the voice call between the means for calling and the called mobile device, wherein the means configured to store information further includes storing at least one geographic location of the called device.
14. The system of claim 13, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
15. The system of claim 13, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
16. The system of claim 13, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
17. The system of claim 13, wherein the called device location data is transmitted to the calling device via at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
18. The system of claim 13, wherein the means for serving is further configured to generate an update to the called device location data based on a change in position of the called mobile device.
19. A non-transitory computer-readable medium comprising:
at least one instruction for causing a computer to initiate a voice call from a calling device to a called mobile device;
at least one instruction for causing the computer to receive a request from the calling device to capture location data of the called mobile device;
at least one instruction for causing the computer to initiate a paging process to locate the called mobile device via a called device service provider;
at least one instruction for causing the computer to identify a cell sector location for the called mobile device based on a paging response of the called mobile device via the called device service provider;
at least one instruction for causing the computer to generate called device location data for the called mobile device based on the cell sector location identified via the called device service provider;
at least one instruction for causing the computer to transmit the called device location data to the calling device; and
at least one instruction for causing the computer to store information related to the voice call between the calling device and the called mobile device, wherein the at least one instruction to store information includes storing at least one geographic location of the called device.
20. The non-transitory computer-readable medium of claim 19, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
21. The non-transitory computer-readable medium of claim 19, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
22. The non-transitory computer-readable medium product of claim 19, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
23. The non-transitory computer-readable of claim 19, wherein the transmitting the called device location data to the calling device comprises at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
24. The non-transitory computer-readable medium of claim 19, further comprising generating an update to the called device location data based on a change in position of the called mobile device.
25. A method of receiving location information for a called device, comprising;
initiating a voice call to a called mobile device serviced by a called device service provider;
generating a request to capture location data of the called mobile device;
initiating a paging process to locate the called mobile device via the called device service provider;
receiving called device location data for the called mobile device based on a cell sector location identified via the paging process of the called device service provider; and
storing the received called device location data for the called mobile device.
26. The method of claim 25, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
27. The method of claim 25, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
28. The method of claim 25, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
29. The method of claim 25, wherein the called device location data is received in the communications device via at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
30. The method of claim 25, further comprising receiving an update to the called device location data based on a change in position of the called mobile device.
31. A communications device, comprising:
an interface to a called device service provider; and
a processor, communicating with the interface, the processor being configured to:
initiate a voice call to a called mobile device serviced by the called device service provider,
generate a request to capture location data of the called mobile device,
initiate a paging process to locate the called mobile device via the called device service provider,
receive called device location data for the called mobile device based on a cell sector location identified via the paging process of the called device service provider; and
store the received called device location data for the called mobile device.
32. The device of claim 31, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
33. The device of claim 31, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
34. The device of claim 31, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
35. The device of claim 31, wherein the called device location data is received in the communications device via at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
36. The device of claim 31, wherein the processor is further configured to receive an update to the called device location data based on a change in position of the called mobile device.
37. A communications device, comprising:
means to provide an interface to a called device service provider; and
means for processing, communicating with the interface, the means for processing being configured to:
initiate a voice call to a called mobile device serviced by the called device service provider,
generate a request to capture location data of the called mobile device,
initiate a paging process to locate the called mobile device via the called device service provider,
receive called device location data for the called mobile device based on a cell sector location identified via the paging process of the called device service provider; and
store the received called device location data for the called mobile device.
38. The device of claim 37, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
39. The device of claim 37, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
40. The device of claim 37, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
41. The device of claim 37, wherein the called device location data is received in the communications device via at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
42. The device of claim 37, wherein the means for processing is further configured to receive an update to the called device location data based on a change in position of the called mobile device.
43. A non-transitory computer-readable medium, the non-transitory computer-readable medium being configured to program a communications device, comprising:
at least one instruction for causing a computer to initiate a voice call to a called mobile device serviced by a called device service provider;
at least one instruction for causing the computer to generate a request to capture location data of the called mobile device;
at least one instruction for causing the computer to initiate a paging process to locate the called mobile device via the called device service provider;
at least one instruction for causing the computer to receive called device location data for the called mobile device based on a cell sector location identified via the paging process of the called device service provider; and
at least one instruction for causing the computer to store the received called device location data for the called mobile device.
44. The non-transitory computer-readable medium of claim 43, wherein the called mobile device comprises at least one of a cellular telephone, a Global Positioning System (GPS) device, a network-enabled personal digital assistant device, or a network-enabled media player device.
45. The non-transitory computer-readable medium of claim 43, wherein the request to capture location data of the called mobile device comprises at least one of automatically initiating the request based on a user profile or initiating the request based on a user-supplied input.
46. The non-transitory computer-readable medium of claim 43, wherein the called device location comprises at least a set of longitude and latitude readings based on the cell sector location.
47. The non-transitory computer-readable medium of claim 43, wherein the called device location data is received in the communications device via at least one of transmitting the called device location data via a SMS (short message service) message, or transmitting the called device location data via a GSM (Global System for Mobile communication) Unstructured Supplementary Service Data (USSD) message.
48. The non-transitory computer-readable medium of claim 43, further comprising at least one instruction for causing the computer to receive an update to the called device location data based on a change in position of the called mobile device.
49. The method of claim 1, wherein the storing information related to the voice call between the calling device and the called mobile device comprises one at least one of storing the information on the calling device or the called device.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
What is claimed is:
1. A compound having the Formula I, and pharmaceutically acceptable salts thereof,
319
wherein:
W is O or S;
R1 is (CRR)nX;
X is H, C1-12 alkyl, C2-12 alkenyl, C2-12 alkynyl, C3-7 cycloalkyl, C4-7 cycloalkenyl, each of said alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl being optionally substituted with one to six of the same or different halogen atoms; halogen, CN, OR, OCOR, NRR, NRCOR, NRCONRR, NRSO2R, NRCOOR, COR, CRNNRR, CRNOR, COOR, CONRR, SOmR, PO(OR)2, aryl, heteroaryl or non-aromatic heterocycle;
m is 0-2; n is 2-6;
R2 is
(i) H, C1-12 alkyl, C2-12 alkenyl, C2-12 alkynyl, C3-7 cycloalkyl, C4-7 cycloalkenyl, (CH2)t C3 7 cycloalkyl, (CH2)t C4-7 cycloalkenyl, each of said alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl being optionally substituted with one to six of the same or different halogen atoms; SO2R, SO2NRR or CN; wherein t is 1-6;
(ii) (CRR)nY, wherein Y is CN, OR, OCONRR, NRR, NCOR, NRSO2R, NRCOOR, NRCONRR, COR, CRNNRR, CRNOR, COOR, CONRR, SOmR, SO2NRR or PO(OR)2; wherein
m is 0-2 and n is 1-6;
(iii) (CRR)n-C6H4Z, wherein the Z group may be in the ortho, meta or para position relative to the (CH2)n group; Z is CN, OR, OCONRR, NO2, NRR, NCOR, NRSO2R, NRCOOR, NRCONRR, COR, CRNNRR, CRNOR, COOR, CONRR, SOmR, SO2NRR or PO(OR)2;
m is 0-2; n is 0-6; or
(iv) (CRR)n-heteroaryl, wherein n is 0-6;
(v) (CRR)n-non-aromatic heterocycle, wherein n is 0-6;
R3, R4, R5 and R6 are each independently hydrogen, halogen, C1-6 alkyl, C1-6 alkyl substituted with one to six of the same or different halogen atoms, OR, CN, COR, COOR, CONRR, or NO2;
A, B, E, D are each independently CH, CQ, N, or NO; provided at least one of A, B, E or D is not CH or CQ; wherein Q is halogen, C1-3 alkyl or C1-3 alkyl substituted with one to three of the same or different halogen atoms; and
R, R, R are each independently H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-7 cycloalkyl, C4-7 cycloalkenyl, each of said alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl being optionally substituted with one to six of the same or different halogen atoms; or R and R taken together form a cyclic alkyl group having 3 to 7 carbon atoms; benzyl, or aryl;
R is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-7 cycloalkyl, C4-7 cycloalkenyl, NRR, CRNRR, aryl, heteroaryl, non-aromatic heterocycle; and
Non-aromatic heterocycle is a 3-7 membered non-aromatic ring containing at least one and up to 4 non-carbon atoms selected from the group consisting of O, S, N, and NR;
Aryl is phenyl, naphthyl, indenyl, azulenyl, fluorenyl and anthracenyl;
Heteroaryl is a 4-7 membered aromatic ring which contains one to five heteroatoms independently selected from the group consisting of O, S, N or NR, wherein said aromatic ring is optionally fused to group B;
B is an aromatic group selected from the group consisting of phenyl, 1-naphthyl, 2-naphthyl, indenyl, azulenyl, fluorenyl, and anthracenyl;
Aryl, B, said 4-7 membered aromatic ring, and said 3-7 membered non-aromatic ring may each independently contain one to five substituents which are each independently selected from R7, R8, R9, R10 or R11; and
R7, R8, R9, R10 and R11 are each independently
(i) H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-7 cycloalkyl, C4-7 cycloalkenyl, each of said alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl being optionally substituted with one to six of the same or different halogen atoms; and
(ii) halogen, CN, NO2, OR, NRR, COR, COOR, CONRR, OCOR, NRCOR, SOmR, SO2NRR, PO(OR)2.
2. The compound of claim 1 wherein heteroaryl is selected from the group consisting of 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyridyl, 3-pyridyl, 4-pyridyl, pyrrolyl, oxazolyl, thiazolyl, imidazolyl, pyrazolyl, isoxazolyl, isothiazolyl, 1,2,3-oxadiazolyl, 1,2,4-oxadiazolyl, 1,2,4-oxadiazol-5-one, 1,2,3-triazolyl, 1,3,4-thiadiazolyl, pyridazinyl, pyrimidinyl, pyrazinyl, 1,3,5-triazinyl, 1,3,5-trithianyl, indolizinyl, indolyl, isoindolyl, 3H-indolyl, indolinyl, benzoylfuranyl, benzobthiophenyl, 1H-indazolyl, benzimidazolyl, benzthiazolyl, purinyl, 4H-quinolizinyl, quinolinyl, isoquinolinyl, cinnolinyl, phthalazinyl, quinazolinyl, quinoxalinyl, 1,8-naphthyridinyl, pteridinyl, carbazolyl, acridinyl, phenazinyl, phenothiazinyl, tetrazole and phenoxazinyl.
3. A compound of claim 2 wherein:
R1 is (CH2)nX;
X is H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, C3-6 cycloalkenyl, each of said alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl being optionally substituted with one to six of the same or different halogen atoms; halogen, CN, OR, OCOR, NRR, NRCOR, NRCOOR, COR, CRNNRRR, CRNOR, COOR, CONRR, SOmR, aryl or heteroaryl;
m is 0-2; n is 2-4;
R2 is
(i) H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, C3-6 cycloalkenyl, (CH2)t C3-7 cycloalkyl, (CH2)t C4-7 cycloalkenyl, each of said alkyl, alkenyl, alkynyl, cycloalkyl and cycloalkenyl being optionally substituted with one to six of the same or different halogen atoms; SO2R, SO2NRR or CN; wherein t is 1-6;
(ii) (CH2)nY, wherein Y is CN, OR, COR, COOR, CONRR, SOmR, SO2NRR, PO(OR)2 wherein m is 0-2 and n is 1-6; or
(iii) (CH2)nC6H4Z, wherein the Z group may be in the ortho, meta or para position relative to the (CH2)n group; Z is CN, OR, COR or SOmR; m is 0-2; n is 0-3;
R3, R4, R5, and R6 are each independently hydrogen, halogen, C I6 alkyl, optionally substituted with one to six of the same or different halogen atoms; and
A, B, E, D are each independently CH or N; provided at least one of A, B, E or D is not CH.
4. A compound of claim 2 wherein:
R3, R4, R5 and R6 are each H;
A, B and D are each CH; and
E is N.
5. A compound of claim 2 wherein:
R3, R4, R5 and R6 are each H;
A, B and E are each CH; and
D is N.
6. A method for treating mammals infected with RSV, and in need thereof, which comprises administering to said mammal a therapeutically effective amount of a compound having the Formula I, and pharmaceutically acceptable salts thereof, as claimed in any one of claims 1-5.
7. A pharmaceutical composition which comprises a therapeutically effective amount of an anti-RSV compound having Formula I, and pharmaceutically acceptable salts thereof, as claimed in any one of claims 1-5, and a pharmaceutically acceptable carrier.