1. A rapidly disintegrable solid preparation which comprises (i) a pharmacologically active ingredient, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group.
2. A preparation of claim 1, which is an orally rapidly disintegrable solid preparation.
3. A preparation of claim 1 or 2, which is a tablet.
4. A preparation of claim 1, wherein the sugar is a sugar alcohol.
5. A preparation of claim 4, wherein the sugar alcohol is mannitol or erythritol.
6. A preparation of claim 1, wherein the sugar is in an amount of 5 to 97 parts by weight per 100 parts by weight of the solid preparation.
7. A preparation of claim 1, wherein the low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group is used in an amount of 3 to 50 parts by weight per 100 parts by weight of the solid preparation.
8. A preparation of claim 1, wherein the pharmacologically active ingredient is lansoprazole.
9. A preparation of claim 1, wherein the pharmacologically active ingredient is voglibose.
10. A preparation of claim 1, wherein the pharmacologically active ingredient is manidipine hydrochloride.
11. A preparation of claim 1, wherein the pharmacologically active ingredient is pioglitazone hydrochloride.
12. A preparation of claim 1, wherein the pharmacologically active ingredient is candesartan cilexetil.
13. A preparation of claim 3 which comprises fine granules.
14. A preparation of claim 13, wherein the pharmacologically active ingredient is comprised in fine granules of the solid preparation.
15. A preparation of claim 14, wherein (i) a sugar and (ii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group are comprised in the solid preparation separately from fine granules.
16. A preparation of claim 15, wherein the sugar is in an amount of 5 to 97 parts by weight per 100 parts by weight of the rest of the solid preparation other than the fine granules.
17. A preparation of the claim 15, wherein the low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group is in an amount of 3 to 50 parts by weight per 100 parts by weight of the rest of the solid preparation other than the fine granules.
18. Use of a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group for producing a rapidly disintegrable solid preparation comprising a pharmacologically active ingredient and a sugar.
19. A method for improving fast disintegrability of a solid preparation comprising a pharmacologically active ingredient and a sugar which is characterized in that a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group is contained therein.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A secondary battery system comprising:
a) a battery system stack comprising at least one negative electrode, wherein the negative electrode comprises an oxidizable metal;
b) a device for separating materials contained in a fluid stream from the battery system stack, the device having an inlet operably connected to the battery system stack, having a first outlet operably connected to the battery system stack and having a second outlet;
c) an oxygen reservoir having an outlet operably connected to the battery system stack, and having an inlet; and
d) a compressor having an outlet operably connected to the inlet of the oxygen reservoir, and having an inlet operably connected to the second outlet of the device.
2. The secondary battery system of claim 1:
wherein, the device comprises a cold trap.
3. The secondary battery system of claim 1:
wherein, the device comprises an expander.
4. The secondary battery system of claim 1:
wherein, the compressor is a multi-stage compressor comprising a first compression stage, a second compression stage, and a cooling system, and the cooling system is configured to provide a coolant to the multi-stage compressor to cool a compressed fluid between the first compression stage and the second compression stage.
5. The secondary battery system of claim 1:
wherein the oxidizable metal comprises a metal selected from the list consisting of: lithium, aluminum, sodium, calcium, cesium, iron, magnesium, or zinc.
6. A secondary battery system comprising:
a) a battery system stack comprising at least one negative electrode, wherein the negative electrode comprises an oxidizable metal; and
b) an expander having an inlet operably connected to the battery system stack, and having an outlet operably connected to the battery system stack to return captured electrolyte to the battery system stack.
7. The secondary battery system of claim 6:
wherein, the expander further comprises an outlet configured to vent remaining fluid to the atmosphere.
8. The secondary battery system of claim 6:
further comprising, an oxygen reservoir, and a compressor, the compressor comprising an inlet operably connected to the expander, and an outlet operably connected to the oxygen reservoir, wherein, the compressor is a multi-stage compressor comprising a first compression stage, a second compression stage, and a cooling system, and the cooling system is configured to provide a coolant to the multi-stage compressor to cool a compressed fluid between the first compression stage and the second compression stage.
9. The secondary battery system of claim 6:
further comprising, at least one sensor configured to generate a signal associated with a voltage within the secondary battery system;
a memory; and
a processor operably connected to the memory and the at least one sensor, the processor configured to execute program instructions stored within the memory to obtain the signal generated by the at least one sensor, and control a flow of a fluid to the battery system stack based upon the obtained signal.
10. The secondary battery system of claim 6:
further comprising, a pump, the pump configured to assist the flow of captured electrolyte from the expander to the battery system stack.
11. The secondary battery system of claim 6:
further comprising at least one sensor configured to generate a signal associated with a temperature within the secondary battery system.
12. The secondary battery system of claim 6:
further comprising at least one sensor configured to generate a signal associated with a current within the secondary battery system.
13. The secondary battery system of claim 6:
wherein the oxidizable metal comprises a metal selected from the list consisting of: lithium, aluminum, sodium, calcium, cerium, cesium, magnesium, or zinc.
14. A method of operating a secondary battery system comprising:
charging a secondary battery system stack including at least one positive electrode including a form of an oxidized metal;
transferring fluid formed by charging the secondary battery system stack to a cold trap or an expander;
separating, in the cold trap or expander, at least one material from the fluid to obtain a separated material;
obtaining a signal generated by at least one sensor associated with the secondary battery system; and
controlling a flow of the separated material to the secondary battery system stack based upon the obtained signal.
15. The method of claim 14:
wherein, the oxidized metal comprises a form of at least one of lithium, aluminum, sodium, calcium, cerium, cesium, magnesium, or zinc.
16. The method of claim 14:
further comprising, after separating the at least one material, releasing remaining fluid in the cold trap or expander to the atmosphere.
17. The method of claim 14:
further comprising, after separating the at least one material, transferring remaining fluid in the cold trap or expander to a compressor;
compressing the transferred fluid in the compressor; and
transferring compressed fluid from the compressor to a reservoir operably connected to the secondary battery system stack.
18. The method of claim 17:
wherein, the compressor is a multi-stage compressor, and wherein, compressing the transferred fluid further comprises, compressing the transferred fluid in a first compression stage of the multi-stage compressor;
compressing the compressed fluid from the first compression stage in a second compression stage of the multi-stage compressor; and
providing coolant to the multi-stage compressor.
19. The method of claim 14:
wherein, the compressed fluid comprises oxygen.