What is claimed is:
1. A printing order reception method for accepting an order of a printed matter via network comprising the steps of:
storing print content data used in a case of printing a first type of printing medium;
generating print data to be printed on a second type of printing medium by using the stored print content data; and
transmitting the generated print data to an external device.
2. The printing order reception method according to claim 1, further comprising the steps of:
generating a print image to be printed on the second type of printing medium; and
transmitting the generated print image to a network terminal.
3. The printing order reception method according to claim 2, further comprising the steps of storing attribute information of the print content data; and
generating the print image by using at least a part of the attribute information stored.
4. The printing order reception method according to claim 2, further comprising the step of:
copying at least a part of the attribute information as second attribute information.
5. The printing order reception method according to claim 4, further comprising the step of:
generating the print image by using the second attribute information.
6. The printing order reception method according to claim 4, further comprising the steps of:
accepting instruction information instructing correction of the second attribute information from the network terminal; and
correcting the second attribute information in accordance with the accepted instruction information.
7. The printing order reception method according to claim 3, further comprising the step of:
generating the print image by using the attribute information and attribute information stored in advance and used for the generation of the print data.
8. The printing order reception method according to claim 3, further comprising the steps of:
receiving instruction information instructing correction of the attribute information from the network terminal; and
storing the received instruction information.
9. The printing order reception method according to claim 3, further comprising the steps of:
receiving instruction information instructing correction of the attribute information from the network terminal;
regenerating the print image in accordance with the received instruction information; and
transmitting the regenerated print image to the network terminal.
10. The printing order reception method according to claim 3, further comprising the steps of:
receiving instruction information instructing correction of the attribute information from the network terminal; and
generating the print data in accordance with the received instruction information.
11. The printing order reception method according to claim 2, wherein the print image is the same as the print data.
12. The printing order reception method according to claim 1, further comprising the steps of:
storing attribute information of the print content data used to print the first type of printing medium; and
generating the print data by using at least a part of the stored attribute information.
13. The printing order reception method according to claim 12, further comprising the step of:
copying at least a part of the attribute information as second attribute information.
14. The printing order reception method according to claim 13, further comprising the step of:
generating the print data by using the second attribute information.
15. The printing order reception method according to claim 12, further comprising the step of:
generating the print image by using the attribute information and attribute information stored in advance and used for the generation of the print data.
16. A printing order reception apparatus for accepting an order of a printed matter via a network comprising:
a print content data storage unit for storing print content data used when printing a first type of printing medium;
a print data generation unit for employing the print content data stored by the print content data storage unit to generate print data to be printed on a second type of printing medium; and
an external apparatus transmission unit for transmitting the print data generated by the print data generation unit to an external device.
17. The printing order reception apparatus according to claim 16, further comprising:
a print image generation unit for generating a print image to be printed on the second type of printing medium; and
a network terminal transmission unit for transmitting the print image generated by the print image generation unit to a network terminal.
18. The printing order reception apparatus according to claim 17, further comprising an attribute information storage unit for storing attribute information of the print content data,
wherein the print image generation unit generates the print image by using at the least a part of the attribute information stored in the attribute information storage unit.
19. The printing order reception apparatus according to claim 18, further comprising a copying unit for copying at least a part of the attribute information as second attribute information.
20. The printing order reception apparatus according to claim 19, wherein the print image generation unit employs the second attribute information to generate the print image.
21. The printing order reception apparatus according to claim 19, further comprising:
an instruction information acceptance unit for accepting instruction information instructing correction of the second attribute information from the network terminal; and
a second attribute information correction unit for correcting the second attribute information in accordance with the instruction information accepted by the instruction information acceptance unit.
22. The printing order reception apparatus according to claim 18, wherein the print image generation unit generates the print image by using the attribute information and attribute information stored in advance and used for the generation of the print data.
23. The printing order reception apparatus according to claim 18, further comprising:
an instruction information acceptance unit for receiving instruction information instructing correction of the attribute information from the network terminal; and
an instruction information storage unit for storing the instruction information received by the instruction information acceptance unit.
24. The printing order reception apparatus according to claim 18, further comprising:
an instruction information acceptance unit for receiving instruction information instructing correction of the attribute information from the network terminal; and
a print image regeneration unit for regenerating the print image in accordance with the instruction information received by the instruction information acceptance unit,
wherein the network terminal transmission unit transmits the print image regenerated by the print image regeneration unit to the network terminal.
25. The printing order reception apparatus according to claim 18, further comprising an instruction information acceptance unit for receiving instruction information instructing correction of the attribute information from the network terminal,
wherein the print data generation unit generates the print data in accordance with the instruction information received by the instruction information acceptance unit.
26. The printing order reception apparatus according to claim 17, wherein the print image is the same as the print data.
27. The printing order reception apparatus according to claim 16, further comprising an attribute information storage unit for storing attribute information of the print content data used to print the first type of printing medium,
wherein the print data generation unit generates the print data by using at least a part of the attribute information stored in the attribute information storage unit.
28. The printing order reception apparatus according to claim 27, further comprising a copying unit for copying at least a part of the attribute information as second attribute information.
29. The printing order reception apparatus according to claim 28, wherein the print data generation unit employs the second attribute information to generate the print data.
30. The printing order reception apparatus according to claim 27, further comprising a print image generation unit for generating the print image by using the attribute information and attribute information stored in advance and used for the generation of the print data.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A composition comprising a chemical combination of a photodynamic tetra-pyrrolic compound having a porphyrin or chlorin structure having four pendant groups attached to at least one pyrolle ring, said compound being provided with a plurality of radionuclide element atoms connected to a plurality of functional groups that will complex or combine with an MR imaging enhancing element or ion selected from the group consisting of \u2014(CH2)2CONHphenyleneCH2DTPA; \u2014CH2CH2CON(CONHphenylene-CH2DTPA)2
such that the compound may be used to enhance MR imaging wherein \u2014CH2CH2CON(CONHphenylene-CH2DTPA)2 counts as two such functional groups.
2. The composition of claim 1 wherein the radionuclide element is selected from the group consisting of Technetium99, Indium111, radioactive iodine and a Lanthanum series element including Gadolinium.
3. The composition of claim 1 wherein the radionuclide element forms cations and the compound is a chelate of the radionuclide element with the porphyrin or chlorin structure.
4. The composition of claim 1 wherein the radionuclide element forms anions and the compound is a direct chemical combination of the radionuclide element with a porphyrin or chlorin structure.
5. A compound having the structural formula:
where R1, R2, R2a R3, R3a R4, R5, R5a R6, R7, R7a, and R8 cumulatively contain at least two functional groups that complex or combine with an MR imaging enhancing element or ion; R1 is \u2014CH\u2550CH2, \u2014CHO, COOH,
where R9=\u2014OR10 where R10 is lower alkyl of 1 through 8 carbon atoms, \u2014((CH2)2O)nCH3 where n is 0 through 3, or \u2014(CH2)2CONHphenyleneCH2DTPA; R2, R2a, R3, R3a, R4, R5, R5a, R7, and R7a are independently hydrogen, lower alkyl or substituted lower alkyl so as to contain a functional group that will combine with a radionuclide element selected from the group consisting of Technetium99, Indium111, radioactive iodine and a Lanthanum series element including Gadolinium or two R2, R2a, R3, R3a, R5, R5a, R7, and R7a groups on adjacent carbon atoms may be taken together to form a covalent bond or two R2, R2a, R3, R3a, R5, R5a, R7, and R7a groups on the same carbon atom may form a double bond to a divalent pendant group; R2 and R3 may together form a 5 or 6 membered heterocyclic ring containing oxygen, nitrogen or sulfur; R6 is \u2014CH2\u2014, \u2014NR11\u2014 or a covalent bond; R8 is \u2014(CH2)2CO2CH3, \u2014(CH2)2CONHphenyleneCH2DTPA, \u2014CH2CH2CON(CONHphenyleneCH2DTPA)2, \u2014CH2R11 or
where R11 is
and polynuclide complexes thereof; wherein the functional groups that will complex or combine with an MR imaging enhancing element or ion are selected from the group consisting of \u2014(CH2)2CONHphenyleneCH2DTPA; \u2014CH2CH2CON(CONHphenyleneCH2DTPA)2;
wherein \u2014CH2CH2CON(CONHphenylene-CH2DTPA)2 counts as two such functional groups.
6. The compound of claim 5 wherein the compound is a dinuclide complex of gadolinium III.
7. The compound of claim 6 where R8 is \u2014CH2CH2CON(CONHphenyleneCH2DTPA)2.
8. The compound of claim 7 wherein R2, R2a, R3, R3a, R4, R5, R5a, R7, and R7a are independently hydrogen or lower alkyl of 1 through 4 carbon atoms, R1 is
and R9 is \u2014O-hexyl.
9. A compound of the formula:
where R1 is \u2014CH\u2550CH2, \u2014CHO, COOH, or
where R9=\u2014OR10 where R10 is lower alkyl of 1 through 8 carbon atoms, \u2014((CH2)2O)nCH3 where n is 0 through 3, or \u2014(CH2)2CONHphenyleneCH2DTPA; R2, R2a, R3, R3a, R7, and R7a are independently hydrogen, lower alkyl or substituted lower alkyl so as to contain a functional group that will combine with a radionuclide element is selected from the group consisting of Technetium99, Indium111, radioactive iodine and a Lanthanum series element including Gadolinium or two R2, R2a, R3, R3a, R7, and R7a groups on adjacent carbon atoms may be taken together to form a covalent bond or two R2, R2a, R3, R3a, R7, and R7a groups on the same carbon atom may form a double bond to a divalent pendant group; and R6 is \u2014CH2\u2014, \u2014NR11\u2014 or a covalent bond where R11 is lower alkyl of 1 through 6 carbon atoms; and R12 is \u2014COORa where Ra is hydrogen or lower alkyl of 1 through 8 carbon atoms; and dinuclide complexes thereof; wherein the functional groups that will complex or combine with an MR imaging enhancing element or ion are selected from the group consisting of \u2014(CH2)2CONHphenyleneCH2DTPA; \u2014CH2CH2CON(CONHphenylene-CH2 DTPA)2;
and
10. The compound of claim 9 where the compound is a digadolinium III complex.
11. The compound of claim 9 where R2 is \u2014CH3 and R3 is \u2014CH2CH3.
12. The compound or complex of claim 9 where R6 is \u2014NR11\u2014 where R11 is hexyl.
13. A di-technetium99m complex of the compound of claim 1.
14. A di-indium111 complex of the compound of claim 1.
15. The compound of claim 1 that is a di-99mTc complex of a bisaminoethanethiol derivative of HPPH.
16. The compound of claim 1 that is HPPH-di-Gd(III)di-aminophenylDTPA.
17. The compound of claim 1 that is purpurin 18 imide-di-Gd(III)di-aminophenylDTPA.
18. The compound of claim 1 that is a di-Gd(III)di-aminophenylDTPA derivative of bacteriochlorin.
19. The compound of claim 5 wherein the compound is a dicomplex of radionuclide element technetium99m, indium111 or gadolinium III.
20. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 1 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
21. The method of claim 20 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
22. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 3 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
23. The method of claim 22 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
24. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 5 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
25. The method of claim 24 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
26. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 6 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
27. The method of claim 26 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
28. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 7 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
29. The method of claim 28 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
30. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 8 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
31. The method of claim 30 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
32. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 9 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
33. The method of claim 32 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
34. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 10 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
35. The method of claim 34 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
36. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 11 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
37. The method of claim 36 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
38. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 11 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
39. The method of claim 38 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
40. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 12 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
41. The method of claim 40 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
42. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 16 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
43. The method of claim 42 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
44. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 17 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
45. The method of claim 44 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
46. A method for the detection of tumors that comprises injecting from about 5 to about 20 \u03bcmolkg of body weight of the compound of claim 18 into a mammal followed by MR imaging of the mammal to locate and visualize the tumors.
47. The method of claim 46 wherein the tumor is exposed to light at the absorption frequency of the compound after MR imaging at a sufficient intensity to cause tumor necrosis.
48. The compound of claim 1 where the compound is a digadolinium III complex.