Author: claimsbot

1. An optical plate, comprising at least an optical plate unit, each optical plate unit comprising a light output surface, and a bottom surface opposite to the light output surface, a plurality of first protrusions formed at the bottom surface, and a lamp-receiving portion defined at the bottom surface.
2. The optical plate according to claim 1, wherein the first protrusions are selected from the group consisting of V-shaped protrusions, conical protrusions, pyramidal protrusions, frustum of cone, and frustum of pyramid.
3. The optical plate according to claim 2, wherein a width of each of the V-shaped protrusions is in a range from about 0.025 millimeters to about 2 millimeters; and an apex angle of each of the V-shaped protrusions is in a range from about 60 degrees to about 120 degrees.
4. The optical plate according to claim 3, wherein an apex angle of each of the V-shaped protrusions is in a range from about 60 degrees to about 120 degrees.
5. The optical plate according to claim 4, wherein edges of each of the V-shaped protrusions are smoothed, and a radius of the smoothed edges is equal to or less than about 1.1 millimeters.
6. The optical plate according to claim 1, wherein the first protrusions are arranged regularly at the bottom surface in a matrix manner.
7. The optical plate according to claim 1, wherein the lamp-receiving portion is one of a through hole and a blind hole.
8. The optical plate according to claim 1, wherein the lamp-receiving portion is in the middle of the optical plate.
9. The optical plate according to claim 1, wherein each optical plate unit further comprises a plurality of second protrusions formed on the light output surface.
10. A backlight module, comprising:
a housing having a base and a plurality of sidewalls extending from a periphery of the base;
at least a point light source having a light output portion located on the base;
a light diffusion plate positioned on a top of the sidewalls; and
an optical plate comprising at least an optical plate unit, each optical plate unit comprising a light output surface, and a bottom surface opposite to the light output surface, a plurality of first protrusions formed on the bottom surface, and a lamp-receiving portion defined on the bottom surface, wherein the light output portion is received in the lamp-receiving portion.
11. The backlight module according to claim 10, wherein the point light source is a light emitting diode, and the backlight module further comprises a reflective member that is positioned on the light output portion of the point light source, or on the light output surface of the optical plate above the lamp-receiving portion.
12. The backlight module according to claim 10, wherein the first protrusions are selected from the group consisting of V-shaped protrusions, conical protrusions, pyramidal protrusions, frustum of cone, and frustum of pyramid.
13. The backlight module according to claim 12, wherein a width of each of the V-shaped protrusions in a range from about 0.025 millimeters to about 2 millimeters, an apex angle of each of the V-shaped protrusions in a range from about 60 degrees to about 120 degrees.
14. The backlight module according to claim 13, wherein edges of each of the V-shaped protrusions are smoothed, and a radius of the smoothed edges is equal to or less than about 1.1 millimeters.
15. The backlight module according to claim 10, wherein the first protrusions are arranged regularly at the bottom surface in a matrix manner.
16. The backlight module according to claim 10, wherein the lamp-receiving portion is one of a through hole and a blind hole.
17. The backlight module according to claim 10, wherein each optical plate unit further comprises a plurality of second protrusions formed at the light output surface.
18. The backlight module according to claim 10, wherein the optical plate comprises a plurality of optical plate units, the optical plate units arranged side by side.
19. The backlight module according to claim 10, wherein each optical plate unit further comprises a reflective module engaged with the housing, and a bottom board of the reflective module adjoins to the bottom surface of the optical plate.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method for locking a medical exam in a workflow queue for a clinical user, the method comprising:
authenticating the clinical user during a user session;
obtaining a user selection of the medical exam in the workflow queue during the user session;
associating a permission level to a session user identifier associated with the user session;
determining whether the permission level includes clearance to lock the medical exam; and
in response to determining that the permission level includes clearance to lock the medical exam, flagging the medical exam as read-only, wherein the flagged medical exam remains flagged after the clinical user ends the user session.
2. A method as defined in claim 1, further comprising:
populating a user interface with a listing of medical exams in the workflow queue, the listing of medical exams including the flagged medical exam and an unflagged medical exam, and wherein populating the user interface further comprises:
displaying a first icon associated with the flagged medical exam; and
displaying a second icon associated with the unflagged medical exam.
3. A method as defined in claim 2, wherein the flagged medical exam is a first flagged medical exam, the workflow queue is a first workflow queue for a first clinical user, the user interface is a first user interface, the listing of medical exams is a first listing of medical exams, and the method further comprising:
populating a second user interface with a second listing of medical exams in a second workflow queue for a second clinical user, the second listing of medical exams including the first listing of medical exams and a second flagged medical exam, and wherein populating the second user interface further comprises associating the first icon with the second flagged medical exam.
4. A method as defined in claim 3, wherein the user selection is a hover action, the method further comprising:
obtaining the user selection of the first flagged medical exam; and
displaying the session user identifier.
5. A method as defined in claim 4, wherein the user selection is a first user selection, the session user identifier is a first session user identifier, and the method further comprising:
obtaining a second user selection of the second flagged medical exam; and
displaying a second session user identifier associated with the second clinical user.
6. A method as defined in claim 1, wherein the medical exam is flagged in a persistent database.
7. A method as defined in claim 1, further comprising appending the session user identifier to the flagged medical exam.
8. A method as defined in claim 1, wherein the user selection further comprises toggling a lock flag to a first position.
9. A method as defined in claim 1, wherein the user session is a first user session, the method further comprising populating a user interface with the flagged medical exam during a second user session, the second user session initiated after the first user session ends.
10. A method as defined in claim 9, wherein the user selection is a first user selection, the session user identifier is a first session user identifier associated with the first user session, and the permission level is a first permission level, the method further comprising:
obtaining a second user selection during the second user session, the second user selection corresponding to unlocking the flagged medical exam;
identifying a second session user identifier associated with the second user session;
determining whether the second session user identifier matches the first session user identifier; and
in response to determining that the second session user identifier matches the first session user identifier, unflagging the flagged medical exam as read-only.
11. A method as defined in claim 10, further comprising:
in response to determining that the second session user identifier does not match the first session user identifier, associating a second permission level to the second session user identifier;
determining whether the second permission level includes clearance to unlock the flagged medical exam; and
in response to determining that the second permission level includes clearance to unlock the flagged medical exam, unflagging the flagged medical exam as read-only.
12. A method as defined in claim 10, wherein unflagging the flagged medical exam enables editing of the unflagged medical exam by another clinical user.
13. A method as defined in claim 9, wherein the first user session is initiated at a first institution and the second user session is initiated at a second institution.
14. A system to lock a medical exam in a workflow queue for a clinical user, the system comprising:
an input handler to obtain a user selection of the medical exam in the workflow queue during a user session;
a session user handler to:
authenticate the clinical user during the user session;
associate a permission level to a session user identifier associated with the user session; and
determine whether the permission level includes clearance to lock the medical exam; and

a flag locker to, in response to a determination that the permission level includes clearance to lock the medical exam, flag the medical exam as read-only, and wherein the flagged medical exam remains flagged after the clinical user ends the user session.
15. A system as defined in claim 14, further comprising:
a database parser to facilitate populating a user interface with a listing of medical exams in the workflow queue, the listing of medical exams to include the flagged medical exam and an unflagged medical exam; and
an output handler to display on the user interface a first icon associated with the flagged medical exam, and the output handler to display on the user interface a second icon associated with the unflagged medical exam.
16. A system as defined in claim 15, wherein the flagged medical exam is a first flagged medical exam, the workflow queue is a first workflow queue for a first clinical user, the user interface is a first user interface, the listing of medical exams is a first listing of medical exams, and the system further comprising:
the database parser to facilitate populating a second user interface with a second listing of medical exams in a second workflow queue for a second clinical user, the second listing of medical exams to include the first listing of medical exams and a second flagged medical exam; and
a flag modifier to associate the first icon with the second flagged medical exam.
17. A system as defined in claim 14, wherein the flag locker is to flag the medical exam as read-only in a persistent database.
18. A machine readable storage medium comprising instructions that, when executed, cause a machine to at least:
authenticate a clinical user during a user session;
obtain a user selection of a medical exam in a workflow queue for the clinical user during the user session;
associate a permission level to a session user identifier associated with the user session;
determine whether the permission level includes clearance to lock the medical exam; and
in response to a determination that the permission level includes clearance to lock the medical exam, flag the medical exam as read-only, wherein the flagged medical exam remains flagged in a persistent database after the clinical user ends the user session.
19. A machine readable storage medium as defined in claim 18, wherein the user session is a first user session, and wherein the instructions further cause the machine to populate a user interface with the flagged medical exam during a second user session, the second user session to be initiated after the first user session ends.
20. A machine readable storage medium as defined in claim 19, wherein the user selection is a first user selection, the session user identifier is a first session user identifier associated with the first user session, and the permission level is a first permission level, and wherein the instructions further cause the machine to:
obtain a second user selection during the second user session, the second user selection to correspond to unlocking the flagged medical exam;
identify a second session user identifier associated with the second user session;
determine whether the second session user identifier matches the first session user identifier; and
in response to a determination that the second session user identifier matches the first session user identifier, unflag the flagged medical exam as read-only.
21. A machine readable storage medium as defined in claim 20, wherein unflagging the flagged medical exam enables flagging of the unflagged medical exam by another clinical user.

What is claimed is:

1. A method for augmenting an immune response in a patient comprising the step of administering an amount of flt3-ligand to the patient sufficient to generate an increase in the number of the patient’s dendritic cells.
2. A method according to claim 1, further comprising the step of administering one or more of the molecules selected from the group consisting of GM-CSF, IL-4, TNF-, IL-3, c-kit ligand, and fusions of GM-CSF and IL-3.
3. A method for augmenting an immune response in a patient having an infectious disease, comprising the step of administering of administering flt3-ligand in an amount sufficient to generate an increase in the number of the patient’s dendritic cells.
4. A method according to claim 3, further comprising the step of administering one or more of the molecules selected from the group consisting of GM-CSF, IL-4, TNF-, IL-3, c-kit ligand, and fusions of GM-CSF and IL-3.
5. A method according to claim 3, wherein the infectious disease is HIV.
6. A method for augmenting an immune response in a patient having a cancerous or neoplastic disease, comprising the step of administering flt3-ligand in an amount sufficient to generate an increase in the number of the patient’s dendritic cells.
7. A method according to claim 6, further comprising the step of administering one or more of the molecules selected from the group consisting of GM-CSF, IL-4, TNF-, IL-3, c-kit ligand, and fusions of GM-CSF and IL-3.
8. A preparation of dendritic cells having at least two cell surface markers selected from the group consisting of CD1a, HLA-DR and CD86, produced by contacting hematopoietic stem or progenitor cells with flt3-ligand.
9. A dendritic cell preparation according to claim 8 produced further by contacting the hematopoietic stem or progenitor cells with a molecule selected from the group consisting of GM-CSF, IL-4, TNF-, IL-3, c-kit ligand, and fusions of GM-CSF and IL-3.
10. An antigen-expressing dendritic cell population produced by the process of
(a) contacting hematopoietic stem or progenitor cells with flt3-ligand in an amount sufficient to generate a dendritic cell population;
(b) either (i) exposing the dendritic cells to an antigen-specific peptide or (ii) transfecting the dendritic cells with a gene encoding an antigen-specific peptide;
(c) allowing the dendritic cells to process and express the antigen; and
(d) purifying the antigen-expressing dendritic cells.
11. A dendritic cell population according to claim 10 wherein step (a) of the process further comprises contacting the hematopoietic stem or progenitor cells with a molecule selected from the group consisting of GM-CSF, IL-4, TNF-, IL-3, c-kit ligand, and fusions of GM-CSF and IL-3.
12. A method of driving hematopoietic stem or progenitor cells to a dendritic cell lineage comprising contacting such hematopoietic stem or progenitor cells with flt3-ligand.
13. A method of preparing an antigen-presenting dendritic cell population comprising the steps of:
(a) contacting hematopoietic stem or progenitor cells with flt3-ligand in an amount sufficient to generate a dendritic cell population;
(b) either (i) exposing the dendritic cells to an antigen-specific peptide or (ii) transfecting the dendritic cells with a gene encoding an antigen-specific peptide;
(c) allowing the dendritic cells to process and express the antigen; and
(d) purifying the antigen-expressing dendritic cells.
14. A method according to claim 13, wherein step (a) further comprises contacting the hematopoietic stem or progenitor cells with a molecule selected from the group consisting of GM-CSF, IL-4, TNF-, IL-3, c-kit ligand, and fusions of GM-CSF and IL-3.
15. A method of preparing antigen-specific T cells comprising the steps of:
(a) contacting hematopoietic stem or progenitor cells with flt3-ligand in an amount sufficient to generate a dendritic cell population;
(b) either (i) exposing the dendritic cells to an antigen-specific peptide or (ii) transfecting the dendritic cells with a gene encoding an antigen-specific peptide;
(c) allowing the dendritic cells to process and express the antigen; and
(d) allowing the dendritic cells to present the antigen to T cells.
16. A method of enhancing a mammal’s immune response to a vaccine antigen, comprising the steps of administering to such mammal an immunogenic amount of the vaccine antigen and an immunogenicity-augmenting amount of flt3-ligand in concurrent or sequential combination with such vaccine antigen.
17. A vaccine adjuvant comprising a molecule selected from the group consisting of c-kit ligand and flt3-ligand.
18. A method for inducing tolerance of graft tissue in a host, comprising administering flt3-ligand to the host in an amount sufficient to increase the number of dendritic cells.
19. A dendritic cell expansion media comprising an effective amount of flt3-ligand and a cytokine selected from the group consisting of IL-3, IL-4, GM-CSF, TNF, C-Kit ligand and GM-CSFIL-3 fusion proteins.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method for determining a characteristic of an electrochemical test strip comprising
(A) providing a test strip having an electrical connector at a first end, an electrochemical test cell at a second opposite end, a waveguide extending from the first end towards the second end, and a deflector formed in or on the waveguide, said deflector suitable for deflecting at least a portion of light traveling along the waveguide so that the deflected light exits the waveguide between the first end and second end of the strip;
(B) inserting the first end of the strip into an apparatus, said apparatus comprising a light source and a photodetector, said light source being disposed to introduce light into the first end of the waveguide and said photodetector being disposed to detect the deflected light exiting the waveguide;
(C) directing light into the waveguide;
(D) detecting the deflected light exiting the waveguide; and
(E) correlating the detected light with a characteristic.
2. The method of claim 1 wherein the waveguide extends to the second end of the strip and wherein light exits the waveguide at the second end of the strip.
3. The method of claim 1 wherein the characteristic is regional identification.
4. The method of claim 1 wherein the characteristic is calibration information.
5. The method of claim 1 wherein the characteristic is the type of analyte measured by the test strip.
6. The method of claim 1 wherein the characteristic is alignment of the test strip with the apparatus.
7. The method of claim 1 wherein a plurality of deflectors are formed in or on the waveguide and the photodetector detects light deflected by the plurality of deflectors as separate signals.
8. The method of claim 1 wherein the apparatus comprises an analyte test meter having a strip port connector for interaction with the electrical connector of the test strip and having electronics to determine an amount of an analyte in a sample applied to the electrochemical test cell of the test strip and wherein the photodetector and the photogenerator are contained in the analyte test meter.
9. The method of claim 1 wherein said test strip further comprises a top substrate and a bottom substrate; wherein the waveguide is sandwiched between the two substrates.
10. The method of claim 1 wherein said test strip further comprises
a top substrate;
a bottom substrate;
wherein said electrical connector electrically connects the electrochemical test cell with a strip port connector of a meter and comprises a first tab formed at the first end of the top substrate layer, and a second tab formed at the first end of the bottom substrate layer;
wherein the first tab is small in width relative to the second tab; and
wherein the first tab is not aligned with the second tab.
11. An elongated test strip comprising
an electrical connector at a first end,
an electrochemical test cell at a second opposite end,
a waveguide extending from the first end towards the second end, and
a deflector formed in or on the waveguide, wherein said deflector is suitable for deflecting at least a portion of light traveling along the waveguide so that the deflected light exits the waveguide between the first end and second end of the strip.
12. The test strip of claim 11 wherein one or more additional deflectors are formed in or on the waveguide.
13. A combination of the test strip of claim 11 and an analyte test meter wherein the analyte test meter detects light exiting the deflector formed in or on the waveguide and correlates detected light with a characteristic of the strip.
14. The combination of claim 13 wherein the characteristic is regional identification.
15. The combination of claim 13 wherein the characteristic is calibration information.
16. The combination of claim 13 wherein the characteristic is the type of analyte measured by the test strip.
17. The combination of claim 13 wherein the characteristic is alignment of the test strip with the analyte test meter.
18. An elongated test strip comprising
(a) a first deflector surface and a second deflector surface;
(b) an optical waveguide disposed between the first and second deflector surfaces extending from a first end towards a second end of the test strip, whereby light cast into the waveguide at the first end is emitted from the waveguide at the second end;
(b) an strip port connector disposed at the first end; and
(c) an electrochemical test cell disposed at the second end;
wherein a first deflector is formed in the optical waveguide, a second deflector is formed in the first deflector surface and a second deflector is formed in the second deflector surface;
wherein the first, second, and third deflectors are aligned;
wherein said deflectors are not contiguous with the electrochemical cell; and
further comprising a reflective material placed over the second deflector such that light is directed back through the first, second, and third deflectors.
19. The test strip of claim 18 wherein one or more additional deflectors are formed in the waveguide andor the first deflector surface andor bottom surface; and wherein said deflectors are not contiguous with the electrochemical cell.
20. The test strip of claim 18 having at least one characteristic and an deflector pattern corresponding to said characteristic.
21. The test strip of claim 20 wherein the characteristic is regional identification.
22. The test strip of claim 20 wherein the characteristic is calibration information.
23. The test strip of claim 20 wherein the characteristic is the type of analyte measured by the test strip.
24. The test strip of claim 18 wherein the deflector indicates alignment of the test strip.
25. An elongated test strip comprising
(a) a top surface;
(b) a bottom surface;
(c) an optical waveguide disposed between the top and bottom surfaces and extending from a first end towards a second end of the test strip, whereby light cast into the waveguide at the first end is emitted from the waveguide at the second end;
(d) an electrical connector for connection to a meter disposed at the first end; and
(e) an electrochemical test cell disposed at the second end;
wherein a first deflector and a second deflector are formed in the optical waveguide, a third deflector is formed in the top surface and a fourth deflector is formed in the bottom surface;
wherein the third and fourth deflectors are not aligned;
wherein the first and third deflectors are aligned and the second and fourth deflectors are aligned; and
wherein said deflectors are not contiguous with the electrochemical cell.
26. The test strip of claim 25 wherein said first and second deflectors are aligned.
27. The test strip of claim 25 having a first plurality of deflectors on the top surface and a second plurality of deflectors on the bottom surface; and wherein said deflectors are not contiguous with the electrochemical cell.
28. The test strip of claim 25 having at least one characteristic and a deflector pattern corresponding to said characteristic.
29. The test strip of claim 28 wherein the characteristic is that the test strip is not counterfeit.
30. The test strip of claim 28 wherein the characteristic is regional identification.
31. The test strip of claim 28 wherein the characteristic is calibration information.
32. The test strip of claim 28 wherein the characteristic is the type of analyte measured by the test strip.
33. The test strip of claim 25 wherein the deflector indicates alignment of the test strip.
34. A combination of a test strip and a test meter, wherein
(a) said test strip comprises
an electrical connector at a first end,
an electrochemical test cell at a second opposite end,
a waveguide extending from the first end towards the second end, and
a deflector formed in or on the waveguide, wherein said deflector is suitable for deflecting at least a portion of light traveling along the waveguide so that the deflected light exits the waveguide between the first end and second end of the strip,

(b) said test meter comprises
a strip port connector for interaction with the electrical connector of the test strip,
electronics to determine an amount of an analyte in a sample applied to the electrochemical test cell of the test strip, and
a photogenerator for generating and directing light into the first end of the waveguide are contained in the analyte test meter,
a photodetector for detecting deflected light exiting the waveguide,

wherein the first end of the test strip is disposed in the strip port connector of the test meter.
35. The test strip of claim 34 wherein one or more additional deflectors are formed in or on the waveguide, wherein said deflectors are not contiguous with the electrochemical cell.
36. A test strip comprising
(a) a top substrate extending the full length of the strip;
(b) a bottom substrate extending the full length of the strip;
(c) an electrical connector for connection to a meter disposed at a first end; and
(d) an electrochemical test cell disposed at a second end;
wherein said electrical connector comprises a first tab formed at the first end of the top substrate, and a second tab formed at the first end of the bottom substrate;
wherein the first tab is small in width relative to the second tab;
wherein the first tab is not aligned with the second tab;
wherein the test strip further comprises an optical waveguide disposed between the top and bottom surfaces and extending from the first end towards the second end of the test strip, whereby light cast into the waveguide at the first end is emitted from the waveguide at the second end; and
wherein a first deflector is formed in the optical waveguide such that light exiting the waveguide via the deflector is visible through a surface of the strip.
37. The test strip of claim 36 wherein the second tab is notched in the middle of the tab.
38. The test strip of claim 36 wherein the second tab is notched on the edge closest to the first tab.
39. The test strip of claim 36 wherein the second tab is notched on the edge farthest from the first tab.
40. A set of test strips of claim 36 further comprising a plurality of subgroups wherein all test strips in the same subgroup detect the same analyte and are prepared in a single manufacturing process and wherein notches are formed in the second tab of all or all but one of the subgroups to distinguish between subgroups.
41. A test strip comprising
(a) a top surface;
(b) a bottom surface;
(c) two edges;
(d) an optical waveguide disposed between the top and bottom surfaces and extending from a first end towards a second end of the test strip, whereby light cast into the waveguide at the first end is emitted from the waveguide at the second end;
(e) an electrical connector for connection to a meter disposed at the first end; and
(f) an electrochemical test cell disposed at the second end;
(g) an deflector punched through the optical waveguide such that light exiting the optical waveguide exits through an edge of the test strip.
42. An electrochemical test strip comprising:
an electrical connector with a plurality of electrical contact areas disposed at a first end;
an electrochemical test cell;
a waveguide extending from the first end toward second end of the strip; and
a plurality of apertures formed through the waveguide between the first and second ends, wherein said apertures deflect a portion of light traveling along the waveguide so that the deflected light exits the test strip through the apertures, and wherein at least one aperture is of different size than another aperture.
43. The test strip of claim 42, wherein the waveguide extends to the second end of the strip and wherein light exits the waveguide at the second end of the strip.
44. A method for determining a characteristic of an electrochemical test strip, the method comprising:
(A) providing a test strip comprising: an electrical connector with a plurality of electrical contact areas disposed at a first end; an electrochemical test cell; a waveguide extending from the first end towards a second end of the strip; and a plurality of apertures formed through the waveguide between the first and second ends, wherein said apertures deflect a portion of light traveling along the waveguide so that the deflected light exits the test strip through the apertures, and wherein at least one aperture is of different size than another aperture;
(B) directing light into the waveguide and detecting the location and intensity of the deflected light exiting the test strip through the apertures; and
(C) determining a characteristic of the electrochemical test strip, from the deflected light detected in step (B).
45. The method of claim 44, further comprising the step of: (D) making electrical contact with the plurality of contact areas of the test strip,
wherein the characteristic of step (C) is further determined from the electrical contacts made in step (D).
46. The method of claim 44, wherein the waveguide extends to the second end of the strip and wherein light exits the waveguide at the second end of the strip.
47. The method of claim 44, wherein the characteristic is regional identification, calibration information, counterfeit information, analyte information, test strip alignment information, brand information, manufacturer information, or any combination thereof.