1460741945-0e1a3bf8-a5d9-45ac-bb15-74ac28e7fd61

1. A method for processing a commercial financial transaction between a customer and a merchant, the commercial financial transaction including a check used by the customer for making a purchase from the merchant, said method performed using a computer coupled to a database, said method comprising:
approving the customer electronically on the computer, by an originator, for receiving a financing package for engaging in the commercial financial transaction with the merchant;
electronically storing within the database approved customer data that is associated with the approved customer;
issuing the financing package to the approved customer from the originator, the financing package including the check having a plurality of security features and a security agreement between the customer and the originator associated therewith;
electronically storing within the database financing package data that is associated with the approved customer;
receiving, electronically at the computer, first purchase data associated with the commercial financial transaction from the merchant, the first purchase data including data relating to the security agreement, the check, and a product or service purchased by the customer, the security agreement executed by the customer establishing for the originator a security interest associated with the product or service purchased by the customer, the check executed by the customer establishing a financing agreement between the customer and the originator;
performing an initial verification of the commercial financial transaction electronically on the computer including comparing the financing package data to the first purchase data; and
electronically processing the commercial financial transaction if the initial verification is satisfied.
2. A method in accordance with claim 1, wherein approving the customer comprises approving the customer based on data stored in the database, the data received from at least one of a plurality of merchants, a plurality of customers, and public databases having information relating to previous transactions by the plurality of customers.
3. A method in accordance with claim 2, wherein approving the customer further comprises determining a risk score for the customer based on the data stored in the database, and wherein the approval of the customer is based on the risk score.
4. A method in accordance with claim 2, wherein approving the customer further comprises determining a maximum check amount that can be entered by at least one of the approved customer and the originator on the check for purchasing the product or service from the merchant.
5. A method in accordance with claim 1, wherein issuing the financing package comprises creating a financing package specific to at least one of the approved customer and the merchant.
6. A method in accordance with claim 1, wherein electronically storing financing package data within the database comprises transmitting the financing package data from the originator to an originator bank, wherein the financing package includes a maximum check amount that can be entered on the check for making the purchase from the merchant.
7. A method in accordance with claim 6, wherein performing an initial verification comprises transmitting the first purchase data from the originator to the originator bank.
8. A method in accordance with claim 7, wherein performing an initial verification further comprises:
comparing, by the originator bank, a check amount entered on the check for making the purchase to the maximum check amount; and
if the entered check amount is greater than the maximum check amount, transmitting an exception message from the originator bank to the originator such that the associated transaction can be further reviewed by the originator.
9. A method in accordance with claim 1, further comprising receiving second purchase data representative of the executed check at an originator bank after the executed check has been processed by the merchant and an acquiring bank used by the merchant.
10. A method in accordance with claim 9, wherein electronically processing the commercial financial transaction comprises performing a second verification of the commercial financial transaction by comparing the second purchase data to the first purchase data.
11. A method in accordance with claim 10, wherein performing the second verification of the commercial financial transaction comprises comparing a check amount included in the second purchase data to a check amount included in the first purchase data.
12. A method in accordance with claim 10, wherein performing the second verification of the commercial financial transaction comprises comparing an execution date included in the second purchase data to an execution date included in the first purchase data.
13. A method in accordance with claim 10, wherein performing the second verification of the commercial financial transaction comprises comparing a merchant identifier included in the second purchase data to a merchant identifier included in the first purchase data.
14. A method in accordance with claim 10, further comprising performing a third verification of the commercial financial transaction including comparing an execution date included in the second purchase data to a preselected stale date included in the financing package data.
15. A method in accordance with claim 1, further comprising paying, by the approved customer to the originator, an amount of the commercial financial transaction over a specified term at a specified interest rate.
16. A network-based system for processing a commercial financial transaction between a customer and a merchant, the commercial financial transaction including a check used by the customer for making a purchase from the merchant, said system comprising:
a client system;
a database for storing information; and
a server system configured to be coupled to said client system and said database, said server system configured to:
electronically prompt a user to approve the customer for receiving a financing package for engaging in the commercial financial transaction with the merchant, wherein the financing package is issued to the approved customer, the financing package including a check having a plurality of security features and a security agreement between the approved customer and an originator of the financing package;
store within said database approved customer data that is associated with the approved customer;
store within said database financing package data that is associated with the approved customer;
receive first purchase data associated with the commercial financial transaction from the merchant, the first purchase data including data relating to the security agreement, the check, and a product or service purchased by the approved customer, the security agreement executed by the approved customer establishing for the originator a security interest associated with the product or service purchased by the approved customer, the check executed by the approved customer establishing a financing agreement between the approved customer and the originator;
perform an initial verification of the commercial financial transaction that includes a comparison of the financing package data with the first purchase data; and
process data relating to the commercial financial transaction if the initial verification is satisfied.
17. A network-based system in accordance with claim 16, wherein said server system is further configured to generate a list of approved customers based on data stored in said database, the data received from at least one of a plurality of merchants and public databases having information relating to previous transactions by the approved customers included in the list of approved customers.
18. A network-based system in accordance with claim 17, wherein said server is further configured to determine a risk score for each approved customer included in the list of approved customers based on the data stored in said database, and wherein the approval is based on the risk score.
19. A network-based system in accordance with claim 17, wherein said server is further configured to determine a maximum check amount that can be entered by at least one of the approved customer of the list of approved customers and the originator on the check for purchasing the product or service from the merchant.
20. A network-based system in accordance with claim 17, wherein the financing package to be issued to each approved customer included in the list of approved customers is specific to at least one of the approved customer to which the financing package is issued and the merchant.
21. A network-based system in accordance with claim 16, wherein the financing package data includes a maximum check amount that can be entered on the check for making the purchase from the merchant.
22. A network-based system in accordance with claim 16, wherein said server is further configured to perform the initial verification by:
comparing a check amount entered on the check for making the purchase to the maximum check amount stored within said database; and
if the entered check amount is greater than the maximum check amount, generating an exception message such that the associated transaction can be further reviewed by the originator.
23. A network-based system in accordance with claim 16, wherein said server is further configured to receive second purchase data representative of the executed check after the executed check has been processed by the merchant and an acquiring bank used by the merchant.
24. A network-based system in accordance with claim 23, wherein said server is further configured to perform a second verification of the commercial financial transaction by comparing the second purchase data to the first purchase data.
25. A network-based system in accordance with claim 23, wherein said server is further configured to perform a second verification of the commercial financial transaction by comparing a check amount included in the second purchase data to a check amount included in the first purchase data.
26. A network-based system in accordance with claim 23, wherein said server is further configured to perform a second verification of the commercial financial transaction by comparing an execution date included in the second purchase data to an execution date included in the first purchase data.
27. A network-based system in accordance with claim 23, wherein said server is further configured to perform a second verification of the commercial financial transaction by comparing a merchant identifier included in the second purchase data to a merchant identifier included in the first purchase data.
28. A network-based system in accordance with claim 23, wherein said server is further configured to perform a third verification of the commercial financial transaction by comparing an execution date included in the second purchase data to a preselected stale date included in the financing package data.
29. A computer coupled to a database for processing a commercial financial transaction between a customer and a merchant, the commercial financial transaction including a check used by the customer for making a purchase from the merchant, said computer programmed to:
electronically prompt a user to approve the customer for receiving a financing package for engaging in the commercial financial transaction with the merchant, wherein the financing package is issued to the approved customer, the financing package including a check having a plurality of security features and a security agreement between the approved customer and an originator of the financing package;
store within said database approved customer data that is associated with the approved customer;
store within said database financing package data that is associated the approved customer;
receive first purchase data associated with the commercial financial transaction from the merchant, the first purchase data including data relating to the security agreement, the check, and a product or service purchased by the approved customer, the security agreement executed by the approved customer establishing for the originator a security interest associated with the product or service purchased by the approved customer, the check executed by the approved customer establishing a financing agreement between the approved customer and the originator;
perform an initial verification of the commercial financial transaction that includes a comparison of the financing package data with the first purchase data; and
process data relating to the commercial financial transaction if the initial verification is satisfied.
30. A computer in accordance with claim 29, wherein said computer is further programmed to generate a list of approved customers based on data stored in said database, the data received from at least one of a plurality of merchants and public databases having information relating to previous transactions by the approved customers included in the list of approved customers.
31. A computer in accordance with claim 30, wherein said computer is further programmed to determine a maximum check amount that can be entered by at least one of the approved customer of the list of approved customers and the originator on the check for purchasing the product or service from the merchant.
32. A computer in accordance with claim 30, wherein the financing package to be issued to each approved customer included in the list of approved customers is specific to at least one of the approved customer to which the financing package is issued and the merchant.
33. A computer in accordance with claim 29, wherein said computer is further programmed to perform the initial verification by:
comparing a check amount entered on the check for making the purchase to a maximum check amount stored within said database; and
if the entered check amount is greater than the maximum check amount, generating an exception message such that the associated transaction can be further reviewed by the originator.
34. A computer in accordance with claim 29, wherein said computer is further programmed to receive second purchase data representative of the executed check after the executed check has been processed by the merchant and an acquiring bank used by the merchant.
35. A computer in accordance with claim 34, wherein said computer is further programmed to perform a second verification of the commercial financial transaction by comparing the second purchase data to the first purchase data.
36. A computer in accordance with claim 34, wherein said computer is further programmed to perform a second verification of the commercial financial transaction by performing at least one of:
comparing a check amount included in the second purchase data to a check amount included in the first purchase data;
comparing an execution date included in the second purchase data to an execution date included in the first purchase data;
comparing a merchant identifier included in the second purchase data to a merchant identifier included in the first purchase data; and
comparing an execution date included in the second purchase data to a preselected stale date included in the financing package data.
37. A computer-readable storage medium having a computer program of instructions embodied thereon for processing a commercial financial transaction between a customer and a merchant, the commercial financial transaction including a check used by the customer for making a purchase from the merchant, said computer program of instructions executable by a computer for performing the steps comprising:
electronically approving the customer for receiving a financing package for engaging in the commercial financial transaction with the merchant, wherein the financing package is issued to the approved customer, the financing package including a check having a plurality of security features and a security agreement between the approved customer and an originator of the financing package;
storing approved customer data that is associated the approved customer;
storing financing package data that is associated with the approved customer;
receives first purchase data associated with the commercial financial transaction from the merchant, the first purchase data including data relating to the security agreement, the check, and a product or service purchased by the approved customer, the security agreement executed by the approved customer establishing for the originator a security interest associated with the product or service purchased by the approved customer, the check executed by the approved customer established a financing agreement between the approved customer and the originator;
performing an initial verification of the commercial financial transaction that includes a comparison of the financing package data with the first purchase data; and
processing data relating to the commercial financial transaction if the initial verification is satisfied.
38. A computer-readable storage medium in accordance with claim 37, wherein said computer program of instructions is executable by the computer for performing the step comprising generating a list of approved customers based on data received from at least one of a plurality of merchants and public databases having information relating to previous transactions by the approved customers included in the list of approved customers.
39. A computer-readable storage medium in accordance with claim 38, wherein said computer program of instructions is executable by the computer for performing the step comprising determining a maximum check amount that can be entered by at least one of the approved customer of the list of approved customers and the originator on the check for purchasing the product or service from the merchant.
40. A computer-readable storage medium in accordance with claim 37, wherein the financing package data includes a maximum check amount that can be entered on the check for making the purchase from the merchant.
41. A computer-readable storage medium in accordance with claim 37, wherein said computer program of instructions is executable by the computer for performing the step comprising performing the initial verification by:
comparing a check amount entered on the check for making the purchase to the maximum check amount; and
if the entered check amount is greater than the maximum check amount, generating an exception message such that the associated transaction can be further reviewed by the originator.
42. A computer-readable storage medium in accordance with claim 37, wherein said computer program of instructions is executable by the computer for performing the step comprising receiving second purchase data representative of the executed check after the executed check has been processed by the merchant and an acquiring bank used by the merchant.
43. A computer-readable storage medium in accordance with claim 42, wherein said computer program of instructions is executable by the computer for performing the step comprising performing a second verification of the commercial financial transaction by performing at least one of:
comparing the second purchase data to the first purchase data;
comparing a check amount included in the second purchase data to a check amount included in the first purchase data;
comparing an execution date included in the second purchase data to an execution date included in the first purchase data; and
comparing a merchant identifier included in the second purchase data to a merchant identifier included in the first purchase data.
44. A computer-readable storage medium in accordance with claim 42, wherein said computer program of instructions is executable by the computer for performing the step comprising performing a third verification of the commercial financial transaction by comparing an execution date included in the second purchase data to a preselected stale date included in the financing package data.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A coating composition comprising an acylated lecithin additive.
2. The coating composition according to claim 1, wherein the acylated lecithin is present in a concentration of between about 0.1 and about 10.0% by weight of the composition.
3. The coating composition according to claim 1, wherein the acylated lecithin is present in a concentration of between about 0.5 and about 5.0% by weight of the composition.
4. The coating composition according to claim 1, wherein the acylated lecithin is present in a concentration of between about 1.0 and about 5.0% by weight of the composition.
5. The coating composition according to claim 1, wherein the acylated lecithin is an acetylated lecithin additive.
6. The coating composition according to claim 1, wherein the lecithin additive is derived from soybean oil.
7. The coating composition according to claim 1, wherein the composition further comprises a titanium dioxide pigment.
8. The coating composition according to claim 1, further comprising an alkyd coating, a urethane coating, an unsaturated polyester coating, a latex coating or a water dispersible coating.
9. A flat-based water-dispersed coating composition, comprising a lecithin additive present in a concentration between about 0.5 and about 10.0% by weight of the composition, wherein the additive provides improved cleanability.
10. The coating composition of claim 9, wherein the lecithin additive is present in a concentration between about 1.0 and about 5.0% by weight of the composition.
11. The dried coating of claim 1.
12. The dried coating of claim 9.
13. The dried coating of claim 11, wherein the coating demonstrates improved cleanability by 50% or more.
14. The dried coating of claim 11, wherein the coating demonstrates improved cleanability by at least 1 point on a 0 to 10 scale.
15. The dried coating of claim 11, wherein the coating demonstrates improved cleanability by at least 2 points on a 0 to 10 scale.
16. The dried coating of claim 11, wherein the coating demonstrates improved cleanability by at least 3 points on a 0 to 10 scale.
17. A method of providing improved cleanability to a substrate comprising coating the substrate with a coating composition comprising a lecithin additive.
18. The method of claim 17, wherein the lecithin additive is an acylated lecithin additive.
19. The method of claim 18, wherein the acylated lecithin additive is an acetylated lecithin additive.

1460741936-ff45d4aa-f646-479e-a90c-faa291a968c2

What is claimed is:

1. A method of monitoring a thickness of a conductive layer in a substrate during a polishing operation, comprising:
positioning a substrate on a first side of a polishing surface;
generating an alternating magnetic field from an inductor positioned on a second side of the polishing surface opposite the substrate, the magnetic field extending through the polishing surface to induce eddy currents in the conductive layer; and
detecting a change in the alternating magnetic field caused by a change in the thickness of the conductive layer.
2. The method of claim 1, wherein generating the alternating magnetic field from an inductor includes driving a first coil with an oscillator at a first frequency.
3. The method of claim 2, wherein the first frequency is a resonant frequency when the substrate is not in proximity to the magnetic field.
4. The method of claim 2, wherein detecting a change in the alternating magnetic field includes sensing the alternating magnetic field with a second coil.
5. The method of claim 4, wherein the second coil is connected in parallel with a capacitor.
6. The method of claim 4, wherein the first coil is wound around a first portion of a core and the second coil is wound around a second portion of the core.
7. The method of claim 1, wherein generating the alternating magnetic field includes directing the magnetic field through a core positioned at least partially in a recess in a polishing pad.
8. The method of claim 1, further comprising determining when the inductor is adjacent the substrate.
9. The method of claim 8, wherein determining when the inductor is adjacent the substrate includes using an optical interrupter.
10. The method of claim 8, wherein determining when the inductor is adjacent the substrate includes using an encoder.
11. The method of claim 1, wherein generating an alternating magnetic field from an inductor includes driving the inductor with a first signal, and detecting a change in the alternating magnetic field includes generating a second signal from the alternating magnetic field.
12. The method of claim 11, further comprising determining a change in amplitude in the second signal.
13. The method of claim 11, further comprising determining a change in a phase difference between the first signal and the second signal.
14. A method of chemical mechanical polishing, comprising:
positioning a substrate having a conductive layer on a first side of a polishing surface;
generating an alternating magnetic field from an inductor positioned on a second side of the polishing surface opposite the substrate, the magnetic field extending through the polishing surface to induce eddy currents in the conductive layer;
creating relative motion between the substrate and the polishing surface to polish the conductive layer;
sensing the eddy currents in the substrate; and
halting polishing when the sensed eddy currents exhibit an endpoint criteria.
15. The method of claim 14, wherein the endpoint criteria comprises the eddy current signal passing a threshold strength.
16. The method of claim 14, wherein the endpoint criteria comprises a slope of the eddy current signal leveling off.
17. The method of claim 14, wherein the endpoint criteria comprises a change in slope of the eddy current signal.
18. The method of claim 14, wherein the endpoint criteria comprises a local minima or local maxima of the eddy current signal.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A compound of the formula I,
the racemic-diastereomeric mixtures, optical isomers, or pharmaceutically-acceptable salts thereof, wherein
the dotted line in the structure of formula (I) represents an optional double bond;
X is CR1; Y is N; Q is O;
R3 for each occurrence is independently hydrogen, hydroxy, substituted or unsubstituted alkyl or substituted or unsubstituted alkoxy;
R1 is
where Z100 is nitro, optionally substituted amino,
\u2003or a group optionally substituted with Rb selected from the group consisting of cycloalkyl, naphthyl, tetrahydronaphthyl, benzothienyl, furanyl, thienyl, benzoxazolyl, benzothiazolyl,
\u2003thiazolyl, benzofuranyl, 2,3-dihydrobenzofuranyl, indolyl, isoxazolyl, tetrahydropyranyl, tetrahydrofuranyl, piperidinyl, pyrazolyl, pyrrolyl, oxazolyl, isothiazolyl, oxadiazolyl, thiadiazolyl, indolinyl, indazolyl, benzoisothiazolyl, pyrido-oxazolyl, pyrido-thiazolyl, pyrimido-oxazolyl, pyrimido-thiazolyl and benzimidazolyl;
when a is 1 and D1, G1, J1, L1 and M1 are each independently selected from the group consisting of CRa and N, provided that at least two of D1, G1, J1, L1 and M1 are CRa; or
when a is 0, and one of D1, G1, L1 and M1 is NRa, one of D1, G1, L1 and M1 is CRa and the remainder are independently selected from the group consisting of CRa and N;
when b is 1 and D2, G2, J2, L2 and M2 are each independently selected from the group consisting of CRa and N, provided that at least two of D2, G2, J2, L2 and M2 are CRa; or
when b is 0, and one of D2, G2, L2 and M2 is NRa, one of D2, G2, L2 and M2 is CRa and the remainder are independently selected from the group consisting of CRa and N;

Ra and Rb each represent one or more substituents and are for each occurrence independently selected from the group consisting of hydrogen, halogen, \u2014CN, \u2014NO2, \u2014C(O)OH, \u2014C(O)H, \u2014OH, \u2014C(O)O-alkyl, \u2014Z105\u2014C(O)N(R)2, \u2014Z105\u2014N(R)\u2014C(O)\u2014Z200, \u2014Z105\u2014N(R)\u2014S(O)2\u2014Z200, \u2014Z105\u2014N(R)\u2014C(O)\u2014N(R)\u2014Z200, Rc, CH2ORe, tetrazolyl, trifluoromethylcarbonylamino, trifluoromethylsulfonamido, and an optionally substituted group selected from the group consisting of carboxamido, alkyl, alkoxy, aryl, alkenyl, aryloxy, heteroaryloxy, arylalkyl, alkynyl, amino, aminoalkyl, amido groups, heteroarylthio and arylthio;
Z105 for each occurrence is independently a covalent bond or (C1-C6) aliphatic;
Z200 for each occurrence is independently an optionally substituted (C1-C6) aliphatic, optionally substituted phenyl, or optionally substituted \u2014(C1-C6)-phenyl aliphatic group-phenyl;

Rc for each occurrence is independently hydrogen, optionally substituted alkyl, optionally substituted aryl, \u2014CH2\u2014NRdRe, \u2014W\u2014(CH2)t\u2014NRdRe, \u2014W\u2014(CH2)t\u2014Oalkyl, \u2014W\u2014(CH2)t\u2014S-alkyl or \u2014W\u2014(CH2)t\u2014OH;
Rd and Re for each occurrence are independently H, alkyl, alkanoyl or SO2-alkyl; or
Rd, Re and the nitrogen atom to which they are attached together form a five- or six-membered heterocyclic ring;
t for each occurrence is independently an integer from 2 to 6;
W for each occurrence is independently a direct bond or O, S, S(O), S(O)2, or NRf;
Rf for each occurrence is independently H or alkyl;

Z110 is a covalent bond, or an optionally substituted (C1-C6) aliphatic which is optionally substituted with one or more substituents selected from the group consisting of alkyl, CN, OH, halogen, NO2, COOH, optionally substituted amino and optionally substituted phenyl;
Z111 is a covalent bond, an optionally substituted (C1-C6) aliphatic or an optionally substituted \u2014(CH2)n-cycloalkyl-(CH2)n\u2014; where the optionally substituted groups are optionally substituted with one or more substituents selected from the group consisting of alkyl, CN, OH, halogen, NO2, COOH, optionally substituted amino and optionally substituted phenyl; or
R1 is a substituted or unsubstituted carbocyclic or heterocyclic ring fused with ring 2;
A is a covalent bond, \u2014O\u2014; \u2014S\u2014; \u2014S(O)p\u2014; \u2014N(R)\u2014; \u2014N(C(O)OR)\u2014; \u2014N(C(O)R)\u2014; \u2014N(SO2R)\u2014; \u2014CH2O\u2014; \u2014CH2S\u2014; \u2014CH2N(R)\u2014; \u2014CH(NR)\u2014; \u2014CH2N(C(O)R)\u2014; \u2014CH2N(C(O)OR)\u2014; \u2014CH2N(SO2R)\u2014; \u2014CH(NHR)\u2014; \u2014CH(NHC(O)R)\u2014; \u2014CH(NHSO2R)\u2014; \u2014CH(NHC(O)OR)\u2014; \u2014CH(OC(O)R)\u2014; \u2014CH(OC(O)NHR); \u2014CH\u2550CH\u2014; \u2014C(\u2550NOR)\u2014; \u2014C(O)\u2014; \u2014CH(OR)\u2014; \u2014C(O)N(R)\u2014; \u2014N(R)C(O)\u2014; \u2014N(R)S(O)p\u2014; \u2014OC(O)N(R)\u2014; \u2014N(R)\u2014C(O)\u2014(CH2), \u2014N(R)\u2014, \u2014N(R)C(O)O\u2014; \u2014N(R)\u2014(CH2)n+1\u2014C(O)\u2014, \u2014S(O)pN(R)\u2014; \u2014N(C(O)R)S(O)p\u2014; \u2014N(R)S(O)pN(R)\u2014; \u2014N(R)\u2014C(O)\u2014(CH2)n\u2014O\u2014, \u2014C(O)N(R)C(O)\u2014; \u2014S(O)pN(R)C(O)\u2014; \u2014OS(O)pN(R)\u2014; \u2014N(R)S(O)pO\u2014; \u2014N(R)S(O)pC(O)\u2014; \u2014SOpN(C(O)R)\u2014; \u2014N(R)SOpN(R)\u2014; \u2014C(O)O\u2014; \u2014N(R)P(ORg)O\u2014; \u2014N(R)P(ORg)\u2014; \u2014N(R)P(O)(ORg)O\u2014; \u2014N(R)P(O)(ORg)\u2014; \u2014N(C(O)R)P(ORg)O\u2014; \u2014N(C(O)R)P(ORg)\u2014; \u2014N(C(O)R)P(O)(ORg)O\u2014, or \u2014N(C(O)R)P(ORg)\u2014;
p is 1 or 2;
R for each occurrence is independently H, optionally substituted alkyl, optionally substituted arylalkyl or optionally substituted aryl;
Rg for each occurrence is independently H, or an optionally substituted group selected from the group consisting of alkyl, arylalkyl, cycloalkyl and aryl; or
R, Rg, the nitrogen atom and the phosphorus atom, together form a five- or six-membered heterocyclic ring when R and Rg are in a phosphorus containing group; or
A is NRSO2 and R, Ra and the nitrogen atom together form an optionally substituted five- or six-membered heterocyclic ring fused to ring 1; and
n for each occurrence is independently an integer from 0 to 6.
2. A compound according to claim 1 of formula (III),
wherein
A is selected from the group consisting of a covalent bond, \u2014N(R)C(O)\u2014, and \u2014N(R)\u2014C(O)\u2014(CH2)n\u2014N(R)\u2014;
Z100 is selected from the group consisting of nitro, amino, substituted amino, and optionally substituted aryl;
R is hydrogen; and n is 0.
3. The compound of claim 2 wherein
A is a covalent bond; and Z100 is selected from the group consisting of nitro, amino and substituted amino.
4. The compound of claim 3 selected from the group consisting of 3-(4-nitrophenyl)isoxazolo5,4-dpyrimidin-4-amine; and 3-(4-aminophenyl)isoxazolo5,4-dpyrimidin-4-amine.
5. The compound of claim 2 wherein
A is selected from the group consisting of \u2014N(R)C(O)\u2014, and \u2014N(R)\u2014C(O)\u2014(CH2)n\u2014N(R)\u2014; and Z100 is optionally substituted aryl.
6. The compound of claim 5 selected from the group consisting of
N-4-(4-aminoisoxazolo5,4-dpyrimidin-3-yl)phenyl-N\u2032-(3-methylphenyl)urea;
N-4-(4-aminoisoxazolo5,4-dpyrimidin-3-yl)phenyl-N\u2032-(3-ethylphenyl)urea;
N-4-(4-aminoisoxazolo5,4-dpyrimidin-3-yl)phenyl-N\u2032-(3-chlorophenyl)urea;
N-4-(4-aminoisoxazolo5,4-dpyrimidin-3-yl)phenylbenzamide;
N-4-(4-aminoisoxazolo5,4-dpyrimidin-3-yl)phenyl-N\u2032-3-(trifluoromethyl)phenylurea; and
N-4-(4-aminoisoxazolo5,4-dpyrimidin-3-yl)phenyl-N\u2032-2-fluoro-5-(trifluoromethyl)phenylurea.
7. A pharmaceutical composition comprising a compound according to claim 1 and a pharmaceutically acceptable carrier or diluent.