Author: claimsbot

1. A process for producing a compound represented by the Formula (II\u2032):
wherein Ra is a hydrogen atom or a substituent, Ar is an aromatic hydrocarbon group which may have a substituent, Y is a hydrogen atom or a substituent, a ring B is a nitrogen-containing ring which may have a substituent, n is an integer of 1 to 3 or a salt thereof, which comprises reducing a compound represented by the Formula (III\u2032):
wherein R is an ester residue and each symbol is defined above or a salt thereof.
2. A process for producing a compound represented by the Formula (II):
wherein Ra is a hydrogen atom or a substituent, Ar is an aromatic hydrocarbon group which may have a substituent, Y1 and Y2 are, the same or different and independently, a hydrogen atom or a substituent, a ring B is a nitrogen-containing ring which may have a substituent, n is an integer of 1 to 3 or a salt thereof, which comprises reducing in the presence of a metal hydride complex and a metal halide compound a compound represented by the Formula (III):
wherein R is an ester residue and each symbol is defined above or a salt thereof.
3. The process according to claim 1 or 2, wherein the Ring B is a heterocyclic ring which may have a substituent and one to three heteroatoms arbitrarily selected from a nitrogen atom, a sulfur atom, and an oxygen atom other than the nitrogen atom indicated in the formula.
4. A process for producing a compound represented by the Formula (IIa):
wherein Ar is an aromatic hydrocarbon group which may have a substituent, Y1 and Y2 are, the same or different and independently, a hydrogen atom or a substituent, Rb is a protection group, n is an integer of 1 to 3 or a salt thereof, which comprises reducing a compound represented by the Formula (IIIa):
wherein R is an ester residue and each symbol is defined above or a salt thereof in the presence of a metal hydride complex and a metal halide compound.
5. A process for producing a compound represented by the Formula (IIb):
wherein Y1 and Y2 are, the same or different and independently, a hydrogen atom or a substituent, Rb is a protection group, n is an integer of 1 to 3 or a salt thereof, which comprises reducing a compound represented by the Formula (IIIb):
wherein R is an ester residue and each symbol is defined above or a salt thereof in the presence of a metal hydride complex and a metal halide compound.
6. The process according to claim 2, wherein the metal hydride complex is an alkali metal hydride complex.
7. The process according to claim 6, wherein the alkali metal hydride complex is sodium borohydride.
8. The process according to claim 2, wherein the metal halide is a calcium halide.
9. The process according to claim 8, wherein the calcium halide is calcium chloride.
10. The process according to claim 1, wherein ether and alcohol are used as a solvent in a reduction reaction.
11. The process according to claim 10, which comprises adding alcohol to a reaction system in ether as a solvent.
12. The process according to claim 10 or 11, wherein the ether is a cyclic ether and the alcohol is C1-6 alcohol.
13. The process according to claim 12, wherein the cyclic ether is tetrahydrofuran and the C1-6 alcohol is ethanol or methanol.
14. A process for producing:
a compound represented by the Formula (II\u2032):
wherein Ra is a hydrogen atom or a substituent, Ar is an aromatic hydrocarbon group which may have a substituent, Y is a hydrogen atom or a substituent, a ring B is a nitrogen-containing ring which may have a substituent, n is an integer of 1 to 3 or a salt thereof;
a compound represented by the Formula (II):
wherein Ra is a hydrogen atom or a substituent, Ar is an aromatic hydrocarbon group which may have a substituent, Y1 and Y2 are, the same or different and independently, a hydrogen atom or a substituent, a ring B is a nitrogen-containing ring which may have a substituent, n is an integer of 1 to 3 or a salt thereof;
a compound represented by the Formula (IIa):
wherein Ar is an aromatic hydrocarbon group which may have a substituent, Y1 and Y2 are, the same or different and independently, a hydrogen atom or a substituent, Rb is a protection group, n is an integer of 1 to 3 or a salt thereof;
or

a compound represented by the Formula (IIb):
wherein Y1 and Y2 are, the same or different and independently, a hydrogen atom or a substituent, Rb is a protection group, n is an integer of 1 to 3 or a salt thereof,
which comprises selectively reducing (i) an esterified carboxyl group and (ii) an esterified carboxy group of a compound having an N-unsubstituted amino group or an N-monosubstituted amino group in an ether-alcohol solvent in the presence of metal hydride complex and a calcium halide.
15. The process according to claim 14, which comprises adding alcohol to a reaction system in ether as a solvent.
16. The process according to claim 14, wherein the metal hydride complex is an alkali metal hydride complex.
17. The process according to claim 14, wherein the calcium halide is calcium chloride.
18. The process according to claim 14, wherein the metal hydride complex is sodium borohydride, the calcium halide is calcium chloride, the ether is tetrahydrofuran, and the alcohol is ethanol or methanol.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

What is claimed is:

1. An in-plane switching mode liquid crystal display (LCD), comprising:
a first substrate having a switching element;
a second substrate;
a first electrode and a second electrode on the first substrate;
a transparent electrode asymmetrically overlapping the first electrode; and
a liquid crystal layer between the first substrate and the second substrate.
2. The in-plane switching mode LCD as claimed in claim 1, wherein the first electrode is a common electrode and the second electrode is a data electrode.
3. The in-plane switching mode LCD as claimed in claim 1, wherein the switching device is a transistor including:
a gate electrode on the first substrate;
a gate insulating layer on the gate electrode and the first substrate;
a semiconductor layer on the gate insulating layer; and
source and drain electrodes on the semiconductor layer.
4. The in-plane switching mode LCD as claimed in claim 1, wherein the switching device is a transistor including a gate electrode, a source electrode and a drain electrode.
5. The in-plane switching mode LCD as claimed in claim 4, wherein the transistor includes a gate insulating film on the first substrate and the first electrode, the second electrode being formed on the gate insulating film.
6. The in-plane switching mode LCD as claimed in claim 5, wherein the gate insulating film is formed on the gate electrode and the gate electrode is on the same layer as the first electrode.
7. The in-plane switching mode LCD as claimed in claim 1, further comprising a protection film between the transparent electrode and the second electrode and wherein the first electrode, the second electrode and the transparent electrode are all on different layers.
8. The in-plane switching mode LCD as claimed in claim 1, further comprising a shielding electrode on the second substrate, the first and second electrodes and the shielding electrode forming a tilted electric field.
9. The in-plane switching mode LCD as claimed in claim 8, wherein the shielding electrode is a black matrix.
10. The in-plane switching mode LCD as claimed in claim 8, wherein the shielding electrode includes chrome (Cr).
11. The in-plane switching mode LCD as claimed in claim 1, wherein the transparent electrode shields an electric field between the second electrode and a data line.
12. The in-plane switching mode LCD as claimed in claim 1, wherein the transparent electrode includes ITO.
13. The in-plane switching mode LCD as claimed in claim 1, wherein the first electrode has an outmost portion and the transparent electrode is asymmetrical with respect to the outermost portion of the first electrode.
14. An in-plane switching mode liquid crystal display comprising:
a first substrate having a switching element;
a second substrate;
a plurality of first electrodes including an outermost first electrode on the first substrate;
a plurality of second electrodes on the first substrate;
a gate insulating film, a protection film, and a transparent film sequentially stacked on the outermost first electrode, wherein the transparent film at least partially covers the outermost first electrode; and
a liquid crystal layer between the first substrate and the second substrate.
15. The in-plane switching mode LCD as claimed in claim 14, wherein the first electrodes and the second electrodes are on planes different from each other.
16. The in-plane switching mode LCD as claimed in claim 15, wherein the second electrodes are on the gate insulating film.
17. The in-plane switching mode LCD as claimed in claim 14, wherein the transparent film includes indium tin oxide (ITO).
18. The in-plane switching mode LCD as claimed in claim 14, further comprising a shielding electrode on the second substrate, wherein the shielding electrode forms a tilted electric field together with the first and second electrodes.
19. The in-plane switching mode LCD as claimed in claim 14, wherein the transparent film shields an electric field between the second electrode and a data line.
20. An in-plane switching mode liquid crystal display device comprising:
a first substrate having a switching element;
a second substrate;
a first electrode on the first substrate;
a gate insulating film on an entire surface of the first substrate including the first electrode;
a second electrode on the gate insulating film, the second electrode forming an in-plane electric field together with the first electrode;
a protection film on the first electrode and the second electrode;
an asymmetric transparent electrode on the protection film; and
a liquid crystal layer between the first substrate and the second substrate.
21. The in-plane switching mode liquid crystal display device as claimed in claim 20, further comprising a shielding electrode on the second substrate, wherein the shielding electrode forms a tilted electric field together with the first electrode and the second electrode.
22. The in-plane switching mode liquid crystal display device as claimed in claim 21, wherein the shielding electrode is a black matrix.
23. The in-plane switching mode liquid crystal display device as claimed in claim 21, wherein the black matrix is a Cr.
24. The in-plane switching mode liquid crystal display device as claimed in claim 20, wherein the first electrode is a common electrode and the second electrode is a data electrode.
25. The in-plane switching mode liquid crystal display device as claimed in claim 20, wherein the transparent electrode includes indium tin oxide (ITO).
26. The in-plane switching mode liquid crystal display device as claimed in claim 20, wherein the common electrode has an outmost portion and the transparent electrode is on top of the outermost portion of the common electrode, the transparent electrode is asymmetrical.
27. An in-plane switching liquid crystal display (LCD) device comprising:
a first substrate and a second substrate;
a thin film transistor having a gate electrode, a source electrode and a drain electrode on the first substrate;
a liquid crystal material between the first and second substrate;
a common electrode on a first portion of the first substrate;
a data electrode on a second portion of the first substrate; and
a transparent electrode over a region of the first substrate, the region including at least a portion of the common electrode.
28. The in-plane switching liquid crystal display device of claim 27, wherein the transparent electrode has a first part at a first height above the first substrate and a second part at a second height above the first substrate.
29. The in-plane switching liquid crystal display device of claim 27, wherein the first part overlaps the common electrode and the second height does not overlap the common electrode.
30. The in-plane switching liquid crystal display device of claim 29, wherein the first part of the transparent electrode is higher than the second part of the transparent electrode.
31. The in-plane switching liquid crystal display device of claim 27, further comprising a shielding electrode on the second substrate.
32. The in-plane switching liquid crystal display device of claim 31, wherein the shielding electrode is a black matrix.
33. The in-plane switching mode liquid crystal display as claimed in claim 32, wherein the black matrix is a Cr.
34. The in-plane switching mode liquid crystal display device as claimed in claim 27, wherein the transparent electrode includes indium tin oxide (ITO).
35. The in-plane switching mode liquid crystal display as claimed in claim 27, further comprising a protection film over the first substrate, including the common and data electrodes, the protection film being between the common electrode and the transparent electrode.
36. An in-plane switching liquid crystal display (LCD) device comprising:
a first substrate;
a second substrate;
a thin film transistor including:
a gate electrode on the first substrate;
a gate insulating layer on the gate electrode;
a semiconductor layer on the gate insulating layer; and
a source electrode and a drain electrode on the semiconductor layer;
a gate line connected to the gate electrode extending in a first direction;
a data line connected to one of the source and drain electrodes extending in a second direction, the gate line and the data line defining a pixel region;
a common electrode on the first substrate on the same layer as the gate line and gate electrode and spaced from the gate electrode;
a data electrode connected to one of the source and drain electrodes on the gate insulating film and spaced from the common electrode;
a protection film on the thin film transistor;
a field distorting electrode on the protection film overlapping at least a portion of the common electrode, the field distorting electrode preventing vertical crosstalk caused by the data line and the data electrode;
a black matrix on the second substrate; and
a liquid crystal material between the first and second orientation films.
37. The in-plane switching liquid crystal display device as claimed in claim 36, wherein the field distorting electrode including first and second portions.
38. The in-plane switching liquid crystal display device as claimed in claim 37, wherein the first portion overlaps the common electrode and the second portion does not overlap the common electrode.
39. The in-plane switching liquid crystal display device as claimed in claim 37, wherein the first portion is above the second portion.
40. The in-plane switching liquid crystal display device as claimed in claim 36, wherein the field-distorting electrode includes a transparent conductive material.
41. The in-plane switching liquid crystal display device as claimed in claim 40, wherein the transparent conductive material includes indium tin oxide.
42. The in-plane switching liquid crystal display device as claimed in claim 36, wherein the field distorting electrode forms an electric field with the data line, the data electrode and the black matrix.
43. The in-plane switching liquid crystal display device as claimed in claim 36, wherein the protection film covers the common electrode and the data electrode.
44. The in-plane switching liquid crystal display device as claimed in claim 36, further comprising a first orientation film on the protection film and the field distorting electrode.
45. The in-plane switching liquid crystal display device as claimed in claim 44, further comprising:
a color filter layer on the second substrate; and
a second orientation film on the color filter layer.
46. The in-plane switching liquid crystal display device as claimed in claim 44, further comprising an overcoat layer between the color filter layer and the second orientation film.
47. The in-plane switching liquid crystal display device as claimed in claim 36, the field distorting electrode shields an electric field between the data line and the data electrode.
48. A method of manufacturing an in-plane switching liquid crystal display (LCD) device comprising:
forming a thin film transistor including:
forming a gate electrode on a first substrate;
forming a gate insulating layer on the gate electrode;
forming a semiconductor layer on the gate insulating layer; and
forming a source electrode and a drain electrode on the semiconductor layer;
forming a gate line connected to the gate electrode extending in a first direction;
forming a data line connected to one of the source and drain electrodes extending in a second direction, the gate line and the data line defining a pixel region;
forming a common electrode on the first substrate on the same layer as the gate line and gate electrode and spaced from the gate electrode;
forming a data electrode connected to one of the source and drain electrodes on the gate insulating film and spaced from the common electrode;
forming a protection film on the thin film transistor, the common electrode and the data electrode;
forming a field distorting electrode on the protection film overlapping at least a portion of the common electrode, the field distorting electrode preventing vertical crosstalk caused by the data line and the data electrode; and
forming a first orientation film on the protection film and the field-distorting electrode.
49. The method as claimed in claim 48, further comprising:
forming a black matrix on a second substrate;
forming a color filter layer on the second substrate;
forming a second orientation film on the color filter layer; and
forming a liquid crystal material between the first and second orientation films.
50. The method as claimed in claim 48, wherein the field distorting electrode including first and second portions.
51. The method as claimed in claim 50, wherein the first portion overlaps the common electrode and the second portion does not overlap the common electrode.
52. The method as claimed in claim 50, wherein the first portion is above the second portion.
53. The method as claimed in claim 48, wherein the field-distorting electrode includes a transparent conductive material.
54. The method as claimed in claim 52, wherein the transparent conductive material includes indium tin oxide.
55. The method as claimed in claim 48, wherein the field distorting electrode forms an electric field with the data line, the data electrode and the black matrix.
56. The method as claimed in claim 48, wherein the field distorting electrode shields an electric field between the data line and the data electrode.

1. An isolated polynucleotide comprising a nucleotide sequence which hybridizes under stringent conditions to a sequence selected from the group consisting of SEQ ID NOS: 1-6010.
2. An isolated polynucleotide comprising at least 15 contiguous nucleotides of a nucleotide sequence having at least 90% sequence identity to a sequence selected from the group consisting of:
SEQ ID NOS: 1-6010, a degenerate variant of SEQ ID NOS: 1-6010, an antisense of SEQ ID NOS: 1-6010, and a complement of SEQ ID NOS: 1-6010.
3. An isolated polynucleotide comprising at least 15 contiguous nucleotides of a nucleotide sequence selected from the group consisting of: SEQ ID NOS:1-6010, a degenerate variant of SEQ ID NOS:1-6010, an antisense of SEQ ID NOS:1-6010, and a complement of SEQ ID NOS: 1-6010.
4. The isolated polynucleotide of claim 3, wherein the polynucleotide comprises at least 100 contiguous nucleotides of the nucleotide sequence.
5. The isolated polynucleotide of claim 3, wherein the polynucleotide comprises at least 200 contiguous nucleotides of the selected nucleotide sequence.
6. An isolated polynucleotide comprising a nucleotide sequence of at least 90% sequence identity to a sequence selected from the group consisting of: SEQ ID NOS: 1-6010, a degenerate variant of SEQ ID NOS:1-6010, an antisense of SEQ ID NOS:1-6010, and a complement of SEQ ID NOS:1-6010.
7. The isolated polynucleotide of claim 6, wherein the polynucleotide comprises a nucleotide sequence of at least 95% sequence identity to the selected nucleotide sequence.
8. The isolated polynucleotide of claim 6, wherein the polynucleotide comprises a nucleotide sequence that is identical to the selected nucleotide sequence.
9. A polynucleotide comprising a nucleotide sequence of an insert contained in a clone deposited as ATCC Accession No. PTA-2027, PTA-2028, PTA-2029, PTA-2030, PTA-2031, PTA-2032, PTA-2033, PTA-2034, PTA-2035, PTA-2036, PTA-2037, PTA-2038, PTA-2039, PTA-2040, PTA-2041, PTA-2042, PTA-2043, PTA-2044, PTA-2045, PTA-2046, PTA-2047, PTA-2050, PTA-2051, PTA-2052, PTA-2053, PTA-2054, PTA-2055, PTA-2056, PTA-2057, PTA-2058, PTA-2059, PTA-2060, PTA-2061, PTA-2062, PTA-2048, PTA-2049, PTA-2063, PTA-2064, PTA-2065, PTA-2066, PTA-2067, or PTA-2068.
10. An isolated cDNA obtained by the process of amplification using a polynucleotide comprising at least 15 contiguous nucleotides of a nucleotide sequence of a sequence selected from the group consisting of SEQ ID NOS: 1-6010.
11. The isolated cDNA of claim 10, wherein the polynucleotide comprises at least 25 contiguous nucleotides of the selected nucleotide sequence.
12. The isolated cDNA of claim 10, wherein the polynucleotide comprises at least 100 contiguous nucleotides of the selected nucleotide sequence.
13. The isolated cDNA of claims 10, 11, or 12, wherein amplification is by polymerase chain reaction (PCR) amplification.
14. An isolated recombinant host cell containing the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
15. An isolated vector comprising the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
16. A method for producing a polypeptide, the method comprising the steps of:
culturing a recombinant host cell containing the polynucleotide according to claims 1, 2, 3, 6, 9, or 10., said culturing being under conditions suitable for the expression of an encoded polypeptide;
recovering the polypeptide from the host cell culture.
17. An isolated polypeptide encoded by the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
18. An antibody that specifically binds the polypeptide of claim 17.
19. A method of detecting differentially expressed genes correlated with a cancerous state of a mammalian cell, the method comprising the step of:
detecting at least one differentially expressed gene product in a test sample derived from a cell suspected of being cancerous, where the gene product is encoded by a gene comprising an identifying sequence of at least one of SEQ ID NOS: 1-6010;
wherein detection of the differentially expressed gene product is correlated with a cancerous state of the cell from which the test sample was derived.
20. A library of polynucleotides, wherein at least one of the polynucleotides comprises the sequence information of the polynucleotide according to claims 1, 2, 3, 6, 9, or 10.
21. The library of claim 20, wherein the library is provided on a nucleic acid array.
22. The library of claim 20, wherein the library is provided in a computer-readable format.
23. A method of inhibiting tumor growth by modulating expression of a gene product, the gene product being encoded by a gene identified by a sequence selected from the group consisting of SEQ ID NOS:1-6010.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A portable data storage device with USB accessible biometrics processor comprising:
an embedded fingerprint biometrics processing unit and sensor, wherein the fingerprint biometrics processing unit is accessible externally by USB host and internally within the device;
a plurality of non-volatile solid state readwrite memories for data and information storage;
a processor unit for interfacing with the embedded fingerprint system, a USB host and the non-volatile solid state readwrite memories;
a data encryption or a data protection scheme for data and information safekeeping within the non-volatile solid state readwrite memories; and
an enrollment scheme for biometric fingerprint enrollment.
2. The portable data storage device of claim 1, wherein the authorization access to the data storage is only by authorized fingerprints.
3. The portable data storage device as in claim 1, wherein a micro-controller and the embedded fingerprint biometric processing unit within the device are employed so as to authorize the read and write access of the non-volatile solid state readwrite memories.
4. The portable data storage device of claim 1, wherein bio-data for authentication of any unauthorized access to the non-volatile solid state readwrite memories is stored within the device.
5. The portable data storage device of claim 4, wherein the bio-data is inaccessible by the USB host.
6. The portable data storage device of claim 4, wherein users fingerprint bio-data include master fingerprint bio-data and normal user fingerprint bio-data, and the master user is able to erase the bio-data of both the master and the normal user, while the normal user is only able to erase his own bio-data.
7. The portable data storage device of claim 1, wherein an enrollment switch is used to differentiate fingerprint enrollment and normal device authentication operation.
8. A method of using a biometric parameters protected portable data storage device, said method comprising the steps of:
scanning user’s fingerprint by a fingerprint sensor;
processing the scanned fingerprint image by a biometrics processing unit which verifies the image with the user(s) fingerprint bio-data which is in a bio-data storage unit; and
requesting another fingerprint for scanning again from the user if the verification fails.
9. The portable data storage device of claim 1, wherein the typical biometrics verification and system access time is not more than 1 second.
10. The portable data storage device of claim 1, wherein the biometrics enrollment time is not more than 1 second per user, and not more than 10 users are assigned for authority access right.
11. The portable data storage device of claim 1, wherein the memories of the nonvolatile solid stage readwrite memories include flash memories.
12. The portable data storage device of claim 11, wherein the memories of the nonvolatile solid stage readwrite memories are magneto-resistive random access memories commonly (MRAM).
13. The portable data storage device as in claim 2, wherein a micro-controller and the embedded fingerprint biometric processing unit within the device are employed so as to authorize the read and write access of the non-volatile solid state readwrite memories.
14. The portable data storage device of claim 2, wherein bio-data for authentication of any unauthorized access to the non-volatile solid state readwrite memories is stored within the device.