Author: claimsbot

1. An apparatus comprising:
a phase frequency detector to accept a reference signal and a feedback signal from a feedback loop;
a charge pump coupled to the phase frequency detector, the charge pump to be activated in an operational mode;
a voltage controlled oscillator coupled to the phase frequency detector to accept a control signal from the phase frequency detector and to provide an output clock based on the control signal, the output signal having a frequency;
a frequency detection module for comparison of the frequency of the output signal of the voltage controlled oscillator to a predetermined frequency, and, thereafter, to provide a control signal based on the comparison; and
a frequency divider coupled to the phase frequency detector and to the voltage controlled oscillator to provide the feedback signal to the phase frequency detector, the control signal to enable or disable the feedback loop based on the comparison.
2. The apparatus of claim 1, further comprising a pull up voltage module to be disabled in an operational mode.
3. The apparatus of claim 1, wherein the frequency detection module comprises a state machine.
4. The apparatus of claim 1, wherein the frequency divider is disabled in a start up mode and enabled in an operational mode.
5. A method comprising:
applying a bias voltage to bias a voltage controlled oscillator, the bias voltage causing the voltage controller oscillator to create a predetermined target frequency on an output;
detecting an output frequency of the biased voltage controlled oscillator on the output;
comparing the detected output frequency to a predetermined threshold frequency;
disabling a feedback signal to the voltage controlled oscillator based on results of the comparing;
disabling the bias voltage on the results of the comparing; and
resetting a frequency counter in response to the output frequency being less than the predetermined threshold frequency.
6. The method of claim 5, further comprising synchronizing a reference clock with a VCO clock in response to a feedback divider being reset.
7. The method of claim 5, further comprising terminating a start up mode in response to the output frequency of the voltage controlled oscillator reaching the predetermined threshold frequency, wherein the terminating the startup mode comprises activating a charge pump.
8. The method of claim 5, further comprising terminating a start up mode in response to the output frequency of the voltage controlled oscillator reaching the predetermined threshold frequency, wherein the terminating comprises disabling a pull up module.
9. The method of claim 5, further comprising terminating a start up mode in response to the output frequency of the voltage controlled oscillator reaching the predetermined threshold frequency, wherein the terminating the startup mode comprises disabling a frequency counter module.
10. The method of claim 6, wherein the divider completes counting from one reference clock edge to the next and the feedback signal toggles indicating that the VCO has reached a target frequency.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A memory embodying a program of machine-readable instructions executable by a digital processing apparatus of a computer system to perform operations for controlling a graphical user interface system, where the graphical user interface system is capable of displaying multiple parent portlets in a single graphical user interface, the operations comprising:
displaying a page comprised of more than one parent portlets;
receiving a command to surface, at least one child sub-portlet from each of the more than one parent portlets displayed on the page;
surfacing the at least one child sub-portlet from each of the more than one parent portlets displayed on the page;

launching a management portlet on the displayed page for each of the more than one parent portlets having a surfaced at least one child sub-portlet, where the management portlet comprises controls for managing portlet operations relating to a parent portlet and the surfaced least one child sub-portlet of the portlet, where the management portlet operations comprise minimizing portlets, maximizing portlets, closing portlets, and surfacing portlets, singularly or on a group basis; and
displaying at least one graphical indicator comprising a collapser control and a connecting link tying a particular parent portlet of the more than one parent portlet, displayed on the page, to the at least one child sub-portlet surfaced from the particular parent portlet, where physical proximity and indentation are used in addition to the at least one graphical indicator to show a relation between the parent portlet, the management portlet, and the at least one child sub-portlet surfaced from the particular parent portlet.
2. The memory of claim 1 where the at least one child sub-portlet surfaced from a particular parent portlet of the more than one parent portlets displayed on the page is further displayed in a table-like structure within the management portlet launched on the displayed page for the particular parent portlet.
3. The memory of claim 1 where the at least one graphical indicator further comprises applying a similar background color to a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet, where the similar background color indicates that the particular parent portlet and child sub-portlet are related.
4. The memory of claim 1 where the at least one graphical indicator further comprises applying a similar shading to a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet, where the similar shading indicates that the particular parent portlet and child sub-portlet are related.
5. The memory of claim 1 where the at least one graphical indicator comprises incorporating a similar pattern somewhere in both a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet, where the pattern is unique to the particular parent portlet and any child sub-portlet launched from the parent portlet.
6. The memory of claim 5 where the similar pattern comprises hash marks in the title fields of a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet.
7. The memory of claim 1 where the at least one graphical indicator comprises displaying a particular parent portlet of the more than one parent portlets and child sub-portlet surfaced from the particular parent portlet in close proximity to one another, while indenting the child sub-portlet in relation to the particular parent portlet.
8. The memory of claim 1 where the operations further comprise:
displaying a child sub-portlet management control inline to the graphical indicator for each of the more than one parent portlets on the page having a surfaced at least one child sub-portlet.
9. The memory of claim 8 where the child sub-portlet management control comprises a control for closing the child sub-portlet.
10. The memory of claim 9 where the operations further comprise:
receiving a command to close the child sub-portlet entered with the child sub-portlet management control; and
closing the child sub-portlet.
11. The memory of claim 8 where the child sub-portlet management control comprises a control for minimizing or maximizing the child sub-portlet.
12. The memory of claim 8 where the child sub-portlet management control comprises a control for resizing the child sub-portlet.
13. The memory of claim 1 where the management portlet operations further comprise a control to close all sub-portlets with a single action, even if a sub-portlet is currently hidden from view.
14. A computer system for displaying an interactive graphical user interface, the computer system comprising:
at least one memory to store at least one program of machine-readable instructions, where the at least one program performs operations to display the interactive graphical user interface when executed; and
at least one processor coupled to the at least one memory, where the at least one processor performs at least the following operations when the at least one program is executed:
displaying a page comprised of more than one parent portlets in the graphical user interface;
receiving a command to surface at least one child sub-portlet from each of the more than one parent portlets into the page; and
surfacing the at least one child sub-portlet from each of the more than one parent portlets into the page

launching a management portlet on the displayed page for each of the more than one parent portlets having a surfaced at least one child sub-portlet, where the management portlet comprises controls for managing portlet operations relating to a parent portlet and the surfaced at least one child sub-portlet of the parent portlet, where the management portlet operations comprise minimizing portlets, maximizing portlets, closing portlets, and surfacing portlets, singularly or on a group basis; and
displaying at least one graphical indicator comprising a collapser control and a connecting link tying a particular parent portlet or the more than one parent portlet, displayed on the page, to the at least one child sub-portlet surfaced from the particular parent portlet, where physical proximity and indentation are used in addition to the at least one graphical indicator to show a relation between the parent portlet, the management portlet, and the at least one child sub-portlet surfaced from the particular parent portlet.
15. The computer system of claim 14 where the at least one child sub-portlet surfaced from a particular parent portlet of the more than one parent portlets on the displayed page is further displayed in a table-like structure within the management portlet launched on the displayed page for the particular parent portlet.
16. The computer system of claim 14 where the at least one graphical indicator further comprises applying a similar background color to a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet, where the similar background color indicates that the particular parent portlet and the at least one child sub-portlet are related.
17. The computer system of claim 14 where the at least one graphical indicator further comprises applying a similar shading to a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet, where the similar shading indicates that the particular parent portlet and the at least one child sub-portlet are related.
18. The computer system of claim 14 where the at least one graphical indicator further comprises incorporating a similar pattern somewhere in both a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet, where the pattern is unique to the particular parent portlet and any child sub-portlet launched from the parent portlet.
19. The computer system of claim 18 where the similar pattern comprises hash marks in the title fields of a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet.
20. The computer system of claim 14 where the at least one graphical indicator further comprises displaying a particular parent portlet of the more than one parent portlets and the at least one child sub-portlet surfaced from the particular parent portlet in close proximity to one another, while indenting the child sub-portlet in relation to the particular parent portlet.
21. The computer system of claim 14 where the operations further comprise:
displaying a child sub-portlet management control inline to the graphical indicator for each of the more than one parent portlet on the page having a surfaced at least one child-portlet.
22. The computer system of claim of claim 14 further comprising:
parent portlet identification means for receiving a command to identify a particular parent portlet of the more than one parent portlet to which a child sub-portlet relates, and for identifying the particular parent portlet.
23. The computer system of claim 22 where the parent portlet identification means further comprises:
highlighting means for at least momentarily highlighting the particular parent portlet.
24. A user interface control system method comprising:
displaying on a display device of a computer system an interactive graphical user interface having portlet display capability, wherein a page displayed in the interactive graphical user interface comprises more than one parent portlet displayed on the graphical user interface;
receiving a command to surface at least one child sub-portlet from each of the more than one parent portlet; and
surfacing the at least one child sub-portlet into the page from each of the more than one parent portlet into the page;
launching a management portlet on the displayed page for each of the more than one parent portlets having a surfaced at least one child sub-portlet, where the management portlet comprises controls for managing portlet operations relating to a parent portlet and the surfaced at least one child sub-portlet of the parent portlet, where the management portlet operations comprise minimizing portlets, maximizing portlets, closing portlets, and surfacing portlets, singularly or on a group basis; and
displaying at least one graphical indicator comprising a collapser control and a connecting link tying a particular parent portlet of the more than one parent portlet, displayed on the page, to the at least one child sub-portlet surfaced from the particular parent portlet, where physical proximity and indentation are used in addition to the at least one graphical indicator to show a relation between the parent portlet, the management portlet, and the at least one child sub-portlet surfaced from the particular parent portlet.
25. The user interface control system method of claim 24 where the at least one child sub-portlet surfaced from a particular parent portlet of the more than one parent portlets on the displayed page is further displayed in a table-like structure within the management portlet launched on the displayed page for the particular parent portlet.
26. The user interface control system method of claim 24 where the at least one graphical indicator further comprises applying a similar background color to a particular parent portlet of the more than one parent portlets and child sub-portlet surfaced from the particular parent portlet, where the similar background color indicates that the parent portlet and the at least one child sub-portlet are related.
27. The user interface control system method of claim 24 where the at least one graphical indicator comprises applying a similar shading to a particular parent portlet of the more than one parent portlets and a least one child sub-portlet surfaced from the particular parent portlet, where the similar shading indicates that the parent portlet and the at least one child sub-portlet are related.
28. The user interface control system method of claim 24 where the at least one graphical indicator comprises incorporating a similar pattern somewhere in both a particular parent portlet of the more than one parent portlets and at least one child sub-portlet surfaced from the particular parent portlet, where the pattern is unique to the parent portlet and any child sub-portlet launched from the parent portlet.
29. The user interface control system method of claim 24 where the at least one graphical indicator comprises displaying a particular parent portlet of the more than one parent portlets and at least one child sub-portlet surfaced from the particular parent portlet in close proximity to one another, while indenting the at least one child sub-portlet in relation to the parent portlet.
30. A memory storing at least one machine readable program, where the least one machine readable program is executable by a processor to perform actions comprising:
displaying more than one parent portlets on a display page;
displaying more than one child sub-portlet on the page for each of the more than one parent portlets;
launching a management portlet on the page for each of the more than one parent portlets, where the management portlet is displayed between a particular parent portlet of the more than one parent portlet and the more than one child sub-portlet for the particular parent portlet, and where the management portlet comprises controls for managing portlet operations relating to the particular parent portlet and the more than one child sub-portlet of the particular parent portlet, where the management portlet operations consist of minimizing portlets, maximizing portlets, closing portlets, and surfacing portlets singularly or on a group basis, where the management control is operable to close all of the more than one child sub-portlets displayed for a particular parent portlet, and where the more than one child sub-portlet surfaced from a particular parent portlet of the more than one parent portlets on the displayed page is further displayed in a table-like structure within the management portlet;
displaying on the page, more than one graphical indicator comprising a collapser control and a connecting link tying a particular parent portlet of the more than one parent portlet, displayed on the page, to the at least one child sub-portlet surfaced from the particular parent portlet into the page, where the more than one graphical indicator comprises using physical proximity and indentation to show a relation between a particular parent portlet of the more than one parent portlet, the management portlet, and the more than one child sub-portlet surfaced from the particular parent portlet, and where the more than one graphical indicator further comprises applying similar identifiers consisting of a similar background color, a similar shading, a similar pattern, and similar hash marks to a particular parent portlet of the more than one parent portlets and the more than one child sub-portlet surfaced from the particular parent portlet, where the similar identifiers indicate that the particular parent portlet and the more than one child sub-portlet are related; and
displaying a child sub-portlet management control displayed on the page and inline to the graphical indicator for each of the more than one parent portlet on the page having a surfaced at least one child sub-portlet.

1. A dispenser for a volatile liquid, comprising:
a housing;
a fan mounted to the housing to generate an air stream;
a guide including a projection disposed on an inside surface of the housing provides at least one boundary in defining an opening in which the opening has a predetermined dimension to selectively receive a wick and to position the wick in alignment with the fan to immerse the wick into an air stream when the fan is activated.
2. The dispenser of claim 1, wherein the guide comprises two spaced apart projections extending from a surface of the housing.
3. The dispenser of claim 2, wherein the two projections are positioned in an interior portion of the housing.
4. The dispenser of claim 2, wherein the two projections extend in the general direction of the air stream generated by the fan.
5. The dispenser of claim 4, wherein the predetermined dimension is the distance between the two projections.
6. The dispenser of claim 2, wherein the guide includes a second set of spaced apart projections in which the two spaced apart projections and the second set of projections are spaced apart from one another.
7. The dispenser of claim 6, wherein the second set of spaced apart projections defines a second opening having a second pre-determined dimension to selectively receive and to position a portion of the wick in alignment with the fan.
8. The dispenser of claim 2, wherein the two spaced apart projections are positioned at an entrance of another opening defined in the housing.
9. The dispenser of claim 2, wherein the projections are positioned in the air stream generated by the fan.
10. The dispenser of claim 2, wherein the projection is positioned in an interior portion of the housing.
11. The dispenser of claim 2, wherein the two spaced apart projections extend in the general direction of the air stream generated by the fan.
12. The dispenser of claim 2, wherein the two spaced apart projections are positioned in the air stream generated by the fan.
13. The dispenser of claim 1, wherein the guide is integral with the housing.
14. The dispenser of claim 1, wherein the guide comprises a wall member surrounding the opening.
15. The dispenser of claim 14, wherein the wall member is positioned entirely around the opening.
16. The dispenser of claim 1, wherein the guide includes a wall member positioned to surround a top portion of the wick.
17. The dispenser of claim 16 wherein the wall member is positioned entirely around the top portion of the wick.
18. The dispenser of claim 1, wherein the opening of the guide is positioned relative to the fan to position the wick in alignment with a rotational axis of the fan.
19. The dispenser of claim 1, wherein the predetermined dimension of the opening is greater than a dimension of the wick.
20. The dispenser of claim 1, including a fan blade of the fan having a length R measured from an axis of rotation of the fan to the farthest end of the fan blade away from the axis of rotation and wherein the predetermined dimension of the opening does not exceed 1.25 R.
21. The dispenser of claim 20, wherein the predetermined dimension of the opening does not exceed 1.1 R.
22. The dispenser of claim 20, wherein the predetermined dimension of the opening does not exceed 0.9 R.
23. The dispenser of claim 20, wherein the predetermined dimension of the opening does not exceed 0.7 R.
24. The dispenser of claim 20, wherein the predetermined dimension of the opening does not exceed 0.5R.
25. The dispenser of claim 1 wherein the wick has a dimension not to exceed 1.2 of a length R of a fan blade of the fan measured from an axis of rotation to a farthest end of the fan blade away from the axis of rotation.
26. The dispenser of claim 25, wherein the dimension of the wick does not exceed R.
27. The dispenser of claim 25, wherein the dimension of the wick does not exceed 0.8R.
28. The dispenser of claim 25, wherein the dimension of the wick does not exceed 0.6R.
29. The dispenser of claim 25, wherein the dimension of the wick does not exceed 0.4R.
30. The dispenser of claim 1, wherein the predetermined dimension of the opening is positioned generally transverse to an axis of rotation of the fan.
31. The dispenser of claim 1, wherein the dispenser operates at room ambient temperature.
32. The dispenser of claim 1, wherein the guide is adapted to position the wick within a cylindrical volume centered along an axis of rotation of the fan and having a radius which extends from the axis of rotation to the farthest extension of a fan blade of the fan.
33. The dispenser of claim 1 wherein the guide comprises a projection extending from a surface of the housing and positioned spaced apart from another surface of the housing, and the opening comprises a separation between the projection and the other surface of the housing.
34. The dispenser of claim 33 wherein the projection is spaced apart from a rotational axis of the fan in a direction transverse to a direction in which the wick is received into the opening.
35. A dispenser for a volatile liquid, comprising:
a housing;
a fan mounted to the housing to generate an air stream;
a guide associated with the housing provides at least one boundary in defining an opening in which the opening has a predetermined dimension to selectively receive a wick and to position the wick in alignment with the fan to immerse the wick into an air stream when the fan is activated, wherein the guide is integral with the housing, and wherein the guide comprises opposing sidewalls defining another opening of the housing.
36. A method for assembling a dispenser for a volatile liquid, comprising the steps of:
providing a fan mounted to a housing; and
providing a guide associated with the housing in which the guide includes a projection disposed on an inside surface of the housing that at least partly defines an opening having a predetermined dimension to selectively receive a wick and align the wick to be immersed in an air stream when the fan is activated.
37. The method of claim 36 including the step of inserting a wick into the opening to be aligned with the fan.
38. The method of claim 36 in which the step of inserting includes positioning the wick in alignment with an axis of rotation of the fan.
39. The method of claim 38 in which the step of inserting includes providing the predetermined dimension to be larger than a dimension of the wick.
40. The method of claim 36 includes providing the predetermined dimension of the opening not to exceed 1.25 of the length R of a fan blade of the fan measured from an axis of rotation of the fan to a farthest end of a fan blade away from the axis of rotation of the fan.
41. The method of claim 40 in which the step of providing includes providing the predetermined dimension of the opening not to exceed 1.1 R.
42. The method of claim 40 in which the step of providing includes providing the predetermined dimension of the opening not to exceed 0.9 R.
43. The method of claim 40 in which the step of providing includes providing the predetermined dimension of the opening not to exceed 0.7R.
44. The method of claim 40 in which the step of providing includes providing the predetermined dimension of the opening not to exceed 0.5R.
45. The method of claim 36, includes the step of providing the dimension of the wick not exceed 1.2 of the length R of a fan blade of the fan measured from an axis of rotation of the fan to a farthest end of the fan blade away from the axis of rotation.
46. The method of claim 43, includes the step of providing a, dimension of the wick not to exceed R.
47. The method of claim 43, includes the step of providing a dimension of the wick not to exceed 0.8R.
48. The method of claim 43, includes the step of providing a dimension of the wick not to exceed 0.6R.
49. The method of claim 43, includes the step of providing a dimension of the wick not to exceed 0.4R.
50. The method of claim 36 in which the step of providing a guide includes positioning the wick within a cylindrical volume centered along an axis of rotation of the fan and having a radius which extends from the axis of rotation to the farthest end of a fan blade from the axis of rotation of the fan.
51. The method of claim 36 including the step of providing the predetermined dimension of the opening in an orientation generally transverse to an axis of rotation of the fan.
52. The method of claim 36 wherein the dispenser operates at room ambient temperature.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method for evaluating the presence, absence, nature or extent of breast cancer or a precancerous condition of the breast, the method comprising:
providing a biological sample obtained from a subject, the biological sample comprising glycoproteins;
contacting the biological sample with a glycan-binding molecule specific for a glycan, under conditions that permit binding of the glycan-binding molecule to a glycoprotein comprising said glycan, wherein the glycan comprises a GlcNAc \u03b2(1,6) Man branched N-linked glycan;
contacting the glycoprotein with an anti-periostin antibody; and
detecting binding of the glycan-binding molecule and the anti-periostin antibody to the glycoprotein to determine the presence, absence or amount of a cancer-specific glycoform of periostin in the biological sample, wherein said cancer-specific glycoform comprises the glycan and is indicative of breast cancer or a precancerous condition of the breast; and wherein the presence, absence or amount of the cancer-specific glycoform is indicative of the presence, absence, nature or extent of breast cancer or a precancerous condition of the breast.
2. The method of claim 1 wherein the glycan-binding molecule comprises a detectable label.
3. The method of claim 1 wherein the glycan-binding molecule is selected from the group consisting of a lectin, a glycospecific antibody, a glycospecific aptamer, a glycospecific peptide, and a glycospecific small molecule.
4. The method of claim 3 wherein the lectin comprises leukoagglutinating phytohemagglutinin (L-PHA).
5. The method of claim 1 wherein the glycan comprises a branched N-linked glycan extended with N-acetyllactosamine.
6. The method of claim 1 wherein the biological sample comprises a biological fluid.
7. The method of claim 1 wherein the biological sample comprises serum or plasma.
8. The method of claim 1 wherein the biological sample comprises tissue.
9. The method of claim 1 wherein the subject is a human.
10. A method for evaluating the presence, absence, nature or extent of breast cancer or a precancerous condition of the breast, the method comprising:
contacting a biological sample obtained from a subject, with a glycan-binding molecule specific for a glycan under conditions that permit binding of the glycan-binding molecule to a glycoprotein comprising said glycan, wherein the glycan comprises a GlcNAc \u03b2(1,6) Man branched N-linked glycan;
contacting the glycoprotein with an anti-periostin antibody; and
detecting binding of the glycan-binding molecule and the anti-periostin antibody to the glycoprotein to determine the presence of a cancer-specific glycoform of periostin in the biological sample, wherein the cancer-specific glycoform comprises the glycan and is indicative of the presence of cancer or a precancerous condition.
11. A diagnostic composition comprising a biomarker comprising a isolated cancer-specific glycoform of periostin comprising a GlcNAc \u03b2(1,6) Man branched N-linked glycan component.