Author: claimsbot

What is claimed is:

1. A process for the continuous preparation of polyisocyanates with a biuret structure comprising the steps of continuously reacting excess amounts of organic diisocyanates having exclusively aliphatically andor cycloaliphatically bound isocyanate groups with organic diamines having exclusively aliphatically andor cycloaliphatically bound primary amino groups at temperatures above 170 C. and adding acid before or during the reaction.
2. The process of claim 1 wherein the acid comprises a member selected from the group consisting of phosphoric acids, sulfonic acids and carboxylic acids.
3. The process of claim 1 wherein the acid comprises phosphoric acid dialkyl ester.
4. The process of claim 1 wherein the acid is added in amounts from 0.01 wt. % to 1.0 wt. %, based on diisocyanate used.
5. The process of claim 1 wherein the acid is added to the diisocyanate immediately before the diamine feed.
6. The process of claim 1 wherein the organic diisocyanate is hexamethylene diisocyanate (HDI) and the organic diamine is hexamethylene diamine (HAD).
7. The process of claim 1 wherein said temperature is above 200 C.
8. The process of claim 1 further comprising removing excess diisocyanate from the polyisocyanate solution by extraction or thin film distillation until a diisocyanate monomer contents of <0.5 wt. % is obtained.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. In a data processing system which includes a software application, installation files for the software application, and a script processing engine (SPE) to facilitate software updates, a method comprising:
storing, in a client system, a set of installation files for a software application and a script processing engine (SPE) which includes one or more of:
a set of scripting constructs to accept encoded binary data, process encoded binary data and update system files and properties; and
a facility to process installation properties;

the client system initiating updating of the software application, wherein the updating comprises initiating a server computer system to perform an on-the-fly comparison of a first set of files of a current program build of the software application with a second set of files of a release build of the software application at a server computer system to determine a set of file differences;
downloading a response file generated at the server computer system to the client system, the response file including code for one or more updates of a set of application system files and data, the data including a set of configuration keywords and parameters to guide a customized installation, wherein the response file includes only one or more select downloads based on the set of file differences;
the client system processing the response file by the sets of installation files;
processing the installation properties by the sets of installation files; and
updating, via a pre-determined code injection point, a set of application system files and an installation properties file, with the aid of the processed and decoded embedded data.
2. The method of claim 1, wherein the downloading the response file further comprises:
the client system automatically translating the set of file differences into a set of script code and encoded data; and
adding the set of script code and encoded data to the response file, which also includes the set of configuration keywords and parameters to guide a customized installation.
3. The method of claim 1, wherein processing the response file further comprises:
retrieving the set of configuration keywords and parameters from the response file; and
setting the installation properties within the installation file set to values which allow the SPE to access a scripted logic and encoded data, according to the set of configuration keywords and parameters from the response file.
4. The method of claim 3, wherein processing the installation properties further comprises:
passing the scripted logic to the SPE in order for the SPE to run the scripted logic, using values of the installation properties; and
decoding the encoded binary data with the aid of the scripted logic.
5. A data processing system comprising:
a processor;
a memory system;
a network connection to one or more server computer systems;
a utility executing on the processor that:
stores, in a client system, a set of installation files for a software application and a script processing engine (SPE) which includes one or more of:
a set of scripting constructs to accept encoded binary data, process encoded binary data and update system files and properties; and
a facility to process installation properties;

initiates an updating of the software application, wherein the updating comprises initiating a server computer system to perform an on the fly comparison of a first set of files of a current program build of the software application with a second set of files of a release build of the software application at a server computer system to determine a set of file differences;
downloads a response file generated at the server computer system to the client system, the response file including code for one or more updates of a set of application system files and data, the data including a set of configuration keywords and parameters to guide a customized installation, wherein the response file includes only one or more select downloads based on the set of file differences;
processes the response file by the sets of installation files;
processes the installation properties by the sets of installation files; and
updates, via a pre-determined code injection point, a set of application system files and an installation properties file, with the aid of the processed and decoded embedded data.
6. The system of claim 5, wherein the downloading the response file further comprises:
automatically translates the set of file differences into a set of script code and encoded data; and
adds the set of script code and encoded data to the response file, which also includes the set of configuration keywords and parameters to guide a customized installation.
7. The system of claim 5, wherein processing the response file further comprises:
retrieves the set of configuration keywords and parameters from the response file; and
sets the installation properties within the installation file set to values which allow the SPE to access a scripted logic and encoded data, according to the set of configuration keywords and parameters from the response file.
8. The system of claim 7, wherein processing the installation properties further comprises:
passes the scripted logic to the SPE in order for the SPE to run the scripted logic, using values of the installation properties; and
decodes the encoded binary data with the aid of the scripted logic.
9. A computer program product comprising:
a machine readable storage device; and
program code on the machine readable storage device that when executed by a data processing system performs the functions of:
storing, in a client system, a set of installation files for a software application and a script processing engine (SPE) which includes one or more of:
a set of scripting constructs to accept encoded binary data, process encoded binary data and update system files and properties;
a facility to process installation properties;

the client system initiating updating of the software application, wherein the updating further comprises initiating a server computer system to perform an on the fly comparison of a first set of files of a current program build of the software application with a second set of files of a release build of the software application at a server computer system to determine a set of file differences;
downloading a response file generated at the server computer system to the client system, the response file including code for one or more updates of a set of application system files and data, the data including a set of configuration keywords and parameters to guide a customized installation, wherein the response file includes only one or more select downloads based on the set of file differences;
the client system processing the response file by the sets of installation files;
processing the installation properties by the sets of installation files; and
updating, via a code injection point, a set of application system files and an installation properties file, with the aid of the processed and decoded embedded data.
10. The computer program product of claim 9, wherein the code for downloading the response file further comprises code for:
automatically translating the set of file differences into a set of script code and encoded data; and
adding the set of script code and encoded data to the response file, which also includes the set of configuration keywords and parameters to guide a customized installation.
11. The computer program product of claim 9, wherein the code for processing the response file further comprises code for:
retrieving the set of configuration keywords and parameters from the response file; and
setting the installation properties within the installation file set to values which allow the SPE to access a scripted logic and encoded data, according to the set of configuration keywords and parameters from the response file.
12. The computer program product of claim 11, wherein the code for processing the installation properties file further comprises code for:
passing the scripted logic to the SPE in order for the SPE to run the scripted logic, using values of the installation properties; and
decoding the encoded binary data with the aid of the scripted logic.

1. A prefilled syringe filled with a drug comprising:
a hollow cylinder having a nozzle coupled to the opening of the cylinder at a first end and configured to be fitted with an injection needle, and a guard-shaped extension proximate to the nozzle and axially projecting from a shoulder section of the cylinder;
a plunger having a plunger rod and a gasket fixedly coupled to a first end of the plunger rod, the plunger arranged to freely move backwards and forwards within the opening of the cylinder at a second end; and
a barrier package that covers the peripheral surface of the cylinder between the first end thereof proximate to the guard-shaped extension and the second end thereof proximate to the opening.
2. The prefilled syringe according to claim 1, further comprising:
a cap fitted onto an end of the nozzle; and
a shrink film that covers the entire outer peripheral surface of the cap fitted onto the nozzle and the guard-shaped extension.
3. The prefilled syringe according to claim 1, further comprising:
a cap fitted onto an end of the nozzle; and
a shrink film that covers the entire outer peripheral surface of the prefilled syringe, the shrink film also covers the barrier package, the cap fitted onto the nozzle and the plunger.
4. The prefilled syringe according to claim 3, further comprising:
a filter member that is permeable to moisture,
the plunger rod includes a disc-shaped flange with at least one air through-hole, the disc-shaped flange is coupled to a second end of the plunger rod, the filter member arranged adjacent to an outside surface of the disc-shaped flange so as to cover the air through-hole.
5. The prefilled syringe according to claim 4, wherein
the outer surface of the disc-shaped flange has an undulating surface, the undulating surface includes a recess with the air through-hole.
6. The prefilled syringe according to claim 4, wherein
the plunger rod further includes a first disc-shaped rib projecting from a central part thereof, the first disc-shaped rib has at least one air through-hole.
7. The prefilled syringe according to claim 6, wherein
the hollow cylinder further having at least one second disc-shaped rib projecting from the outer peripheral surface of the cylinder.
8. The prefilled syringe according to claim 4, further comprising:
a lid member that supports the filter member, the lid member is arranged on the outside surface of the disc-shaped flange.
9. The prefilled syringe according to claim 7, wherein
the shrink film is heat-shrunk and firmly attached to the first disc-shaped rib and the second disc-shaped rib so as to cover the entire prefilled syringe.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A leak diagnosis device comprising:
a diagnosing device for performing leak diagnosis of determining whether a leak hole is formed in a purge device, which adsorbs fuel vapor generated in a fuel tank with an adsorbent in a canister and purges the fuel vapor adsorbed by the adsorbent into an intake passage of an internal combustion engine;
a state sensing device, when the fuel vapor adsorbed by the adsorbent separates from the adsorbent and produces a mixture gas, for sensing a state of the fuel vapor in the mixture gas; and
a period calculating device for causing the state sensing device to perform the state sensing multiple times from a period in which the pressure in the purge device increases due to generation of the fuel vapor after an operation of the engine is stopped and for calculating a state stabilization period in which a change of the fuel vapor state becomes equal to or less than a reference value based on the result of the multiple times of the state sensing, wherein
the diagnosing device performs the leak diagnosis in the state stabilization period calculated by the period calculating device.
2. The leak diagnosis device as in claim 1, wherein
the state sensing device includes:
a measurement passage provided with a restrictor;
a gas flow generating device for generating a gas flow in the measurement passage;
a pressure measuring device for measuring pressure downstream of the restrictor when the gas flow generating device generates the gas flow;
a first switching device for switching between a first measurement state in which the measurement passage opens into an atmosphere such that the gas flowing through the measurement passage is an air and a second measurement state in which the measurement passage communicates with the canister such that the gas flowing through the measurement passage is the mixture gas containing the fuel vapor; and
a state calculating device for calculating the state of the fuel vapor based on first pressure measured by the pressure measuring device in the first measurement state and second pressure measured by the pressure measuring device in the second measurement state,

the diagnosing device has a second switching device for forming a third measurement state in which the mixture gas containing the fuel vapor flows from the canister to the measurement passage downstream of the restrictor not through the restrictor, and
the diagnosing device performs the leak diagnosis of the purge device based on the first pressure measured by the pressure measuring device in the first measurement state and third pressure measured by the pressure measuring device in the third measurement state.
3. The leak diagnosis device as in claim 1, wherein
the period calculating device causes the state sensing device to perform the state sensing for each elapse of a predetermined time after the operation of the engine is stopped and determines that the state stabilization period is reached if a difference between a previously sensed state and a presently sensed state is equal to or less than a predetermined value.
4. The leak diagnosis device as in claim 3, wherein
the period calculating device determines that the state stabilization period is reached if the difference between the previously sensed state and the presently sensed state is equal to or less than the predetermined value certain times successively.
5. The leak diagnosis device as in claim 1, wherein
the period calculating device estimates the state stabilization period, in which the change of the fuel vapor state is equal to or less than the reference value, based on magnitude of the state change occurring over two or more times of the state sensing.
6. The leak diagnosis device as in claim 1, further comprising:
an ambient temperature measuring device for measuring ambient temperature, wherein
the diagnosing device sustains the leak diagnosis if the state sensing of the fuel vapor state performed after the operation of the engine is stopped detects a state in which a margin of an adsorbing ability of the adsorbent is short and the ambient temperature measured by the ambient temperature measuring device is equal to or higher than certain temperature.
7. A leak diagnosis method of performing leak diagnosis of determining whether a leak hole is formed in a purge device, which adsorbs fuel vapor with an adsorbent, the leak diagnosis method comprising the steps of:
sensing a state of the fuel vapor in a mixture gas produced by the fuel vapor separating from the adsorbent; and
calculating a state stabilization period in which a change of the state of the fuel vapor is equal to or less than a reference value based on the result of multiple times of the sensing, wherein
the leak diagnosis is performed in the state stabilization period.