Author: claimsbot

1. A method of inhibiting cadherin-11 activity in a subject, comprising:
administering to the subject an effective amount of a compound of the following formula:
or a pharmaceutically acceptable salt thereof, wherein:
R1 and R2 are hydrogen;
R3, R4, R5, R6, R7, R8, R9, R11 and R12 are each independently selected from hydrogen, halogen, hydroxy, substituted or unsubstituted alkoxy, substituted or unsubstituted amido, substituted or unsubstituted amino, substituted carbonyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, unsubstituted heteroalkyl, substituted or unsubstituted heteroalkenyl, substituted or unsubstituted heteroalkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted cycloalkynyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted heterocycloalkenyl, substituted or unsubstituted heterocycloalkynyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl;
R10 is selected from halogen, hydroxy, substituted alkoxy, substituted or unsubstituted amido, substituted or unsubstituted amino, substituted carbonyl, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, unsubstituted heteroalkyl, substituted or unsubstituted heteroalkenyl, substituted or unsubstituted heteroalkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted cycloalkynyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted heterocycloalkenyl, substituted or unsubstituted heterocycloalkynyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; and
X1 and X2 are each N,
wherein when one or more of R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are substituted, the substituent is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, heteroalkyl, heteroalkenyl, heteroalkynyl, heteroaryl, cycloalkyl, cycloalkenyl, cycloalkynyl, heterocycloalkyl, heterocycloalkenyl, and heterocycloalkynyl.
2. The method of claim 1, wherein the subject has a cadherin-11 related disease.
3. The method of claim 2, wherein the cadherin-11 related disease is cancer.
4. The method of claim 3, wherein the cancer is breast cancer, prostate cancer, glioma, glioblastoma, myeloma, leukemia, a poor prognosis or invasive cancer, a basal-like cancer, a mesenchymal-like cancer, or metastatic cancer.
5. The method of claim 2, wherein the cadherin-11 related disease is rheumatoid arthritis.
6. The method of claim 1, wherein the method further comprises administering a second therapeutic agent to the subject.
7. The method of claim 6, wherein the second therapeutic agent is a chemotherapeutic agent or an anti-inflammatory agent.
8. The method of claim 1, wherein X1 and X2 are N; R1, R2, R3, R4, R5, R6, R7, R8, R9, R11, and R12 are each H; and R10 is OH.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. An illumination device comprising:
a light source including a substantially planar light-emitting surface,
an optical taper including a light receiving end and a second end, the light receiving end having a smaller surface area than the second end and the light receiving end matching an area of the substantially planar light-emitting surface; and
a light post taper;
wherein the light receiving end of the optical taper is disposed proximate to the substantially planar light-emitting surface to optically couple the optical taper and the substantially planar light-emitting surface, and the second end of the optical taper is proximate to the light post taper.
2. The illumination device of claim 1, wherein the substantially planar light-emitting surface comprises an emitting surface of a light-emitting diode chip.
3. The illumination device of claim 1, wherein the substantially planar light-emitting surface comprises a transparent substantially planar window disposed over an emitting surface of a light-emitting diode chip.
4. The illumination device of claim 1, wherein the light receiving end is in direct contact with the substantially planar light-emitting surface of the light source.
5. The illumination device of claim 1, wherein the second end is in direct contact with the substantially planar light-emitting surface of the light source.
6. The illumination device of claim 1, wherein an adhesive or an index matching material is disposed between the optical taper and the substantially planar light-emitting surface.
7. The illumination device of claim 1, wherein a gas is disposed between the optical taper and the substantially planar light-emitting surface.
8. The illumination device of claim 1, wherein the optical taper comprises a glass optical taper.
9. The illumination device of claim 1, wherein the optical taper comprises a plastic optical taper.
10. The illumination device of claim 1, wherein the light receiving end of the optical taper is proximate to the substantially planar light-emitting surface of the light source and the second end of the optical taper is proximate to a light guide.
11. The illumination device of claim 1, wherein a light receiving end of the light post taper is proximate to the optical taper and a light transmitting end of the light post taper is attached to a light guide.
12. The illumination device of claim 1 disposed within an endoscope.
13. The illumination device of claim 1 disposed within a lamp.
14. The illumination device of claim 1, further comprising a substance that emits light when the light source is activated, the substance being positioned between the substantially planar light-emitting surface and the optical taper.

1. A method comprising:
receiving, by an integrated circuit, input data of a Galois field GF(2.sup.k);
mapping the input data to a composite Galois field GF(2.sup.nm), wherein k=nm;
inputting the mapped input data to an Advanced Encryption Standard round function, wherein the Advanced Encryption Standard round function comprises bypassing an affine transformation block of a datapath when the input data is to be decrypted;
performing, by the integrated circuit, two or more iterations of the Advanced Encryption Standard round function in the composite Galois field GF(2.sup.nm);
receiving output data of a last of the two or more iterations of the Advanced Encryption Standard round function; and
mapping the output data to the Galois field GF(2.sup.k).
2. The method of claim 1, wherein the Advanced Encryption Standard round function comprises:
performing a SubstituteByte transformation in the composite Galois field GF(2.sup.nm);
performing a ShiftRow transformation in the composite Galois field GF(2.sup.nm);
performing a MixColumns transformation in the composite Galois field GF(2.sup.nm); and
performing an AddRoundKey operation in the composite Galois field GF(2.sup.nm).
3. The method of claim 1, wherein the Advanced Encryption Standard round function comprises:
computing X.sup.\u22125*X.sup.4 in the composite Galois field GF(2.sup.nm), wherein X is the input data.
4. The method of claim 1, wherein the Advanced Encryption Standard round function comprises:
bypassing an inverse-affine transformation block of the datapath when the input data is to be encrypted.
5. The method of claim 1, wherein bypassing the affine transformation block comprises:
activating a bypass path of an integrated mux-XOR circuit.
6. A circuit comprising:
a first circuit to receive input data of a Galois field GF(2.sup.k) and to map the input data to a composite Galois field GF(2.sup.nm), wherein k=nm;
an encrypt-decrypt circuit to receive the mapped input data and to perform two or more iterations of an Advanced Encryption Standard round function in the composite Galois field GF(2.sup.nm), wherein the encrypt-decrypt circuit includes a datapath comprising an affine transformation block which is bypassed when the input data is to be decrypted; and
a second circuit to receive output data of a last of the two or more iterations of the Advanced Encryption Standard round function, and to map the output data to the Galois field GF(2.sup.k).
7. The circuit of claim 6, wherein the encrypt-decrypt circuit comprises:
a SubstituteByte circuit to perform a SubstituteByte transformation in the composite Galois field GF(2.sup.nm);
a ShiftRow circuit to perform a ShiftRow transformation in the composite Galois field GF(2.sup.nm);
a MixColumns circuit to perform a MixColumns transformation in the composite Galois field GF(2.sup.nm); and
an AddRoundKey circuit to perform an AddRoundKey operation in the composite Galois field GF(2.sup.nm).
8. The circuit of claim 6, wherein the SubstituteByte circuit comprises:
a circuit to compute X.sup.\u22125*X.sup.4 in the composite Galois field GF(2.sup.nm), wherein X is the input data.
9. The circuit of claim 6, wherein the datapath of the encrypt-decrypt circuit further comprises:
an inverse-affine transformation block,
which is bypassed when the input data is to be encrypted.
10. The circuit of claim 6, wherein the affine transformation block comprises:
an integrated mux-XOR circuit to bypass the affine transformation block.
11. The circuit of claim 7, wherein the ShiftRow circuit comprises:
a datapath comprising a ShiftRow block and an InverseShiftRow block.
12. The circuit of claim 7, wherein the MixColumns circuit comprises:
a datapath comprising a MixColumns block and an InverseMixColumns block.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. An activation system for establishing a voice communication through a radio system in a vehicle, the radio system having an audio controller and a device interface, the activation system comprising:
a switch to send a first activation signal and a second activation signal when a user desires to accept an incoming voice communication, the first activation signal received by the audio controller of the radio system;
a wireless communication device having a controller, a cellular transceiver, a radio interface, and a means for detecting the second activation signal from the switch, the cellular transceiver for receiving downlink audio of the voice communication; and
a communication cord interconnecting the device interface of the radio system to the radio interface of the wireless communication device;

wherein the switch is remote from the wireless communication device and the radio system, the controller in the wireless communication device, in response to detecting the second activation signal from the switch, sends the downlinik audio of the voice communication received by the cellular transceiver to the radio interface for sending to the radio system over the communication cord.
2. An activation system in claim 1 wherein the audio controller in the radio system, in response to receiving the first activation signal from the switch, is capable of sending the downlinik audio of the voice communication from the device interface to at least one speaker in the radio system.
3. An activation system in claim 2 wherein the radio system further includes a microphone that receives uplink audio of the voice communication, the audio controller, in response to receiving the first activation signal from the switch, is further capable of sending the uplink audio of the voice communication to the device interface for sending to the wireless communication device over the communication cord.
4. An activation system in claim 3 wherein the cellular transceiver of the wireless communication device further is capable of transmitting uplink audio of the voice communication, the controller in the wireless communication device, in response to detecting the second activation signal from the radio system, further configures the wireless communication device to receive the uplink audio of the voice communication from the radio interface for transmittal by the cellular transceiver.
5. An activation system in claim 1 wherein the device interface of the radio system and the radio interface of the wireless communication device are 2.5 mm jack interfaces.
6. An activation system in claim 1 wherein the means for detecting the second activation signal in the wireless communication device includes sensing a temporary grounding of a line in the communication cord.
7. An activation system for establishing a voice communication through a radio system in a vehicle, the activation system comprising:
a remote activation device having a switch and a transmitter, the transmitter responsive to the switch and capable of transmitting a first activation signal and a second activation signal, the remote activation device remote from the radio system and capable of transmitting the first activation signal to the radio system; and
a wireless communication device having a controller, a radio transceiver, a cellular transceiver, and a radio interface, the controller capable of detecting the second activation signal from the remote activation device through the radio transceiver, the cellular transceiver for receiving downlink audio of the voice communication;
wherein the controller in the wireless communication device, in response to detecting the second activation signal from the remote activation device, sends the downlink audio of the voice communication received by the cellular transceiver to the radio interface for transmittal to the radio system in the vehicle.
8. The activation system in claim 7, wherein the controller can detect the presence of the radio system when a connector is connected to the radio interface.
9. The activation system in claim 7, wherein the remote activation device is incorporated into a portable electronic device for the vehicle.
10. The activation system in claim 7, wherein the radio system has a device interface and an audio controller, the device interface capable of receiving the downlink audio of the voice communication, the audio controller capable of detecting the first activation signal and routing the downlink audio of the voice communication from the device interface to at least one speaker in the vehicle in response to detecting the first activation signal.
11. The activation system in claim 7, wherein the cellular transceiver is further capable of transmitting uplink audio of the voice communication, the controller in the wireless communication device, in response to detecting the second activation signal from the remote activation device, routes the uplink audio of the voice communication from an external microphone to the cellular transceiver for transmission.
12. A remote activation device for establishing a voice communication for a wireless communication device through a radio system, the remote activation device remote from the wireless communication device and the radio system, the wireless communication device having a controller, a radio transceiver, a cellular transceiver, and a radio interface, the remote activation device comprising:
a transmitter for transmitting a first signal to the controller in the wireless communication device through the radio transceiver and for transmitting a second signal to the radio system through the radio transceiver; and
a switch for activating the transmitter;

wherein the first signal is capable of causing the wireless communication device to accept an incoming voice communication and route the voice communication to the radio interface for transmittal to the radio system in the vehicle
wherein the second signal is capable of causing the radio system to switch an audio input to receive downlink audio of the voice communication from the wireless communication device.
13. The remote activation device in claim 12, wherein the remote activation device is incorporated into a portable electronic device for the vehicle.
14. The remote activation device in claim 12, wherein the radio system has a device interface and an audio controller, the device interface capable of receiving downlink audio of the voice communication, the audio controller capable of detecting the second signal and routing the downlink audio of the voice communication from the device interface to at least one speaker in the vehicle in response to detecting the second signal.
15. A remote activation device for establishing a voice communication for a wireless communication device through a radio system, the remote activation device remote from the wireless communication device and the radio system, the wireless communication device having a radio interface that is interconnected to a device interface in the radio system, the remote activation device comprising:
a switch; and
a transmitter responsive to the switch for transmitting a first signal and a second signal;
wherein the first signal indicates to the wireless communication device to accept an incoming voice communication, and the second signal indicates to the radio system to switch an audio input to receive downlink audio of the voice communication sent over the radio interface and device interface by the wireless communication device.
16. The remote activation device in claim 15, wherein the wireless communication device has a controller, a cellular transceiver, and a radio transceiver, the controller capable of detecting the first signal from the remote activation device through the radio transceiver.
17. The remote activation device in claim 16, wherein the controller in the wireless communication device, in response to detecting the first signal from the remote activation device, sends downlink audio of the voice communication received by the cellular transceiver over a communication cord for transmittal to the radio system, the communication cord connected between the radio interface and the device interface.
18. The remote activation device in claim 15, wherein the radio system has an audio controller and a radio transceiver, the audio controller capable of detecting the second signal from the remote activation device through the radio transceiver.
19. The remote activation device in claim 18, wherein the audio controller in the radio system, in response to detecting the second signal from the remote activation device, switches the audio input to receive the downlink audio from the voice communication sent over a communication cord by the wireless communication device, the communication cord connected between the radio interface and the device interface.
20. A method to activate downlink audio of a voice communication through a radio system in a vehicle, the method comprising the steps of:
notifying the user of a pending incoming voice communication to a wireless communication device;
transmitting a first signal from a remote activation device to the wireless communication device if the pending incoming voice communication is accepted;
transmitting a second signal from the remote activation device to the radio system if the pending incoming voice communication is accepted;

detecting the first signal in the wireless communication device from the remote activation device;
detecting the second signal in the radio system from the remote activation device; sending the downlink audio of the voice communication from the wireless communication device to the radio system through a communication cord after detecting the first signal from the remote activation device; and
switching an audio input to receive the downlink audio of the voice communication from the wireless communication device in response to detecting the second signal.