Author: claimsbot

1. An avian pancreatic polypeptide (aPP) modified by substitution of at least one amino acid residue, wherein said at least one residue is located within a type II polyproline (PPII) helix of the polypeptide when the polypeptide is in a tertiary form.
2. The modified polypeptide of claim 1, wherein at least two or three amino acid residues on the PPII helix are substituted.
3. The modified polypeptide of claim 1, further modified by substitution of at least one amino acid residue in the linker region between the PPII helix and the alpha helix domain of the polypeptide.
4. The modified polypeptide of claim 3, wherein at least two amino acid residues on the linker region are substituted.
5. The modified polypeptide of claim 1, wherein said at least one substituted residue of the PPII helix is selected from a site on a first protein through which the first protein interacts with a second protein.
6. The modified polypeptide of claim 5, wherein the first protein is selected from the group consisting of: zyxin, vinculin, and the ActA protein of Listeria monocytogenes.
7. The modified polypeptide of claim 5, wherein the second protein is selected from the group consisting of: Drosophila Enabled (Ena), mammalian Mena, vasodilator stimulated phosphoprotein (VASP), EnabledVASP-like protein (Evl), and Wiskott-Aldrich syndrome protein (WASP).
8. The modified polypeptide of claim 5, wherein the site is a protein binding site.
9. The modified polypeptide of claim 1, having an amino acid sequence selected from any of SEQ ID NOs: 1-5.
10. The modified polypeptide of claim 1, wherein the modified polypeptide binds to a protein selected from the group consisting of: Drosophila Enabled (Ena), mammalian Mena, vasodilator stimulated phosphoprotein (VASP), EnabledVASP-like protein (Evl), and Wiskott-Aldrich syndrome protein (WASP).
11. The modified polypeptide of claim 10, wherein the modified polypeptide preferentially binds to one protein selected from the group consisting of: Drosophila Enabled (Ena), mammalian Mena, vasodilator stimulated phosphoprotein (VASP), EnabledVASP-like protein (Evl), and Wiskott-Aldrich syndrome protein (WASP), but doe not bind to the other proteins of the group.
12. The modified polypeptide of claim 1, wherein the modified polypeptide inhibits interaction between the known protein and the second protein.
13-17. (canceled)
18. An isolated polypeptide selected from the group consisting of:
(a) an isolated polypeptide comprising any of the amino acid sequences as set forth in SEQ ID NOs: 1-5;
(b) an isolated polypeptide comprising a fragment of at least twelve contiguous amino acids of any of SEQ ID NOs: 1-5;
(c) an isolated polypeptide comprising one or more amino acid substitutions in any of the amino acid sequences as set forth in SEQ ID NOs: 1-5; and
(d) an isolated polypeptide at least 95 percent identical to any of SEQ ID NOs: 1-5.
19-20. (canceled)
21. A method of identifying an avian pancreatic polypeptide (aPP) miniature protein that modulates the interaction between a known protein and a second protein, comprising a step of isolating at least one recombinant phage clone from a phage display library that displays a protein scaffold that modulates the association between a known protein and a second protein, the phage display library comprising a plurality of recombinant phase that express a protein scaffold modified by substitution of at least one amino acid residue, said at least one residue being exposed on a type II polyproline (PPII) helix of the polypeptide when the polypeptide is in a tertiary form.
22-38. (canceled)

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A light filter, comprising:
a pair of opposed substrates having a gap therebetween;
an electrode disposed on each of said substrates, wherein each pairing of said electrode and said substrate has associated therewith reflective properties;
a polymer film disposed on and chemically bonded to one of said electrodes, wherein application of a voltage across said electrodes causes a corresponding uniform change in a thickness of said polymer film.
2. The light filter according to claim 1, further comprising:
a reflective coating disposed on one of each said electrode and said substrate pairing.
3. The light filter according to claim 2, wherein said reflective coatings have a reflectance greater than 75%.
4. The light filter according to claim 3, wherein said reflectance is greater than 90%.
5. The light filter according to claim 4, wherein said reflectance is greater than 99%.
6. The light filter according to claim 1, further comprising:
a plurality of spacers disposed between said substrates to maintain said gap, wherein a change in said thickness of said polymer film results in a variation of an optical path length of the filter.
7. The light filter according to claim 6, wherein application of said voltage causes said polymer film to change from an unactivated condition to either a compressed condition or an extended condition.
8. The light filter according to claim 7, wherein said extended condition of said polymer film is less than said gap.
9. The light filter according to claim 7, wherein said thickness of said polymer film in said unactivated condition is less than five microns.
10. The light filter according to claim 7, wherein said thickness of said polymer film in said unactivated condition is less than one micron.
11. The light filter according to claim 1, wherein said polymer film is a soft solid having a tangent delta of less than 0.15 and modulus of less than about 40,000 pascals.
12. The light filter according to claim 1, wherein said polymer film is a soft solid having a tangent delta of less than 0.05.
13. The light filter according to claim 1, further comprising:
a controller connected to said electrodes to control application of said voltage to said polymer film.
14. The light filter according to claim 1, wherein said polymer film comprises a monolayer.
15. The light filter according to claim 14, wherein said polymer film comprises a polar group that causes said polymer film to be responsive to application of said voltage.
16. The light filter according to claim 1, wherein said polymer film comprises a polymer selected from the group consisting of acrylic, polyurethane, saturated rubber, polysiloxane, and copolymers and terpolymers thereof, and wherein the polymer is modified to be responsive to an electric field.
17. The light filter according to claim 1, wherein said polymer comprises polysiloxane.
18. The light filter according to claim 17, wherein said polymer comprises polymer having a polydispersity of less than about 1.5.
19. The light filter according to claim 17, wherein said polymer comprises polymer molecules that contains from zero up to about 1.5 ionic groups per polymer molecule.
20. The light filter according to claim 19, wherein the polymer molecules contain one or more ionic groups selected from the group consisting of sulfonate, sulfate, phosphonate, phosphate, polyphosphate, carboxylate, acrylate, germinate, silicate, and ammonium groups.
21. The light filter according to claim 17, wherein the polysiloxane is grafted to one or more low molecular weight polymers selected from the group consisting of polyacrylates, polyethers, polystyrenes, polysulphones, polyureas, polyamides, polyimides, polyamide-imides, polyesters, polycarbonates, and epoxy resins.
22. The light filter according to claim 17, wherein the polysiloxane includes one or more non-reactive groups selected from the group consisting of phenyl groups, fluoroalkyl groups, alkyl groups containing 2 or more carbon atoms, and cyano groups.
23. The light filter according to claim 17, wherein the polysiloxane is bonded chemically or physically to nano particles, wherein the nano particles are selected from the group consisting of nanoclay, activated calcium carbonate, silica, POSS, and surface modified silica.
24. The light filter according to claim 17, wherein the polysiloxane is bonded at multiple sites to phenyl silanes selected from the group consisting of triphenyl silane and triphenyl vinyl silane.
25. The light filter according to claim 17, wherein said polymer comprises polymer molecules contain one or more non-ionic polar functional groups with unsymmetrical charge distribution.
26. The light filter according to claim 25, wherein said non-ionic polar functional groups are selected from the group consisting of polypropylene oxide, polyphenylene oxide, and polyvinyl ethers.
27. The light filter according to claim 17, wherein the polysiloxane is linear polydimethyl siloxane.
28. The light filter according to claim 27, wherein said linear polydimethyl siloxane has two methyl groups bonded to each silicon atom.
29. The light filter according to claim 28, wherein at least one of said methyl groups is replaced by another substituent on a low percentage of silicon atoms.
30. The light filter according to claim 29, wherein said substituent is selected from the unreactive group consisting of phenyl groups, fluoroalkyl groups, alkyl groups containing two or more carbon atoms and cyano groups.
31. The light filter according to claim 1, wherein said polymer comprises a polymer having cationic functionality.
32. The light filter according to claim 1, wherein said polymer comprises a polymer having anionic functionality.
33. The light filter according to claim 1, further comprising:
a second polymer film disposed on and chemically bonded to the other of said electrodes, wherein application of said voltage across said electrodes causes corresponding changes in thickness of said polymer films, and wherein said polymer films are sized to not contact the other upon application of said voltage.
34. The light filter according to claim 1, further comprising:
an anti-reflective coating disposed on a side of one of said substrates outside of said gap, said substrate facing a light source.
35. The light filter according to claim 34, further comprising:
an absorption layer disposed on a side of the other substrates outside of said gap and away from said light source.
36. The light filter according to claim 1, wherein said polymer film is patterned coated on said electrode.
37. The light filter according to claim 1, wherein said polymer film and said electrodes are patterned to form a matrix of filters.
38. The light filter according to claim 1, wherein said electrode is a reflective material.
39. The light filter according to claim 38, wherein said reflective material is selected from the group consisting of gold, silver, platinum, aluminum and alloys thereof.
40. The light filter according to claim 39, further comprising a dielectric material coated on said reflective material.
41. The light filter according to claim 1, wherein said uniform change in said thickness of said polymer film results in a change in an optical path length between said pair of opposed substrates.

What is claimed is:

1. A method of marking data objects on an electronic device to be transferred by the electronic device, the method comprising the steps of:
a) presenting a data object on a user interface of the electronic device;
b) applying a set of criteria to the data object to determine if the data object is capable of being transferred; and
c) providing an indicator if the data object is capable of being transferred by the electronic device.
2. The method of claim 1, wherein presenting a data object on the user interface of the electronic device comprises displaying the data object on a display of the electronic device.
3. The method of claim 1, wherein if the data object is capable of being transferred, further comprising the steps of:
d) allowing the data object to be selected for transfer; and
e) transferring the data object.
4. The method of claim 3, wherein the step of allowing the data object to be selected for transfer further comprises adding the data object to a modifiable list of data objects selected for transfer.
5. The method of claim 1, wherein the applying a set of criteria step comprises the step of retrieving one or more attributes of the data object and determining if the attributes exceed predetermined transfer limitations.
6. The method of claim 5, wherein the predetermined transfer limitations comprise file size limitations, confidentiality limitations, and file type limitations.
7. The method of claim 1, wherein the step of providing an indicator comprises presenting an icon on the user interface of the electronic device.
8. The method of claim 1, wherein the step of providing an indicator comprises sounding an auditory alert on the electronic device.
9. The method of claim 1, wherein the step of providing an indicator comprises illuminating a dedicated button on the electronic device.
10. A method of marking data objects on an electronic device to be transferred by the electronic device, the method comprising the steps of:
a) presenting a data object on a user interface of the electronic device;
b) applying a set of criteria to the data object to determine if the data object is capable of being transferred; and
c) providing an indicator if the data object is incapable of being transferred by the electronic device.
11. The method of claim 10, wherein presenting a data object on the user interface of the electronic device comprises displaying the data object on a display of the electronic device.
12. The method of claim 10, wherein if the data object is capable of being transferred, further comprising the steps of:
d) allowing the data object to be selected for transfer; and
e) transferring the data object.
13. The method of claim 12, wherein the step of allowing the data object to be selected for transfer further comprises adding the data object to a modifiable list of data objects selected for transfer.
14. The method of claim 10, wherein the applying a set of criteria step comprises the step of retrieving one or more attributes of the data object and determining if the attributes exceed predetermined transfer limitations.
15. The method of claim 14, wherein the predetermined transfer limitations comprise file size limitations, confidentiality limitations, and file type limitations.
16. The method of claim 10, wherein the step of providing an indicator comprises presenting an icon on the user interface of the electronic device.
17. The method of claim 10, wherein the step of providing an indicator comprises sounding an auditory alert on the electronic device.
18. The method of claim 10, wherein the step of providing an indicator comprises illuminating a dedicated button on the electronic device.
19. A method of marking a plurality of data objects on an electronic device for transfer, comprising the steps of:
a) presenting a first data object;
b) applying a set of criteria to the data object to determine if the first data object is capable of transfer;
c) providing an indicator if the first data object is capable of being transferred by the electronic device;
d) allowing user to select the first data object for transfer;
e) adding the selected data object to a list of data objects for transfer;
f) presenting a next data object; and
g) repeating steps b) through e) with said next data object.
20. The method of claim 19, wherein list of data objects selected for transfer may be edited before transfer by the electronic device.
21. The method of claim 19, wherein the applying a set of criteria step comprises the step of retrieving the attributes of said first data object and determining if the attributes exceed predetermined transfer limitations.
22. The method of claim 21, wherein the predetermined transfer limitations comprise file size limitations and file type limitations.
23. The method of claim 19, wherein indicating on the user interface if the first data object is capable of transfer by the electronic device step comprises presenting an icon on the user interface of the electronic device.
24. The method of claim 19, wherein the providing an indicator step comprises sounding an auditory alert on the electronic device.
25. The method of claim 19, wherein the providing an indicator step comprises illuminating a dedicated button on the electronic device.
26. An apparatus capable of transferring one or more data objects, the apparatus comprising:
a) a memory device for containing a program module and at least one data object;
b) a user interface; and
c) a processing unit coupled to the memory device and the user interface, the processing unit being operative in response to the instructions of the program module to:
i) present a data object on a user interface of the electronic device;
ii) apply a set of criteria to the data object to determine if the data object is capable of being transmitted; and
iii) provide an indicator if the data object is capable of being transmitted.
27. The apparatus of claim 26, wherein if the processing unit determines that a data object is capable of being transmitted, further being operative in response to the instructions of the program module to:
d) allow the data object to be selected for transmission over a communications medium; and
e) transmit the data object.
28. The apparatus of claim 26, wherein the apparatus is a cellular telephone.
29. The apparatus of claim 26, wherein the apparatus is a computer with a modem.
30. The apparatus of claim 26, wherein the apparatus is a hand held computer.
31. The apparatus of claim 26, wherein the apparatus is a telephone.
32. The apparatus of claim 26, wherein the communications medium is a wireless medium.
33. The apparatus of claim 26, wherein the communications medium is a data channel of a cellular transmission medium.
34. The apparatus of claim 26, wherein the communications medium is an optical medium.
35. The apparatus of claim 26, wherein the communications medium is a wired medium.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A method comprising
causing an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature, and
at least sometimes during the non-heating state, adding heat to the air handler to heat air and delivering the heated air to the space during timed periods.
2. The method of claim 1 in which heating the air includes providing heat to a heat exchanger.
3. The method of claim 2 in which providing heat to a heat exchanger includes providing hot water to the heat exchanger.
4. The method of claim 3 in which providing hot water includes providing hot water from a domestic water heater.
5. The method of claim 4 also including interrupting the providing of the hot water based on a call for domestic hot water from the domestic water heater.
6. The method of claim 2 in which providing heat to a heat exchanger includes providing the heat in pulses.
7. The method of claim 6 in which the pulses include priming pulses that precede times when a central fan is turned on.
8. The method of claim 1 in which, during the non-heating state, the delivery of heated air is insufficient to raise the temperature of the space to meet the set temperature.
9. The method of claim 1 in which, heated air is not delivered to the space for a period at the beginning of the non-heating state.
10. The method of claim 1 in which, during the heating state, a central fan forces heated air into the space to cause the temperature in the space to become sufficient relative to the set temperature.
11. The method of claim 1 in which an actual temperature being insufficient relative to the set temperature comprises the actual temperature being essentially lower than the set temperature.
12. The method of claim 1 in which an actual temperature being sufficient relative to the set temperature comprises the actual temperature being essentially higher than the set temperature.
13. The method of claim 1 in which the heated air is delivered by a fan.
14. The method of claim 1 in which the air that is to be heated is drawn from outside the space.
15. The method of claim 1 also including adding heat in pulses that precede times when a central fan is turned on.
16. The method of claim 1 in which adding heat comprises adding heat in pulses.
17. A method comprising
causing an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature, and
at least sometimes during the non-heating state, heating the air to be delivered to the space by providing domestic hot water in pulses to a heat exchanger and delivering the heated air to the space, the delivery of heated air being insufficient to raise the temperature of the space to meet the set temperature.
18. Apparatus comprising:
ports to communicate heating signals to and from sensors and heating equipment,
a processor to control the heating equipment to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature, and
at least sometimes during the non-heating state, adding heat to the air handler to heat air and delivering the heated air to the space during timed periods.
19. The apparatus of claim 18 also including storage to hold data and instructions for use by the processor.
20. The apparatus of claim 18 also including a user interface.
21. The apparatus of claim 18 in which the processor also controls the heating equipment to heat the air to be delivered to the space.
22. The apparatus of claim 18 in which the processor also interrupt the interrupts a providing of domestic hot water to the heating equipment based on a call for domestic hot water from a domestic water heater.
23. The apparatus of claim 18 in which the processor also causes the added heat in pulses to be provided.
24. The apparatus of claim 23 in which the pulses include priming pulses that precede times when a central fan is turned on.
25. The apparatus of claim 18 in which, during the non-heating state, the delivery of heated air is insufficient to raise the temperature of the space to meet the set temperature.
26. The apparatus of claim 18 in which the processor also controls the heating equipment so that heated air is not delivered to the space for a period at the beginning of the non-heating state.
27. The apparatus of claim 18 in which the processor also controls the heating equipment so that, during the heating state, a central fan forces heated air into the space to cause the temperature in the space to become sufficient relative to the set temperature.
28. A medium bearing instructions to enable a machine to:
cause an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature, and
at least sometimes during the non-heating state, add heat to the air handler to heat air and deliver the heated air to the space during timed periods.
29. A method comprising
causing an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature,
at least sometimes during the non-heating state, adding heat to the air handler to heat air using hot water from a domestic water heater and delivering the heated air to the space, and
interrupting the adding of heat using hot water based on a call for domestic hot water from the domestic water heater.
30. A method comprising
causing an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature, and
at least sometimes during the non-heating state, adding heat in pulses to the air handler to heat air and delivering the heated air to the space.
31. A method comprising
causing an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature,
at least sometimes during the non-heating state, adding heat to the air handler to heat air and delivering the heated air to the space, and
adding heat to the air handler in pulses that precede times when a central fan is turned on.
32. A method comprising
causing an air handler to operate alternately in a heating state and a non-heating state based on a sensed temperature in a space being heated and on a set temperature,
at least sometimes during the non-heating state, adding heat to the air handler to heat air using hot water from a domestic water heater and delivering the heated air to the space,
the heated air not being delivered to the space for a period at the beginning of the non-heating state.