I claim:
1. A pad assembly, receivable within a cup, for removable engagement with the tonehole rim of a musical instrument comprising:
a compliant disc shaped cushion disposed in said cup;
a film layer adjacent to said cushion for engaging said tonehole;
said film having a hard coating.
2. The assembly of claim 1 wherein said film has a metallic coating.
3. The assembly of claim 1 wherein said film has a coating of glass fibers.
4. The assembly of claim 1 wherein said film has a crystalline coating.
5. The assembly of claim 1 wherein said film has a ceramic coating.
6. The assembly of claim 1 wherein said film has a coating of carbon fibers.
7. The assembly of claim 1 wherein said film has a coating of dry lubricant.
8. The assembly of claim 1 wherein said film is impregnated with metallic particles.
9. The assembly of claim 1 wherein said film is impregnated with glass fibers.
10. The assembly of claim 1 wherein said film is impregnated with crystals
11. The assembly of claim 1 wherein said film is impregnated with ceramic particles.
12. The assembly of claim 1 wherein said film is impregnated with carbon fibers.
13. The assembly of claim 1 wherein said film is impregnated with a dry lubricant.
14. A method for bonding a hard layer of material to the tonehole engaging pad surface of a musical wind instrument, comprising the steps of:
coating a layer of film with an adhesive;
applying a layer of hard material to the adhesive so that it bonds to said film;
positioning the combination of said film and said hard material so that they cover the cushion of said pad on the side of said cushion that engages with the tonehole of said instrument.
15. The method of claim 14 wherein said hard material is mainly comprised of metal.
16. The method of claim 14 wherein said hard material is mainly comprised of gold.
17. A pad assembly, receivable within a cup, for removable engagement with the tonehole rim of a musical instrument comprising:
a rigid disc for insertion into said cup, said disc having a first surface adjacent to said cup, an opposite second surface adjacent to a cushion, and a circumferential edge between said first and second surfaces;
a film layer in contact with said cushion for sealing engagement with said tonehole rim;
said disc having an outer peripheral collar for insertion into said cup;
said outer peripheral collar being juxtaposed laterally to the outside of said edge and said film;
18. The assembly of claim 17 wherein said outer peripheral collar is a clamping means for securing said film between said edge and said outer peripheral collar.
19. A pad assembly, receivable within a cup, for removable engagement with the tonehole rim of a musical instrument comprising:
a rigid disc for insertion into said cup, said disc having a back surface adjacent to said cup, an opposite front surface adjacent to a cushion, and a circumferential edge between said front and back surfaces;
a film layer in contact with said cushion for sealing engagement with said tonehole rim;
said disc having first and second coaxial collars for insertion into said cup;
said first collar being an outer peripheral collar and said second collar being an inner collar;
said outer peripheral collar being juxtaposed laterally to the outside of said edge and said film;
20. The assembly of claim 19 wherein said outer peripheral collar is a clamping means for securing said film between said edge and said outer peripheral collar.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A drug delivery device comprising:
a plurality of microneedles arranged on a substrate, each microneedle having a base and a tip;
wherein the tip of one or more of the microneedles has a first optical response when probed with a selected incident light spectrum;
wherein the base of the microneedle has a second optical response when probed with the selected incident light spectrum, the second optical response differing from the first optical response;
an active agent formulation covering at least a portion of the tip of one or more of the microneedles; and
wherein the active agent formulation modulates the first optical response of the microneedles when probed with the selected incident light spectrum.
2. A drug delivery device as claimed in claim 1 wherein the first optical response is selected from the group consisting of absorbance, reflection, scattering, fluorescence, image analysis, and phosphorescence.
3. A drug delivery device as claimed in claim 1 wherein the first optical response is fluorescence.
4. A drug delivery device as claimed in claim 1 wherein the first optical response is absorbance.
5. A drug delivery device as claimed in claim 1 wherein the incident light spectrum comprises visible wavelengths.
6. A drug delivery device as claimed in claim 1 wherein the incident light spectrum comprises ultraviolet wavelengths.
7. A drug delivery device as claimed in claim 1 wherein the active agent formulation prevents a portion of the incident light spectrum from reaching one or more of the microneedles.