1. A purified nucleic acid comprising nucleotide sequence SEQ ID NOS: 1 or 5, wherein said sequences are capable of being transcribed into a myofibrillogenesis-inducing RNA (MIR) molecule.
2. The purified nucleic acid of claim 1, wherein said nucleotide sequence is transcribed into an RNA molecule having a secondary structure that permits specific binding to at least one MIR-binding protein.
3. A purified myofibrillogenesis-inducing RNA (MIR) molecule comprising a ribonucleic acid sequence which is fully complementary over the full length of SEQ ID NO: 5 and induces myofibrillogenesis in living cells.
4. A vector comprising a purified nucleic acid cDNA of SEQ ID NO: 5 that is transcribed into a myofibrillogenesis-inducing RNA (MIR) molecule.
5. The vector of claim 4, wherein the purified nucleic acid further encodes a MIR-binding protein.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A liquid crystal display device comprising:
a first substrate;
a second substrate spaced apart from and opposite to the first substrate;
a first lower alignment layer formed on an upper surface of the first substrate;
a first upper alignment layer formed on a lower surface of the second substrate;
a second alignment layer formed in an array on either or both of an upper surface of the first lower alignment layer and a lower surface of the first upper alignment layer;
a polymer barrier positioned between the first substrate and the second substrate, the polymer barrier formed on the array of the second alignment layer; and
a liquid crystal positioned between the polymer barriers.
2. The liquid crystal display device of claim 1, wherein the second alignment layer comprises a second lower alignment layer formed on a first lower alignment layer, and a second upper alignment layer formed on a first upper alignment layer.
3. The liquid crystal display device of claim 1, wherein adhesion per unit area of each of the first upper alignment layer and the first lower alignment layer with the polymer barrier is lower than adhesion per unit area of the second alignment layer with the polymer barrier.
4. The liquid crystal display device of claim 1, wherein the first lower alignment layer and the first upper alignment layer comprise a compound having a hydrophobic functional group.
5. The liquid crystal display device of claim 1, wherein the second alignment layer comprises a compound having a hydrophilic functional group.
6. The liquid crystal display device of claim 1, wherein the first lower alignment layer, the first upper alignment layer, and the second alignment layer are composed of a polyimide-based compound.
7. The liquid crystal display device of claim 1, wherein the first lower alignment and the first upper alignment layers are a polyimide-based compound formed from at least one or more compounds of 1,4-PDA (1,4-phenylene diamine p-phenylenediamine), DAM (2,4-diamino mesitylene), m-TB-HG (2,2\u2032-dimethyl-4,4\u2032-diaminobiphenyl), and TFMB (2,2\u2032-bis(trifluoromethyl)-4,4\u2032-diaminobiphenyl) with at least one or more compounds of PMDA (1,2,4,5-benzenetetracarboxylic dianhydride), BPDA (4,4\u2032-biphthalic anhydride), 6FDA (4,4\u2032-(Hexafluoroisopropylidene)diphthalic anhydride), and NTDA (1,4,5,8-naphthalenetetracarboxylic dianhydride).
8. The liquid crystal display device of claim 1, wherein the second alignment layer is a polyimide-based compound formed from at least one or more compounds of ODA (4,4\u2032-oxydianiline), BDSA (4,4\u2032-diaminodiphenyl-2,2\u2032-disulfonic acid), HFBAPP (2,2\u2032-bis4-(4-aminophenoxy)phenylhexafluoropropane), and AHHFP (2,2-bis(3-amino-4-hydroxyphenyl)hexafluoropropane) with at least one or more compounds of BTDA (3,3\u2032-4,4\u2032-benzophenonetetracarboxylic dianhydride), TMA (trimellitic anhydride), and ODPA (4,4\u2032-oxydiphthalic anhydride).
9. The liquid crystal display device of claim 1, wherein the second alignment layer is patterned so that the second alignment layer corresponds to at least a portion of the polymer barrier.
10. The liquid crystal display device of claim 1, wherein the second alignment layer is patterned to match all of the polymer barrier.
11. The liquid crystal display device of claim 1, wherein the monomer is an acrylate-based compound.
12. A method for manufacturing a liquid crystal display device, the method comprising:
forming a first lower alignment layer on an upper surface of a first substrate;
forming a first upper alignment layer on a lower surface of a second substrate spaced apart from and opposite to the first substrate;
forming a second lower alignment layer on either or both of an upper surface of the first lower alignment layer or a lower surface of the first upper alignment layer, the second lower alignment layer formed in an array;
sealing the first substrate and the second substrate;
injecting a mixture including a liquid crystal and one or more of monomers between the first substrate and the second substrate; and
forming a polymer barrier between the second lower alignment layer and the second upper alignment layer from the injected one or more monomers, the polymer barrier formed on the array of the second alignment layer.
13. The method of claim of 12, wherein the forming of the first lower alignment layer and the forming of the first upper alignment layer comprise one of a dry coating process, a wet coating process, and a printing process.
14. The method of claim of 12, wherein the forming of the second lower alignment layer and the forming of the second upper alignment layer comprise a soft lithography process.
15. The method of claim of 12, wherein the forming of the second lower alignment layer and the forming of the second upper alignment layer comprise a printing process.
16. The method of claim 12, wherein the forming of the polymer barrier comprises polymerizing monomers using at least one of heat and light.
17. The method of claim of 12, wherein the polymer barrier is formed so as to correspond to the second lower alignment layer and the second upper alignment layer.
18. A liquid crystal display device comprising:
a first lower alignment layer;
a first upper alignment layer parallel to the first alignment layer;
a polymer barrier orthogonal to the first upper alignment layer and to the first lower alignment layer, the polymer barrier including a first end proximate to the first upper alignment layer and a second end proximate to the first lower alignment layer, the polymer barrier formed in an array; and
a first adhesive layer formed in the array of the polymer barrier between the polymer barrier and at least one of the first lower alignment layer and first upper alignment layer.
19. The liquid crystal display device of claim 18, further comprising a second adhesive layer between the second end of the polymer barrier and the second alignment layer
20. The liquid crystal display device of claim 18, wherein at least one of the adhesive layers comprises a hydrophilic functional group.
21. The liquid crystal display device of claim 18, wherein at least one of the first alignment layer and the second alignment layer comprises a hydrophobic functional group.
22. The liquid crystal display device of claim 18, wherein the alignment layer has an adhesive power of less than 0.05 Ncm and the adhesive layer has an adhesive power of more than 0.5 Ncm.
23. A method for manufacturing a liquid crystal display device, the method comprising:
forming a first upper alignment layer on an upper surface of a first substrate;
forming a first lower alignment layer on an lower surface of a second substrate spaced apart from and opposite to the first substrate;
forming an adhesive layer on at least one of the first upper alignment layer and the first lower alignment layer, the adhesive layer formed in an array;
injecting a mixture including a liquid crystal and one or more of monomers between the first substrate and the second substrate; and
forming a polymer barrier in the array between the adhesive layer and at least one of the first lower alignment layer and the first upper alignment layer.
24. The method of claim 23, wherein the adhesive layer is on both of the first upper alignment layer and the first lower alignment layer.
25. The method of claim 24, wherein the polymer barrier is between a first adhesive layer on the first upper alignment layer and a second adhesive layer on the first lower alignment layer.
26. The method of claim 23, wherein at least one of the adhesive layers comprises a hydrophilic functional group.
27. The method of claim 23, wherein at least one of the adhesive layers comprises a hydrophobic functional group.