1. An image sensing and displaying apparatus comprising:
a plurality of thin-film photoelectric transducer elements arranged in a matrix, each thin-film photoelectric transducer element emitting light in response to an electrical signal supplied thereto and outputting an electrical signal in response to light input thereto;
a display circuit which supplies an electrical signal to each of the plurality of thin-film photoelectric transducer elements;
a sensor circuit which receives an electrical signal from each of the plurality of thin-film photoelectric transducer elements; and
a switching circuit which switches the display circuit and the sensor circuit on each of the plurality of thin-film photoelectric transducer elements.
2. The image sensing and displaying apparatus according to claim 1, wherein each of the plurality of thin-film photoelectric transducer elements is connected to a first signal line, and the switching circuit connects either one of the display circuit and the sensor circuit to the first signal line.
3. The image sensing and displaying apparatus according to claim 2, wherein each of the plurality of thin-film photoelectric transducer elements comprises a switch element which permits or prevents communications of the electrical signals to the first signal line in accordance with an electrical signal supplied through a second signal line, and wherein the first signal line is commonly connected to some of the plurality of thin-film photoelectric transducer elements.
4. The image sensing and displaying apparatus according to claim 3, wherein the second signal line is commonly connected to some of the plurality of thin-film photoelectric transducer elements disposed in the same row, and the first signal line is commonly connected to some of the plurality of thin-film photoelectric transducer elements disposed in the same column.
5. The image sensing and displaying apparatus according to claim 1, wherein each of the plurality of thin-film photoelectric transducer elements comprises a pair of electrodes and an organic electroluminescent layer disposed between the pair of electrodes, and the electrical signals are one of supplied to and output from the pair of electrodes.
6. An image sensing and displaying apparatus comprising:
a plurality of pixels arranged in a matrix, each of the pixels including first and second thin-film photoelectric transducer elements which emit light in response to an electrical signal supplied thereto and output an electrical signal in response to light input thereto;
a display circuit which supplies an electrical signal to the first and second thin-film photoelectric transducer elements;
a sensor circuit which receives an electrical signal from the first and second thin-film photoelectric transducer elements; and
a switching circuit which switches the display circuit and the sensor circuit on each of the first and second thin-film photoelectric transducer elements.
7. The image sensing and displaying apparatus according to claim 6, wherein the first thin-film photoelectric transducer element is connected to a first signal line and the second thin-film photoelectric transducer element is connected to a second signal line, and the first and second signal lines are independently connected to either one of the display circuit and the sensor circuit by the switching circuit.
8. The image sensing and displaying apparatus according to claim 7, wherein each of the first and second thin-film photoelectric transducer elements comprises a switch element which permits or prevents communications of the electrical signals to the first and second signal lines in accordance with an electrical signal supplied through a third signal line, and wherein the first and second signal lines are commonly provided to some of the plurality of pixels disposed in the same row and the third signal line is commonly provided to some of the plurality of pixels disposed in the same column.
9. The image sensing and displaying apparatus according to claim 6, wherein each of the first and second thin-film photoelectric transducer elements comprises a pair of electrodes and an organic electroluminescent layer disposed between the pair of electrodes, and the electrical signals are one of supplied to and output from the pair of electrodes.
10. An image sensing and displaying apparatus comprising:
a plurality of pixels arranged in a matrix, each of the pixels including a first thin-film photoelectric transducer element which emits light in response to an electrical signal supplied thereto and a second thin-film photoelectric transducer element which outputs an electrical signal in response to light input thereto;
a display circuit which supplies an electrical signal to the first thin-film photoelectric transducer element; and
a sensor circuit which receives an electrical signal from the second thin-film photoelectric transducer element.
11. The image sensing and displaying apparatus according to claim 10, wherein the first thin-film photoelectric transducer element is connected to the display circuit via a first signal line and the second thin-film photoelectric transducer element is connected to the sensor circuit via a second signal line.
12. The image sensing and displaying apparatus according to claim 11, wherein each of the first and second thin-film photoelectric transducer elements comprises a switch element which permits or prevents communications of the electrical signals to the first and second signal lines in accordance with an electrical signal supplied through a third signal line, and wherein the first and second signal lines are commonly provided to some of the plurality of pixels disposed in the same row and the third signal line is commonly provided to some of the plurality of pixels disposed in the same column.
13. The image sensing and displaying apparatus according to claim 10, wherein each of the first and second thin-film photoelectric transducer elements comprises a pair of electrodes and an organic electroluminescent layer disposed between the pair of electrodes, and wherein the electrical signals are one of supplied to and output from the pair of electrodes.
The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.
1. A compound having the formula Ia:
or a pharmaceutically acceptable salt thereof, wherein
R1 is (1) heteroaryl selected from benzothiadiazolyl, thienyl, imidazolyl, pyridyl and pyrazolyl optionally substituted with one to four substituents independently selected from Rb; or (2) phenyl substituted at the 3-position optionally having a second substituent, wherein said substituents are independently selected from Rb, and provided that said second substituent is other than CH\u2550CHC(O)ORf;
R2 is
1) hydrogen,
2) C1-10alkyl,
3) C2-10alkenyl,
4) C2-10alkynyl,
5) aryl,
6) aryl-C1-10alkyl,
7) heteroaryl,
8) heteroaryl-C1-10alkyl,
wherein alkyl, alkenyl, and alkynyl are optionally substituted with one to four substituents independently selected from Ra; and aryl and heteroaryl optionally substituted with one to four substituents independently selected from Rb;
R3 is
1) hydrogen,
2) C1-10alkyl,
3) Cy, or
4) Cy-C1-10 alkyl,
wherein alkyl is optionally substituted with one to four substituents independently selected from Ra; and Cy is optionally substituted with one to four substituents independently selected from Rb;
R4 is
1) hydrogen,
2) C1-10alkyl,
3) C2-10alkenyl,
4) C2-10alkynyl,
5) Cy,
6) Cy-C1-10alkyl,
7) Cy-C2-10alkenyl,
8) Cy-C2-10alkynyl,
wherein alkyl, alkenyl and alkynyl are optionally substituted with one to four substituents selected from phenyl and Rx, and Cy is optionally substituted with one to four substituents independently selected from Ry; or
R3, R4 and the atoms to which they are attached together form a mono- or bicyclic ring containing 0-2 additional heteroatoms selected from N, O and S;
R5 is
1) hydrogen,
2) C1-10alkyl,
3) C2-10alkenyl,
4) C2-10alkynyl,
5) aryl,
6) aryl-C1-10alkyl,
7) heteroaryl,
8) heteroaryl-C1-10alkyl,
wherein alkyl, alkenyl and alkynyl are optionally substituted with one to four substituents selected from Rx, and aryl and heteroaryl are optionally substituted with one to four substituents independently selected from Ry; or
R4, R5 and the carbon to which they are attached form a 3-7 membered mono- or bicyclic ring containing 0-2 heteroatoms selected from N, O and S;
R6 and R7 are each independently selected from the group consisting of
1) a group selected from Rd, and
2) a group selected from Rx; or
R6, R7 and the atom to which both are attached, or R6, R7 and the two adjacent atoms to which they are attached, together form a 5-7 membered saturated or unsaturated monocyclic ring containing zero to three heteroatoms selected from N, O or S,
Ra is
1) Cy, or
2) a group selected from Rx;
wherein Cy is optionally subsituted with one to four substituents independently selected from Rc;
Rb is
1) a group selected from Ra,
2) C1-10 alkyl,
3) C2-10 alkenyl,
4) C2-10 alkynyl,
5) aryl C1-10alkyl,
6) heteroaryl C1-10 alkyl,
wherein alkyl, alkenyl, alkynyl, aryl, heteroaryl are optionally substituted with a group independently selected from Rc;
Rc is
1) halogen,
2) NO2,
3) C(O)ORf,
4) C1-4alkyl,
5) C1-4alkoxy,
6) aryl,
7) aryl C1-4alkyl,
8) aryloxy,
9) heteroaryl,
10) NRfRg,
11) NRfC(O)Rg,
12) NRfC(O)NRfRg, or
13) CN;
Rd and Re are independently selected from hydrogen, C1-10alkyl, C2-10 alkenyl, C2-10alkynyl, Cy and Cy C1-10alkyl, wherein alkyl, alkenyl, alkynyl and Cy is optionally substituted with one to four substituents independently selected from Rc; or
Rd and Re together with the atoms to which they are attached form a heterocyclic ring of 5 to 7 members containing 0-2 additional heteroatoms independently selected from oxygen, sulfur and nitrogen;
Rf and Rg are independently selected from hydrogen, C1-10alkyl, Cy and Cy-C1-10alkyl wherein Cy is optionally substituted with C1-10alkyl; or
Rf and Rg together with the carbon to which they are attached form a ring of 5 to 7 members containing 0-2 heteroatoms independently selected from oxygen, sulfur and nitrogen;
Ri
1) C1-10alkyl,
2) C2-10alkenyl,
3) C2-10alkynyl, or
4) aryl;
wherein alkyl, alkenyl, alkynyl and aryl are each optionally substituted with one to four substituents independently selected from Rc;
Rx is
1) \u2014ORd,
2) \u2014NO2,
3) halogen
4) \u2014S(O)mRd,
5) \u2014SRd,
6) \u2014S(O)2ORd,
7) \u2014S(O)mNRdRe,
8) \u2014NRdRe,
9) \u2014O(CRfRg)nNRdRe,
10) \u2014C(O)Rd,
11) \u2014CO2Rd,
12) \u2014CO2(CRfRg)bCONRdRe,
13) \u2014OC(O)Rd,
14) \u2014CN,
15) \u2014C(O)NRdRe,
16) \u2014NRdC(O)Re,
17) \u2014OC(O)NRdRe,
18) \u2014NRdC(O)ORe,
19) \u2014NRdC(O)NRdRe,
20) \u2014CRd(N\u2014ORe),
21) \u2014CF3,
22) oxo,
23) NRdC(O)NRd SO2Ri,
24) NRdS(O)mRe,
25) \u2014OS(O)2ORd, or
26) \u2014OP(O)(ORd)2;
Ry is
1) a group selected from Rx,
2) C1-10 alkyl,
3) C2-10 alkenyl,
4) C2-10 alkynyl,
5) aryl C1-10alkyl,
6) heteroaryl C1-10 alkyl,
7) cycloalkyl,
8) heterocyclyl;
wherein alkyl, alkenyl, alkynyl and aryl are each optionally substituted with one to four substituents independently selected from Rx;
Cy is cycloalkyl, heterocyclyl, aryl, or heteroaryl;
m is an integer from 1 to 2;
n is an integer from 1 to 10;
X is \u2014C(O)ORd;
Z is selected from \u2014C\u2014 and \u2014C\u2014C\u2014;
B is selected from the group consisting of
1) a bond,
2)\u2014C-
3)\u2014C\u2014C\u2014,
3)\u2014C\u2550C\u2014,
4) a heteroatom selected from the group consisting of nitrogen, oxygen, and sulfur; and
5) \u2014S(O)m\u2014;
with the proviso that R6R7 is not oxo when attached to the carbon between N and B.
2. A compound of claim 1 wherein Z is C.
3. A compound of claim 1 wherein B is C, C\u2550C, C\u2014C or S.
4. A compound of claim 1 wherein X is C(O)ORd.
5. A compound of claim 1 wherein R5 is H and R4 is C1-10 alkyl or Cy-C1-10alkyl, wherein alkyl is optionally substituted with one to four substituents selected from phenyl and RX, and Cy is optionally substituted with one to four substituents independently selected from RY; or R4, R5 and the carbon to which they are attached together form a 3-7 membered mono- or bicyclic carbon only ring.
6. A compound of claim 5, wherein R4 is phenyl-C1-3 alkyl, wherein phenyl is optionally substituted with one or two groups selected from RY.
7. A compound of claim 1, having the formula Ib:
wherein R2 is H or C1-6 alkyl, and R1, R2, R3, R4 and R5 and X are as defined in claim 1.
8. A compound of claim 7, wherein X is CO2H; R1 is phenyl substituted at the 3-position optionally having a second substituent, wherein said substituents are independently selected from Rb; R2 is H; R3 is H or C1-3 alkyl; R4 is phenyl-C1-3alkyl, wherein phenyl is optionally substituted with one or two groups selected from RY; and R5 is H.
9. A compound of claim 1, having the formula Ic:
wherein R2 is H or C1-3 alkyl; R6 is H, C1-6 alkyl, aryl, ORd, SRd, NRdRe, or NRdC(O)Re; B is S, C\u2550C, C or C\u2014C; R3 is H or C1-6alkyl, Rb and RY are as defined in claim 1.
10. A compound of claim 9 wherein B is C and Rb is halogen, C1-10alkoxy, cyano, or trifluoromethyl.
11. A compound of claim 1 selected from the group consisting of:
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-leucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-arginine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-glutamic acid;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-glycine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-(1-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-\u03b1-t-butylglycine;
N-(3,4-dimethoxybenzenesulfonyl) 1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-3-(2-thienyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-cyclohexylalanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-3,3-diphenylalanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-proline;
N-(3,4-dimethylbenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-cysteine;
N-(2,5-dichlorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-phenylalanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-glutamine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-(4-nitrophenyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-asparagine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-methionine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-homophenylalanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(D)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-(4-fluorophenyl)alanine;
N-(3-toluenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-chloro-3-nitrobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl) 1,2,3,4-tetrahydroisoquinoline-3 (S)-carbonyl-(L)-norleucine;
N-(3,4-dichlorobenzenesulfonyl) 1,2,3,4-tetrahydroisoquinoline-3(S)-carbony(L)-norleucine;
N-(2,3-dichlorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2,5-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-serine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-isoleucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-tryptophan;
N-(2,1,3-benzothiadiazole-4-sulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-tryptophan;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-3-(3-pyridyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-3-(2-naphthyl)alanine, ethyl ester;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(R)-carbonyl-(D)-norleucine;
N-(3-nitrobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(3-trifluoromethylbenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2-thienylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L) -N-methylleucine;
N-(3,4-dimethoxybenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-citrulline;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-(3-iodo)tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(3-pyridyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-glutamic acid;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-arginine;
N-(N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl)-1-amino-cyclopentane-1-carboxylic acid;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(3,4-dichlorophenyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(2-naphthyl)alanine, ethyl ester;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(4-bromophenyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(4-nitrophenyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(4-thiazolyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(2-chlorophenyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(4-chlorophenyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(4-cyanophenyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-tyrosine, O-sulfate;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3,5-diiodotyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-aspartic acid;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-tryptophan;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-methionine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-prolyl-(L)-norleucine;
N-(3,5-di(trifluoromethyl)benzenesulfonyl)-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-thiaprolyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-thiaprolyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-pipecolyl-(L)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-pipecolyl-(L)-norleucine, ethyl ester, N-(3,5-dichlorobenzenesulfonyl)-(L)-pipecolyl-(L)-homophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-pipecolyl-(L)-(3-iodo)tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-pipecolyl-(L)-3-(2-naphthyl)alanine;
N-(3,5-di(trifluoromethyl)benzenesulfonyl)-(L)-pipecolyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-pipecolyl-(L)-3-(2-naphthyl)alanine, ethyl ester;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-octahydroisoquinoline-3-carbonyl-(L)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-azetidine-2-carbonyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl)-(L)4(S)-hydroxyprolyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-4(S)-hydroxyprolyl-(L)-norleucine;
N-(3,4-dimethoxybenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-norleucine;
N-(3-bis(N,N-benzenesulfonyl)aminobenzenesulfonyl)-(L)-prolyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(4-pyridyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-3-(2-naphthyl)alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-3-iodotyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-thiaprolyl-(L)-3-(2-naphthyl)alanine;
N-(3-fluorobenzenesulfonyl)-(L)-pipecolyl-(L)-3-(2-naphthyl)alanine;
N-(3-fluorobenzenesulfonyl)-(L)-thiaprolyl-(L)-4-fluorophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-4-fluorophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-pipecolyl-(L)-4-fluorophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-tyrosine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-prolyl-(L)-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-tyrosine;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-pipecolyl-(L)-4-fluorophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-tyrosine, O-tert-butyl ether;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-tyrosine, O-tert-butyl ether;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-tyrosine
N-(3,5-dichlorobenzenesulfonyl)-(L)-3(S)-methyl-prolyl-(L)-4-fluorophenylalanine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-tyrosine, O-tert-butyl ether;
N-(3-chlorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-tyrosine, O-tert-butyl ether;
N-(3-chlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-tyrosine;
N-(3-chlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-tyrosine, O-tert-butyl ether;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-prolyl-(L)-3-iodotyrosine;
N-(3-chlorobenzenesulfonyl)-(L)-prolyl-(L)-3-iodotyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-prolyl-(L)-3-phenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-prolyl-(L)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-phenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-phenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-phenylalanine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-3-(4-pyridyl)alanine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-thiaprolyl-(L)-3-(4-pyridyl)alanine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-4-fluorophenyl-alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-phenylalanine;
N-(3-trifluoromethylbenzenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3-trifluoromethylbenzenesulfonyl)-(L)-thiaprolyl-(L)-4-fluorophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-tyrosine, O-phosphoric acid;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-tyrosine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-thiaprolyl-(L)-tyrosine;
N-(N1-methyl-4-imidazolesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(D)-prolyl-(D)-4-fluorophenylalanine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-3-(4-pyridyl)alanine;
N-(5-(5-trifluoromethyl-2-pyridylsulfonyl)-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(5-(N-(4-chlorobenzoyl)aminomethyl))-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(5-(3-(1\u2032-methyl-5-trifluoromethyl-pyrazoyl))-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3-fluorobenzenesulfonyl)-2(S)-methylprolyl-(L)-O-tert-butyl-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)4(R)-aminoprolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-4(S)-aminoprolyl-(L)-4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-4-fluorophenylalanine;
N-(4-bromo-5-chloro-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-3,5-di iodotyrosine;
N-(5-benzoylaminomethyl-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenyl-alanine;
N-(3-chlorobenzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(5-benzenesulfonyl-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3-bromo-5-chloro-2-thiophenesulfonyl)-(L)-prolyl-(L)-4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-3,4-dehydroprolyl-(L)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-homophenylalanine;
N-(4-benzenesulfonyl-2-thiophenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(5-benzoylaminomethyl-2-thiophenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(5-benzenesulfonyl-2-thiophenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-thiaprolyl-(L)-O-tert-butyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-cysteine, amide;
N-(1-methyl-4-imidazolylsulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(5-(4-trifluoromethylbenzenesulfonyl)-2-thiophenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(3-bromobenzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-prolyl-(L)-3-fluorophenylalanine;
N-(5-chloro-2-thiophenesulfonyl)-(L)-prolyl-(L)4-fluorophenylalanine;
N-(3-chlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methylprolyl-(L)-O-tert-butyl-tyrosine;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-hydroxyprolyl-(L)-tyrosine-O-sulfate;
N-(3-chlorobenzenesulfonyl)-(L)-thiaprolyl-(L)-tyrosine-O-sulfate;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-cysteine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-N-methyl-isoleucine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-O-tert-butyl-tyrosine;
N-(3-chlorobenzenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-O-tert-butyl-tyrosine;
N-(3-cyanobenzenesulfonyl)-(L)-prolyl-(L)-tyrosine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-O-tert-butyl-tyrosine;
N-(4,5-dichloro-2-thiophenesulfonyl)-(L)-4(R)-aminoprolyl-(L)-4-fluorophenyl-alanine;
N-(3-fluorobenzenesulfonyl)-(L)-5(R)-phenyl-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-3(R)-phenyl-prolyl-(L)-4-iodophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carbonyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-1,3-dihydro isoindolyl-1-carbonyl-(L)-4-fluorophenylalanine;
N-(3-ethoxycarbonyl-benzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(3-(4-benzophenonyl-carbonylamino)-benzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-3.1.0-3-azabicyclohexane-2-carbonyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl))-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3,4-dimethoxybenzenesulfonyl))-(L)-pipecolyl-(L)-tryptophan;
N-3,5-di(trifluoromethyl)benzenesulfonyl)-(L)-prolyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(3-trifluoromethylbenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(3-chlorobenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(3-trifluoromethylbenzenesulfonyl))-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3-nitrobenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(3-cyanobenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl))-(L)-prolyl-(L)-tryptophan;
N-(3-methylbenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(3,5-dichlorobenzenesulfonyl))-(L)-3(S)-methyl-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3-chlorobenzenesulfonyl)-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3-fluorobenzenesulfonyl))-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3,5-dichlorobenzenesulfonyl))-(L)-2-methyl-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3-fluorobenzenesulfonyl)-(L)-5,5-dimethyl-prolyl-(L)-3-(2-naphthyl)alanine;
N-(3-fluorobenzenesulfonyl)-(L)-prolyl-(L)-4-iodophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-phenylalaninamide-N-methylsulfonamide;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-iodophenylalanine;
N-(3-fluorobenzenesulfonyl)-(L)-prolyl-(L)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-5-methylprolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-3-phenylazetidinylcarbonyl-(L)4-fluoro-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-allylprolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-phenylalanine;
N-(3-trifluoromethylbenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-nitro-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-3(R)-methyl-prolyl-(L)-4-fluorophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-cyanophenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)4-(aminocarbonyl)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-3(R)-methyl-prolyl-(L)-4-(N-t-butoxycarbonylaminomethyl)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-3(R)-methyl-prolyl-(L)-4-(aminomethyl)-phenylalanine;
N-(3-tri fluoro methylphenyl sulfonyl)-(L)-2 (S)-methyl-prolyl-(L)-4-acetaminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(N\u2032-(2-toluyl)ureido)phenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(N\u2032-(4\u2032-fluorophenylsulfonyl)ureido)phenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(ethoxycarbonyl)aminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(4\u2032-(N\u2032-(2-toluyl)ureido)phenylacetyl)aminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(4\u2032-fluorophenylsulfonyl)aminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(phenylacetyl)aminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)4-(4\u2032-fluorobenzoyl)aminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(isobutyloxycarbonyl)aminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)4-methylsulfonylaminophenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(N\u2032-(4-fluorophenyl)ureido)phenylalanine;
N-(3-trifluoromethylbenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(N-(1,1-dioxo-1,2-isothiazolidinyl)-phenylalanine;
N-(3-trifluoromethylphenylsulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(N\u2032-(4-(2-oxo-1-pyrrolidinyl)-phenylalanine;
N-(3,5-dichorobenzenesulfonyl)-(L)-prolyl-(L)-4-(4\u2032-fluorobenzoyl)phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4\u2032-(2-methoxybenzoyl)phenylalanine;
N-(3,5-dichorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(4\u2032-fluorobenzoyl)phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(4-fluorobenzyl)phenyl alanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(2-methoxybenzyl)phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(2-nitrophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(4-nitrophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(2-nitrophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(2-aminophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(2-acetylaminophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-4-(4-acetylaminophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methylprolyl-(L)-4-(2-acetylaminophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-2-(S)-methyl-(L)-prolyl-4-(2-cyanophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-2-(S)-methyl-(L)-prolyl-4-(4-cyanophenoxy)-phenylalanine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-methyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-benzyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-n-butyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-cyanomethyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(2-methoxyethyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(2-ethoxyethyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(1-pyrrolidinylcarbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(tert-butyl acetate)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(4-morpholinyl-carbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(1-(2-propanonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(1-pyrrolidinylcarbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(tert-butyl acetate)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(2-ethoxyethyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(acetic acid)-tyrosine, methyl ester;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(acetic acid)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(1-(2-propanonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(1-pyrrolidinylcarbonyl)-tyrosine, methyl ester;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(4-morpholinyl-carbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(2-pyrrolylcarbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(N-phenyl-N-methylaminocarbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(N,N-diethyl-aminocarbonyl)-tyrosine;
N-(3-chlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(4-morpholinyl-carbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-O-(N,N-diisopropyl-aminocarbonyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(benzoyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(cyclopentanoyl)-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-prolyl-(L)-O-(5-tetrazoly)methyl-tyrosine;
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-Ne-benzyl-histidine; and
N-(3,5-dichlorobenzenesulfonyl)-(L)-2(S)-methyl-prolyl-(L)-4-(5-((1H,3H)-1,3-dimethylpyrimidine-2,4-dione))-phenylalanine.
12. A compound selected from the group consisting of:
N-(2,4-dinitrobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2-mesitylenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-chlorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3 (S)-carbonyl-(L)-norleucine;
N-(N\u2032-acetylsulfanilyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-fluorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-nitrobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-trifluoromethylbenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2,6-dichlorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2,4-difluorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2-cyanobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2-trifluoromethylbenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(2,4-dichlorobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-cyanobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(4-iodobenzenesulfonyl)-1,2,3,4-tetrahydroisoquinoline-3(S)-carbonyl-(L)-norleucine;
N-(5-benzenesulfonyl-2-thiophenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(3-fluorobenzenesulfonyl)-(L)-thiaprolyl-(L)-O-tert-butyl-tyrosine;
N-(4-methoxybenzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(1(R)-(+)-10-camphorsulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(1(S)-(+)-10-camphorsulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(4-(fluorescien-4-carbonylamino)benzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(4-iodobenzenesulfonyl)-(L)-prolyl-(L)4-benzoyl-phenylalanine;
N-(3-(6-(biotinylamino)-n-hexanoyl)-aminobenzenesulfonyl)-(L)-prolyl-(L)-O-tert-butyl-tyrosine;
N-(4-nitrobenzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(4-(benzoylamino)benzenesulfonyl))-(L)-prolyl-(L)-norleucine;
N-(4-methoxy-3,5-dinitrobenzenesulfonyl)-(L)-prolyl-(L)-norleucine;
N-(4-N\u2032-phenylureidobenzenesulfonyl)-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(4-N\u2032-(2-toluyl)ureidobenzenesulfonyl)-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-(4-N\u2032-benzylureidobenzenesulfonyl)-(L)-prolyl-(L)-3-(2-naphthyl)alanine;
N-benzenesulfonyl-(L)-prolyl-2-amino-2-norbornanecarboxylic acid;
N-benzenesulfonyl-(L)-prolyl-3(R)-methyl-phenylalanine;
N-benzenesulfonyl-(L)-prolyl-(L)-2,3-methano-phenylalanine; and
N-benzenesulfonyl-(L)-prolyl-(D)-2,3-methano-phenylalanine.