1461176094-9f88e04a-119e-4b1e-ad4e-8f87a90ea715

What is claimed is:

1. A single drum type heat-sensitive adhesive activating labeler comprising:
(a) a label sheet;
(b) a printer that prints a necessary item on a surface opposite to an adhesive surface of the label sheet;
(c) a feed roll that feeds a label piece to a suction hole of every other position of label suction holes of an adhering drum provided in front of the printer;
(d) a label sheet cutter disposed in from of the feed roll at a position where at least a tip of a label piece cut from the label sheet by the cutter is brought into contact with the suction hole of the adhering drum;
(e) a label adhering drum including a drum disposed in front of the cutter, having the label suction holes disposed at equal intervals in an odd number of places of a peripheral surface of the drum, and a ventilation hole having an open hole at one end opened to a top surface of the drum and another end connected to a pressure reducing device, the ventilation hole and the label suction holes being communicated with each other, and a closing rod freely detachably inserted from the opening of the ventilation hole at the top surface to close an unnecessary label suction hole;
(f) a feeder that feeds an article, to which the label piece is adhered, in synchronization with the label piece sucked to a label suction hole of the every other position;
(g) a pressing device provided at a position opposite to the drum in front of the cutter to press the article fed to the adhering drum and adhere the label piece according to rotation of the drum; and
(h) a heat-sensitive adhesive activation device to adhere the label piece onto the article, disposed along peripheral of the label adhering drum except locations where the label adhering drum sucks the label piece and where the article is pressed onto the adhering drum.
2. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the label suction holes disposed in the drum are formed into suction hole groups including a plurality of suction holes.
3. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the label sheet cutter includes a latch and a cutting blade disposed in the vicinity of suction holes at a rear part of the suction hole groups of the adhering drum when seen from an advancing direction of the drum.
4. A single drum type heat-sensitive adhesive activating labeler according to claim 1, the label sheet cutter includes a rotary blade and a rotary roller provided in the vicinity of the adhering drum opposite to each other by sandwiching the label sheet.
5. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the label suction holes are disposed in odd number of places of the peripheral surface of the drum and include wide suction portions for sucking large label pieces.
6. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the closing rod is freely detachably inserted into the open hole to close the unnecessary label suction hole and has a length reaching a suction hole of a lowermost layer from the open hole.
7. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the closing rod has a head that is large enough not to be inserted into the open hole.
8. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the closing rod includes an adjustable portion that length of insertion of the closing rod from the open hole is adjustable.
9. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the closing rod comprises a hollow part with a wall, the wall includes a through-hole at a position that matches the suction hole, the hollow part further has an opening end that is communicated with a ventilation path.
10. A single drum type heat-sensitive adhesive activating labeler according to claim 9, wherein the closing rod includes a plurality of through-holes that match suction holes suited for a label size.
11. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the pressure reducing device is connected to the suction holes of the drum, and stops suction at a stage where the article is pressed to the adhering drum, and the label piece is adhered by rotation of the drum.
12. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the heat-sensitive adhesive activation device is a far-infrared ray heater adapted to activate heat-sensitive adhesive of the label piece by radiant heat of far-infrared rays without contact.
13. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein the pressing device comprises an arc shaped pressing member provided along the drum peripheral surface to guide the fed-in article to the adhering drum and press the article by rotation of the drum.
14. A single drum type heat-sensitive adhesive activating labeler according to claim 1, wherein a failed printing label adhered article detecting and discharging device is provided in a position in front of the pressing device.
15. A continuous label adhering method by a single drum type heat-sensitive adhesive activating labeler, comprising the steps of:
sucking the label piece with a label suction hole of a single drum type heat-sensitive adhesive activating labeler specified in any one of claims 1 to 14;
activating the adhesive by a heat-sensitive adhesive activation device;
adhering the label piece to the article fed by the pressing device, to which the label piece is to be adhered;
rotating the label suction hole once without having the label piece;
returning to a label sucking position to suck another label piece;
repeating the steps of sucking the another label piece, activating adhesive of the another label piece by the heat-sensitive adhesive activation device, and adhering the another label piece to another article fed by the pressing device, to which the another label piece is to be adhered.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. An electronic image pickup apparatus comprising:
a color image pickup element which has a plurality of drive modes including at least a first drive mode and a second drive mode;
a color-conversion parameter storage section which stores a first color-conversion parameter for color-converting a color data acquired by the color image pickup element in the first drive mode;
a color-conversion parameter computing section which computes from the first color-conversion parameter a second color-conversion parameter in order to color-convert a color data acquired by the color image pickup element in the second drive mode;
a computation parameter storage section which stores a computation parameter for computing the second color-conversion parameter; and
a color-conversion section which color-converts the color data acquired by the color image pickup element in the first drive mode according to the first color-conversion parameter and also color-converts the color data acquired by the color image pickup element in the second drive mode according to the second color-conversion parameter.
2. The apparatus according to claim 1, wherein the first drive mode includes a drive mode for picking up a still image.
3. The apparatus according to claim 1, wherein
the second drive mode includes a drive mode for displaying a live view.
4. The apparatus according to claim 1, wherein
the color-conversion parameter computing section computes the second color-conversion parameter by linear transformation and the color-conversion section color-converts the color data by linear transformation.
5. An electronic image pickup apparatus, comprising:
a color image pickup element which has a plurality of drive modes including at least a first drive mode and a second drive mode;
an optical lens which converges light from a subject to the color image pickup element;
a spectral sensitivity characteristics storage section which stores the spectral sensitivity characteristics corresponding to the first drive mode of the color image pickup element;
a first color-conversion parameter computing section which computes a first color-conversion parameter for color-converting a color data acquired by the color image pickup element in the first drive mode according to the spectral sensitivity characteristics;
a second color-conversion parameter computing section which computes from the first color-conversion parameter the second color-conversion parameter for color-converting a color data acquired by the color image pickup element in the second drive mode;
a computation parameter storage section which stores the computation parameter for computing the second color-conversion parameter; and
a color-conversion section which color-converts the color data acquired by the color image pickup element in the first drive mode according to the first color-conversion parameter and also color-converts the color data acquired by the color image pickup element in the second drive mode according to the second color-conversion parameter.
6. The apparatus according to claim 5, wherein
the first drive mode includes a drive mode for picking up a still image.
7. The apparatus according to claim 5, wherein
the second drive mode includes a drive mode for displaying a live view.
8. The apparatus according to claim 5, wherein
the second color-conversion parameter computing section computes the second color-conversion parameter by linear transformation and the color-conversion section color-converts the color data by linear transformation.
9. The apparatus according to claim 5, wherein
the optical lens is adapted to be detachably fitted to the electronic image pickup apparatus and includes a spectral transmittance storage section for storing the spectral transmittance of the optical system of the optical lens; and
the first color-conversion parameter computing section computes the first color-conversion parameter from the spectral transmittance and the spectral sensitivity characteristics.
10. An electronic image pickup apparatus, comprising:
a color image pickup element which has a plurality of drive modes including at least a first drive mode and a second drive mode;
an optical lens which converges light from a subject to the color image pickup element;
a spectral sensitivity characteristics storage section which stores a first spectral sensitivity characteristics corresponding to the first drive mode of the color image pickup element;
a spectral sensitivity characteristics computing section which computes a second spectral sensitivity characteristics corresponding to the second drive mode of the color image pickup element according to the first spectral sensitivity characteristics;
a spectral sensitivity characteristics computation parameter storage section which stores the computation parameter for computing the second spectral sensitivity characteristics;
a color-conversion parameter computing section which computes a first color-conversion parameter for converting a color data acquired by the color image pickup element in the first drive mode according to the first spectral sensitivity characteristics and also computing a second color-conversion parameter for converting a color data acquired by the color image pickup element in the second drive mode according to the second spectral sensitivity characteristics;
a color-conversion computation parameter storage section which stores the computation parameter for computing the first and second color-conversion parameters; and
a color-conversion section which color-converts the color data acquired by the color image pickup element in the first drive mode according to the first color-conversion parameter and also color-converts the color data acquired by the color image pickup element in the second mode according to the second color-conversion parameter.
11. The apparatus according to claim 10, wherein
the first drive mode includes a drive mode for picking up a still image.
12. The apparatus according to claim 10, wherein
the second drive mode includes a drive mode for displaying a live view.
13. The apparatus according to claim 10, wherein
the spectral sensitivity characteristics computing section computes the second spectral sensitivity characteristics by linear transformation and the computation parameter stored in the spectral sensitivity characteristics computation parameter storage section is a linear transformation coefficient.
14. The apparatus according to claim 10, wherein
the optical lens is adapted to be detachably fitted to the electronic image pickup apparatus and includes a spectral transmittance storage section for storing the spectral transmittance of the optical system of the optical lens; and
the spectral sensitivity,characteristics computing section computes the second spectral sensitivity characteristics from the spectral transmittance, the first spectral sensitivity characteristics and the computation parameter stored in the spectral sensitivity characteristics computation parameter storage section.
15. An electronic image pickup method for a color image pickup element having a plurality of drive modes including at least a first drive mode and a second drive mode, the method comprising:
computing a second color-conversion parameter for color-converting the color data acquired by the color image pickup element in the second drive mode by subjecting a first color-conversion parameter to linear transformation; and
color-converting a color data acquired by the color image pickup element in the first drive mode by subjecting the color data to linear transformation according to the first color-conversion parameter and also color-converting a color data acquired by the color image pickup element in the second drive mode by subjecting the color data to linear transformation according to the second color-conversion parameter.
16. An electronic image pickup method for a color image pickup element having a plurality of drive modes including at least a first drive mode and a second drive mode, the method comprising:
computing a first color-conversion parameter for color-converting a color data acquired by the color image pickup element in the first drive mode according to a spectral sensitivity characteristics corresponding to the first drive mode of the color image pickup element;
computing a second color-conversion parameter for color-converting a color data acquired by the color image pickup element in the second drive mode by subjecting the first color-conversion parameter to linear transformation; and
color-converting a color data acquired by the color image pickup element in the first drive mode by subjecting the color data to linear transformation according to the first color-conversion parameter and also color-converting a color data acquired by the color image pickup element in the second drive mode by subjecting the color data to linear transformation according to the second color-conversion parameter.
17. An electronic image pickup method for a color image pickup element having a plurality of drive modes including at least a first drive mode and a second drive mode, the method comprising:
computing a second spectral sensitivity characteristics corresponding to the second drive mode of the color image pickup element by subjecting a first spectral sensitivity characteristics corresponding to the first drive mode of the color image pickup element to linear transformation;
computing a first color-conversion parameter for color-converting a color data acquired by the color image pickup element in the first drive mode according to the first spectral sensitivity characteristics;
computing a second color-conversion parameter for converting a color data acquired by the color image pickup element in the second drive mode according to the second spectral sensitivity characteristics; and
color-converting the color data acquired by the color image pickup element in the first drive mode to color-conversion according to the first color-conversion parameter and also color-converting the color data acquired by the color image pickup element in the second drive mode to conversion according to the second color-conversion parameter.

1461176083-349833b6-e622-4500-b392-41721ae89fc5

1. A method of monitoring an image forming apparatus, comprising the steps of:
receiving, at a location which is remote from the image forming machine, first parameters representing a condition of at least one part of said image forming apparatus;
storing said first parameters;
receiving, at the location which is remote from the image forming apparatus, second parameters after at least one image forming operation is executed by the image forming machine, said second parameters representing said condition of said at least one part of said image forming apparatus related to at least one of said first parameters;
comparing said first parameters and said second parameters; and
controlling a display of said condition on a terminal that is remote from said image forming apparatus using a result of the comparing step.
2. The method of claim 1, further comprising the steps of:
storing a tolerance of said condition;
comparing said tolerance to said second parameter; and
controlling a display of said condition represented by said second parameter in a highlighted manner on said terminal, when the second parameter is determined to be outside of said tolerance by said comparing step.
3. The method of claim 1, wherein said step of receiving said first parameter comprises:
receiving said first parameter from said image forming apparatus after said image forming apparatus is operated to execute a test operation when said image forming apparatus is installed at a user site so that said first parameter represents an acceptable condition existing at a time of installation.
4. The method of claim 1, further comprising the steps of:
receiving, at the location which is remote from the image forming apparatus, a message indicating an occurrence of an error in said image forming apparatus; and
sending at least one email from the location which is remote to at least one email address which has been stored in a memory to indicate that said message has been received from said image forming apparatus.
5. The method of claim 4, further comprising the steps of:
receiving said email at said remote terminal;
instructing, at the remote terminal, that at least said second parameter is to be transmitted to the remote terminal;
transmitting the second parameter to the remote terminal; and
displaying said second parameter on said remote terminal.
6. The method of claim 5, further comprising the steps of:
adjusting, at the remote terminal, said second parameter to form an updated second parameter;
sending, to said image machine, said updated parameter; and
whereby said updated second parameter modifies said condition of said image forming apparatus.
7. An image forming machine monitoring system, comprising:
means for receiving, at a location which is remote from the image forming machine, a first parameter representing a condition of at least one part of said image forming apparatus;
means for storing said first parameter;
means for receiving, at the location which is remote from the image forming apparatus, a second parameter after at least one image forming operation is executed by the image forming machine, said second parameter representing said condition of said at least one part of said image forming apparatus related to at least one of said first parameter;
means for comparing said first parameter and said second parameter to form compared data; and
means for controlling a display of said condition on a terminal that is remote from said image forming apparatus based on said compared data.
8. The system of claim 7, further comprising means for storing a tolerance of said condition;
means for comparing said tolerance to said second parameter to form compared data; and
means for controlling a display of said condition represented by said second parameter in a highlighted manner on said terminal, when said compared data indicates the second parameter is determined to be outside of said tolerance.
9. The system of claim 7, wherein said first parameter is transmitted from said image forming apparatus after said image forming apparatus is operated to execute a test operation when said image forming apparatus is installed at a user site so that said first parameter represents an acceptable condition existing at a time of installation.
10. The system of claim 7 further comprising, means for receiving, at the location which is remote from the image forming apparatus, a message indicating an occurrence of an error in said image forming apparatus; and
means for sending at least one email from the location which is remote to at least one email address which has been stored in a memory to indicate that said message has been received from said image forming apparatus.
11. The system of claim 10 further comprising means for receiving said email at said remote terminal;
means for instructing, at the remote terminal, that at least said second parameter is to be transmitted to the remote terminal;
means for transmitting the second parameter to the remote terminal; and
means for displaying said second parameter on said remote terminal.
12. The system of claim 11 further comprising means for adjusting, at the remote terminal, said second parameter to form an updated second parameter;
means for sending, to said image machine, said updated parameter; and
wherein said updated second parameter modifies said condition of said image forming apparatus.

The claims below are in addition to those above.
All refrences to claim(s) which appear below refer to the numbering after this setence.

1. A compound of formula (I)
or a salt or N-oxide thereof;
wherein R3 is aryl or heteroaryl, each optionally substituted; X3 and X4 are
independently CH or N;
X5 is selected from the group consisting of CR12R13, O, S, SO, SO2, and NR14 wherein R12 and R13 are independently selected from H, OH, and lower alkyl, or together form an oxo group;
R4 is selected from the group consisting of OH, acyl, formyl, sulfonyl, alkoxy, carboxylate, haloalkyl, halogen, cyano, nitro, trifluoromethoxy, difluoromethoxy, and fluoromethoxy;
R\u2032, R5, R6 and R14 are independently selected from the group consisting of H, lower alkyl, Rp, cycloalkyl and aryl, and wherein at least one of R\u2032, R5, R6 and R14 is Rp linked via \u2014C(O)O\u2014, \u2014C(S)O\u2014, -C(O)S\u2014, \u2014C(S)S\u2014, \u2014C(O)NH\u2014 or \u2014C(S)NH\u2014;
Rp is \u2014(CR1R2)n\u2014R;
R is selected from the group consisting of acetate, amino, dialkylamino, \u2014C(O)OH, alkyl, allyl, cycloalkyl, cycloheteroalkyl, aryl, heteroaryl, phenylalkaryl and heteroarylalkyl, each of which is optionally substituted;
R1 and R2 are each independently selected from the group consisting of H, OH, \u2014OR11, NR15R15, halo, lower alkyl, C(O)O-alkyl, \u2014C(O)OH, \u2014OP(\u2550O)(OR11)2, \u2014OC(\u2550O)OR11, \u2014OC(\u2550O)R11, cycloalkyl, aryl, and heteroaryl or together form an oxo, wherein each R15 is independently selected from the group consisting of H, lower alkyl, prenyl, allyl, \u2014C(O))-alkyl, cycloalkyl, aryl, heteroaryl, alkaryl and alkheteroaryl, or two of R15 combine to form an optionally substituted cycloheteroalkyl;
each R11 is independently H or lower alkyl;
n is an integer from 0 to 10;
R7 and R8 are independently selected from the group consisting of H, halogen, lower alkyl, cycloalkyl, aryl, and heteroaryl; and
R9 and R10 are independently selected from the group consisting of H, halogen, \u2014OH, -alkoxy, lower alkyl, cycloalkyl, aryl, and heteroaryl wherein R7 and R8, or R9 and R10 together form an oxo group, and wherein R9 or R10 are not \u2014OH or alkoxy when X5 is NR14.
2. A compound of formula (II)
or a salt andor N-oxide thereof,
wherein X1 is selected from the group consisting of O, S, and NR11 wherein R11 is H or lower alkyl;
X2 is O or S;
X3 and X4 are independently CH or N;
X5 is selected from the group consisting of CR12R13, O, S , SO, SO2, and NR14 wherein R12 and R13 are independently selected from H, OH, and lower alkyl, or together form an oxo group, and R14 is H or lower alkyl;
R is selected from the group consisting of acetate, amino, dialkylamino, \u2014C(O)OH, alkyl, allyl, cycloalkyl, cycloheteroalkyl, aryl, heteroaryl, phenylalkaryl and heteroarylalkyl, each of which is optionally substituted;
R1 and R2 are each independently selected from the group consisting of H, OH, \u2014OR11, NR15R15, halo, lower alkyl, \u2014C(O)O-alkyl, \u2014C(O)OH, \u2014OP(\u2550O)(OR11)2, \u2014OC(\u2550O) OR11, \u2014OC(\u2550O)R11, cycloalkyl, aryl, and heteroaryl or together form an oxo, wherein each R15 is independently selected from the group consisting of H, lower alkyl, prenyl, allyl \u2014C(O)O-alkyl, cycloalkyl, aryl, heteroaryl, alkaryl and alkheteroaryl, or two of R15 combine to form an optionally substituted cycloheteroalkyl;
R3 is aryl or heteroaryl, each optionally substituted;
R4 is selected from the group consisting of OH, acyl, formyl, sulfonyl, alkoxy, carboxylate, haloalkyl, halogen, cyano, nitro, trifluoromethoxy, difluoromethoxy, and fluoromethoxy;
R5 and R6 are independently selected from H, lower alkyl, cycloalkyl or aryl;
R7, R8, R9, and R10 are independently selected from the group consisting of H, OH, halogen, lower alkyl, cycloalkyl, aryl, and heteroaryl, or wherein R7 and R8 or R9 and R10 together form an oxo group; and
n is an integer from 0 to 10.
3. The compound of claim 2, wherein X1 is 0.
4. The compound of claim 3, wherein X2 is 0.
5. The compound of claim 2, wherein R3 is optionally substituted aryl.
6. The compound of claim 5, wherein aryl is alkoxyphenyl, dialkoxyphenyl, or trialkoxyphenyl.
7. The compound of claim 6, wherein trialkoxyphenyl is trimethoxyphenyl.
8. The compound of claim 2, wherein R4 is OH, halogen, cyano, nitro, trifluoromethyl, difluoromethyl, fluoromethyl, trifluoromethoxy, difluoromethoxy, or fluoromethoxy.
9. The compound of claim 8, wherein R4 is F.
10. The compound of claim 2, wherein R5 and R6 are H.
11. The compound of claim 2, wherein X4 is CH.
12. The compound of claim 2, wherein X4 is N.
13. The compound of claim 2, wherein X5 is CH2 or O.
14. The compound of claim 2, wherein R7 and R8 are H or together form the oxo group.
15. The compound of claim 2, wherein R9 and R10 are methyl.
16. The compound of claim 2, wherein R is cycloheteroalkyl.
17. The compound of claim 16, wherein R is substituted or unsubstituted morpholine, or substituted or unsubstituted pyrrolidine.
18. The compound of claim 2, wherein R is heteroaryl.
19. The compound of claim 18, wherein heteroaryl is substituted or unsubstituted indole.
20. The compound of claim 2, wherein R is selected from the group consisting of acetate, amino, and dialkylamino.
21. The compound of claim 2, wherein n is 1, 2, or 3.
22. The compound of claim 1, wherein X1 is NR11.
23. The compound of claim 22, wherein X2 is O.
24. The compound of claim 22, wherein X2 is S.
25. The compound of claim 1, wherein X1 is S.
26. The compound of claim 25, wherein X2 is O.
27. A compound of formula (III):
or a salt and or N-oxide thereof;
wherein R is selected from the group consisting of acetate, amino, dialkylamino, \u2014C(O)OH, straight or branched, saturated or unsaturated alkyl, allyl, cycloalkyl, cycloheteroalkyl, aryl, and heteroaryl, each of which is optionally substituted;
X1 is O or NR11;
R11 is H or lower alkyl; and
n is and integer between 0 and 10.
28. The compound of claim 27, wherein R is morpholine.
29. The compound of claim 27, wherein R is 1-methylpiperidine.
30. The compound of claim 27 , wherein R is piperazine or 3- piperazinepropane sulfonate.
31. The compound of claim 27, wherein R is dimethylamine.
32. The compound of claim 27, wherein R is tryptamine or N-tert-butylaceyltryptamine.
33. The compound of claim 27, wherein n is 0, 1, 2, or 3.
34. A method for of treating breast cancer, the method comprising:
administering to a subject an effective amount of a compound of claim 1 or a acceptable salt or N-oxide thereof and pharmaceutically-acceptable carrier or diluent.
35. The method of claim 34, wherein the subject is a domestic animal.
36. The method of claim 34 , wherein the subject is a human.